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Phenotype: Wasting disease is an inherited disorder of metabolism in drakes.
Drakes homozygous for the recessive wasting disease allele (wd/wd) typically exhibit symptoms prior to maturity.
Symptoms include lethargy, sleepiness, skeletal muscle weakness, and enlarged heart. Premature death from cardiac failure is common.
Biochemically, there is a 10- to 30-fold excess of carnitine in excreted waste. Plasma carnitine levels are reduced.
Symptoms improve if affected drakes are treated daily with oral L-carnitine.
Phenotype Terms:
cardiovascular system phenotype
metabolism phenotype
mortality
skeletal muscle phenotype
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