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Heritable Phenotype: gasping sickness

NomenclatureGenomic Location
SymbolgaspChromosome1
Namegasping sicknessLinkage map11 cM
SpeciesDracomimus familiarisGenome Coordinatesunknown

Summary Information
Phenotype: Gasping sickness is an inherited disorder of metabolism in drakes. Drakes homozygous for the recessive allele (gasp/gasp) typically exhibit symptoms prior to maturity. The disease gets its name from the phenotype of episodes of respiratory distress. Other symptoms include lethargy, failure to thrive, and dehydration. Symptoms are made worse by high protein intake.

Biochemically, the symptoms include methylmalonic aciduria, long chain ketonuria, and intermittent hyperglycinemia. Limited protein intake and treatment with vitamin B12 reverses the biochemical disorder and all symptoms.

Phenotype Terms:
metabolism phenotype
mortality
respiratory system phenotype

Alleles and Phenotypes
AlleleSummary
GaspPresumptive wild-type allele
gaspRecessive allele
GenotypePhenotype
Gasp/GaspNormal
Gasp/gaspNormal
gasp/gaspGasping sickness