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Heritable Phenotype: shaking sickness

NomenclatureGenomic Location
SymbolsksChromosome1
Nameshaking sicknessLinkage map77 cM
SpeciesDracomimus familiarisGenome Coordinatesunknown

Summary Information
Phenotype: Shaking sickness is an inherited disorder of metabolism in drakes. Drakes homozygous for the recessive allele (sks/sks) typically exhibit symptoms prior to maturity. The disease gets its name from the common symptom of seizures. Other symptoms include poor appetite, failure to thrive, and hypotonia.

Biochemically, the symptoms include elevated amounts of malonic, methylmalonic, and succinic acids in excreted waste. Symptoms are relieved by a low-fat, high-carbohydrate diet.

Phenotype Terms:
mortality
metabolism phenotype
behavior/neurological phenotype

Alleles and Phenotypes
AlleleSummary
SksPresumptive wild-type allele
sksRecessive allele
GenotypePhenotype
Sks/SksNormal
Sks/sksNormal
sks/sksShaking sickness