Nomenclature | Genomic Location |
Symbol | Klc2 | Chromosome | X |
Name | Kinesin light chain 2 | Linkage map | unknown |
Species | Dracomimus familiaris | Genome Coordinates | ChrX: 37 Mbp |
Molecular Function |
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Molecular Function Terms:
binding
protein binding
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Human Disease Association |
No disease association.
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1 ATGACGACCATGCTGTACCCACGCGAGGAGAAGATGAGCCAGGACGAGATAGTGCTAGGC
61 ACCAAGGCCGTGGTGCAGGGCTTGGAAACGTTACGCACGGAGCACCACTCGCTGCTGGCT
121 GCGCTGCTTGACACCGTCAACCGCATGGAGCAACAGCATGAAAGCAGCGCTGCCCAGGAG
181 AAGGCCAGTCTCTTGCGGAAGTCTCTGGAAGCCATCGAACTGGGGCTCGGGGAGGCTCAG
241 GTGATCATTGCCCTGTCCAGCCACCTGGGCGCAGTGGAATCGGAGAAACAGAAGCTGCGA
301 GCGCAAGTGCGGCGCCTGGTGCAGGAGAACCAGTGGCTGCGGGATGAACTGGCCAATACC
361 CAGCAGAAGCTGCAGTGCAGCGAGCAGGCCGTGGCCCAACTCGAGGAGGAGAAAAAACAC
421 CTGGAATTTATGAACCAGATCAAAAAATTCGACGACGACGTTTCCCCATCTGATGAGAAG
481 AGTGGGGATACATCCAAGGACACCTTAGATGACCTTTTCCCCAGTGATGATGACCAGGGA
541 CAAGGGCAGGCGCACAGCAGTGGGGACGCGGCGGCCCAGCATGGCGGCTACGAGATCCCG
601 GCCCGCCTGCGGACGCTTCACAACCTGGTGATCCAGTACGCCTCACAAGGGCGCTATGAG
661 GTGGCCGTGCCGCTCTGTAAGCAAGCGCTGGAGGATTTGGAGAAAACCTCAGGCCATGAC
721 CACCCGGATGTGGCGACCATGCTGAATATTCTTGCGCTGGTGTACAGGGACCAAAATAAA
781 TACAAGGAGGCAGCCCACCTTCTCAACGATGCCTTGGCCATCCGGGAGAAAACACTGGGG
841 AAAGATCACCCAGCTGTGGCTGCTACTCTCAACAACCTGGCCGTTTTGTATGGCAAAAGG
901 GGCAAATACAAGGAAGCAGAGCCCCTGTGCAAGAGAGCTCTGGAGATCCGGGAAAAGGTA
961 CTCGGGAAGTACCACCCGGACGTAGCCAAGCAGTTGAACAACTTGGCCCTCCTGTGCCAG
1021 AACCAAGGCAAGTATGAGGAGGTCCAGTACTATTACCGGCGCGCCCTCGAGATCTACGAG
1081 TCACGCCTCGGGCCCGACGATCCCAACGTGGCCAAGACCAAAAACAACCTGGCATCCTGC
1141 TACCTCAAGCAAGGCAAATACAAGGATGCAGAGGCGCTCTACAAGGAAATCCTGACCCGG
1201 GCGCATGAGAGAGAATTTGGGTCTGTCAATGGAGACAACAAGCCCATCTGGATGCATGCC
1261 GAGGAGCGGGAGGAGAGCAAGGATAAGCGCAGGGAGAAGGACAGCGCTCCTTACGGGGAG
1321 TATGGCAGCTGGTACAAAGCCTGCAAAGTGGACAGCCCTACGGTCAACACAACGCTAAAA
1381 AGCCTGGGGGCTCTCTATCGGCGCCAAGGCAAGCTAGAGGCTGCAGAGACACTGGAAGAA
1441 TGTGCCCAGAAAACCCGCAAACAGGGCATGGATGCCATCAACCAGAGCAAAGTAGTGGAA
1501 CTCCTGAAGGATGGCAACCGTTCGGAGCACTGGCAGAACCGAGAGGGCGTTTCCAGCACC
1561 AACAAATGCGAAAATGGGAACGAAGCTGAGGACGGAACGGCCGAATGGTCTGGGATGGGC
1621 TCTGGGGCCCTGCAGCGCAGCAGCTCCTTTGGGAAACTACGCGATGCTCTGCGGCGGAGC
1681 AGTGAGATGCTGGTGAAAAAGCTGCAAGGGAGCAGCCCTCAGGAACCCAGGAATTTGGGG
1741 ATGAAGCGGGCCAGCTCTCTCAACTTTTTGAACAAGAGCGTAGAAGAGGAGTCAAGCCAG
1801 GTTTCCAGCAGCCTGTCCGACAGCCGGGGCCTTAGCGCGAGTAATGTCGACCTCTCCCGG
1861 CGCAGTTCTCTGCTGGCATGA
Predicted Protein Product |
MTTMLYPREEKMSQDEIVLGTKAVVQGLETLRTEHHSLLAALLDTVNRMEQQHESSAAQE
KASLLRKSLEAIELGLGEAQVIIALSSHLGAVESEKQKLRAQVRRLVQENQWLRDELANT
QQKLQCSEQAVAQLEEEKKHLEFMNQIKKFDDDVSPSDEKSGDTSKDTLDDLFPSDDDQG
QGQAHSSGDAAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD
HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR
GKYKEAEPLCKRALEIREKVLGKYHPDVAKQLNNLALLCQNQGKYEEVQYYYRRALEIYE
SRLGPDDPNVAKTKNNLASCYLKQGKYKDAEALYKEILTRAHEREFGSVNGDNKPIWMHA
EEREESKDKRREKDSAPYGEYGSWYKACKVDSPTVNTTLKSLGALYRRQGKLEAAETLEE
CAQKTRKQGMDAINQSKVVELLKDGNRSEHWQNREGVSSTNKCENGNEAEDGTAEWSGMG
SGALQRSSSFGKLRDALRRSSEMLVKKLQGSSPQEPRNLGMKRASSLNFLNKSVEEESSQ
VSSSLSDSRGLSASNVDLSRRSSLLA
Protein Alignment to Mouse |
sp|O88448|KLC2_MOUSE Kinesin light chain 2 OS=Mus musculus GN=Klc2 PE=1 SV=1
Length = 599
Score = 2074 (735.1 bits), Expect = 2.4e-215, P = 2.4e-215
Identities = 425/592 (71%), Positives = 464/592 (78%)
Query: 1 MTTMLYPREEKMSQDEIVLGTKAVVQGLETLRTEHHSLLAALLDTVNRMEQQHESSAAQE 60
M TM+ PREEK+SQDEIVLGTKAV+QGLETLR EH +LLA L E +QE
Sbjct: 1 MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASH----EAGEAEPGSQE 56
Query: 61 KASLLRKSLEAIELGLGEAQVIIALSSHLGAVESEKQKLRAQVRRLVQENQWLRDELANT 120
+ LLR+SLEAIELGLGEAQVI+ALSSHLGAVESEKQKLRAQVRRLVQENQWLR+ELA T
Sbjct: 57 RCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGT 116
Query: 121 QQKLQCSEQAVAQLEEEKKHLEFMNQIKKFDDDVSPSDEKSGDTSKXXXXXXXXXXXXQG 180
QQKLQ SEQAVAQLEEEK+HL FM+QI+K D+ + P +EK GD K Q
Sbjct: 117 QQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDE-MLPQEEK-GDVPKDSLDDLFPNEDEQS 174
Query: 181 QGQAHSSGDAAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD 240
+ GD AAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD
Sbjct: 175 PAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD 234
Query: 241 HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPXXXXXXXXXXXXYGKR 300
HPDVATMLNILALVYRDQNKYK+AAHLLNDALAIREKTLGKDHP YGKR
Sbjct: 235 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 294
Query: 301 GKYKEAEPLCKRALEIREKVLGKYHPDVAKXXXXXXXXXXXXGKYEEVQYYYRRALEIYE 360
GKYKEAEPLCKRALEIREKVLGK+HPDVAK GK EEV+YYYRRALEIY
Sbjct: 295 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 354
Query: 361 SRLGPDDPNVAKTKNNLASCYLKQGKYKDAEALYKEILTRAHEREFGSVNGDNKPIWMHA 420
+RLGPDDPNVAKTKNNLASCYLKQGKY+DAE LYKEILTRAHE+EFGSVNG+NKPIWMHA
Sbjct: 355 TRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHA 414
Query: 421 XXXXXXXXXXXXXXXAPYGEYGSWYKACKVDSPTVNTTLKSLGALYRRQGKLEAAETLEE 480
P EYGSWYKACKVDSPTVNTTL++LGALYR +GKLEAA TLE+
Sbjct: 415 EEREESKDKRRDRR--PM-EYGSWYKACKVDSPTVNTTLRTLGALYRPEGKLEAAHTLED 471
Query: 481 CAQKTRKQGMDAINQSKVVELLKDGNRSEHWQNREGVSSTNKCENGNEAEDGTAEWSGMG 540
CA ++RKQG+D +Q+KVVELLKDG+ H + V+ E+ E AEWSG G
Sbjct: 472 CASRSRKQGLDPASQTKVVELLKDGSGRGHRRGSRDVAGPQS-ESDLEESGPAAEWSGDG 530
Query: 541 SGALQRSSSFGKLRDALRRSSEMLVKKLQGSSPQEPRNLGMKRASSLNFLNK 592
SG+L+RS SFGKLRDALRRSSEMLV+KLQG PQEP N MKRASSLNFLNK
Sbjct: 531 SGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEP-NSRMKRASSLNFLNK 581
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