| Nomenclature | Genomic Location |
| Symbol | Trak2 | Chromosome | X |
| Name | Trafficking protein,
kinesin binding 2 | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | ChrX: 38 Mbp |
| Molecular Function |
|
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Molecular Function Terms:
binding
protein binding
enzyme binding
receptor binding
|
| Human Disease Association |
|
No disease association.
|
1 TTCTGGTTTTCAGTTCTTAGCACAGAGAGACGAGATCAAGTGACAAATAACTGCAATGAT
61 AGCGAAGTGGTCACACATCTACTGGCAGAGAGAGATCGGGACCTAGAATTAGCAGCACGA
121 ATTGGCCAAGCCCTATTGAAACGGAACCATATACTTACTGAGCAAAATGAAGCTTTGGAA
181 GAACAATTGGCTCAAGCCTTTGACAAGGTTCACCAACTACAGCACGAGCTGACAAAAAAA
241 GATGAACTGCTTCGTGTAGTTTCTATTGCTTCTGAAGAAAGTGAGACTGACTCAAGCTGT
301 TCCACACCTCTTCGCTTCAATGAGTCCTTCAACCTGTCACAGGGCCTTGTACAGCTGGAT
361 ATATTACAGGATAAACTCAGGGACCTGGAGGAGGAAAACCTTTCTCTTCGAACGAAGGCC
421 TGCCATTTGAAGACGGAAACCATGACTTATGAAGAAAAAGAGCAGCAGCTGGTCAGTGAC
481 TGTGTCAAAGAGATCAGGGAAACACATGCCCAAATTGCACAAATGAGTGAGGAGTTGACC
541 AGAAAAAATGACGAGCTGCTTAACTACCAGGAGGAGATTTCATCCCTCTTGTCACAGATC
601 GTTGATCTTCAGCATAAAATCAAAGAGCATGTAATTGAAAAGGAAGAATTGAAATTGCAC
661 CTGCAAGCTTCCAAAGATGCACAGAGACAGCTGACAGCAGAGCTACATGACTTACAAGAG
721 CGGAATGCAGAATGCCTGGGGATGTTGCATGAGTCACAAGAAGAAGCCAAGGGACTACGC
781 AGCAAAGCCAGCCAAGCTGCCCTTCTCTGCCGCCCCCAGTCATATGGAGCATTTCCTGTG
841 GACTCTTTGGCAGCAGAGATCGAGGGGACGATGAGGAAAGAACTGAGTTTGGAGGAAGAA
901 TCTGTCTCTAAGCAAAAGGTGCAGCAGAAGCGTGTGTTTGACACTGTCCGTGTTGCTAAT
961 GTGATACGTGGCCGCTCTGCTTTGTGTCCTGCTCCACTGCCCATCCCAGGGTCAAATCGC
1021 TCAAGTGTAGTCATGACCGCAAAGCCTTTTCTTTCTGGAATGCCACACCTGGAAGGAAAG
1081 GTGCATCAATCTCAGGGGATCAGGTCAGAAAGCATTTTCAAGGAACCTCAGAAGTTGGGC
1141 CATGATGCCATTCCCAAGGAGGGTGATTTAGCTACAGCTCTGCACAGGCTCACTCTCCGC
1201 CGTCAGAACTACCTGAGTGAAAAGCAATTTTTTGAAGAAGAGTGGGAGCGCAGGATCAAT
1261 TTCCTGGCTGACCAGAAGGAAGATCCGAGTGGCTGTAGCACTCCAGTGGAGAGCTGCTTT
1321 TCTCTGGGAAGCTATTCAGAGCTTTCTGATTTCTCTGGGACCTCCAGCAGCTTACGTTGT
1381 CTCCTTCCAGAGAAATTGCAAATTGTCAAACCTATTGAAGGCTCCCAGACACTCTTCCAC
1441 TGGCAGCAGTTGGCTCAGCCTCACCTCGGTACCATTCTTGACCCGCGCCCTGGTGTTGTC
1501 ACAAAAGGTTTTGCACCACTTTCACAAGATGATGTCTACCATCTTTCTGATTTGGAAGAA
1561 GATGGAGAGAAGGATGAAGGCATAACCTTCCAAGTGCAACAGTCTCCTCAAGAGGAAGGG
1621 AAGCCCAGAGTGCCAAAGTCGGTGGCTGGAATTTTCTTACCACCTGCTAAACTAGCAACA
1681 GTTCCCCTCACAGTTGCAGCTTCCAACCCAGGAAAATGCCTCTCATCTACAAACTCTACT
1741 TTTACTTATACTAATTGTAGAATCCTCCACCCATCTGATATCACACAGGTTACGCCCAGC
1801 TCTTCATATGCTCCCTTGTGCTCTGGGAGCCCTAGCAGCACCACCAGTACAGTGGCAAGC
1861 TCCCCCGCCACATCATGCAGGTTCAGCATTGGAGAATTCCTCACTAACAGGAGGGACTCC
1921 ACTACCACCTTCAGCAGCACTACAAGCTTGGCTAAACTCTTGCAAGAGCAGGGCATCTCT
1981 GCAAAGGTCTACAATAGTCCAGCTTTGGAGAATGCACCTTTGTTACAGCCACTCAAGATA
2041 CTCGCTGTTCCCTCAACGCCACCCAATTCCCCTTTGCATTCGCCTTGTCCTTCCCCTTTG
2101 CCTTTTGACTCTCGAGCAAATGCACTTGAGAATTTTTTGGCCTCTCGGCCTGCCGAAACC
2161 TTACTGCCGGAGATGTATGGCCCGAAGGCTTCTAATTGTGATGCAGGACAACTGAAGATG
2221 AACCTGGTGGAAAGGCTGAAGAAATTGGGGATTGCCAGAGTTGTCAAACATCCTGAGGCA
2281 GGGGATGGTGGGAAGGGTCATGGGGCAAGGAATGCCCTCCAGAGGCAGGACTCTGCTGTA
2341 TACGTCAATGCAGGCAGCAATCTGATGGGAGGCCTGAGAAGAAACCACAGCCTCCCAGTC
2401 ATGATCGGGGCCCTTGGAGGCCCCCTGAGCACATCGTCCTCAAAGATGGGAGTCCTCAAG
2461 GAGAATTGA
| Predicted Protein Product |
FWFSVLSTERRDQVTNNCNDSEVVTHLLAERDRDLELAARIGQALLKRNHILTEQNEALE
EQLAQAFDKVHQLQHELTKKDELLRVVSIASEESETDSSCSTPLRFNESFNLSQGLVQLD
ILQDKLRDLEEENLSLRTKACHLKTETMTYEEKEQQLVSDCVKEIRETHAQIAQMSEELT
RKNDELLNYQEEISSLLSQIVDLQHKIKEHVIEKEELKLHLQASKDAQRQLTAELHDLQE
RNAECLGMLHESQEEAKGLRSKASQAALLCRPQSYGAFPVDSLAAEIEGTMRKELSLEEE
SVSKQKVQQKRVFDTVRVANVIRGRSALCPAPLPIPGSNRSSVVMTAKPFLSGMPHLEGK
VHQSQGIRSESIFKEPQKLGHDAIPKEGDLATALHRLTLRRQNYLSEKQFFEEEWERRIN
FLADQKEDPSGCSTPVESCFSLGSYSELSDFSGTSSSLRCLLPEKLQIVKPIEGSQTLFH
WQQLAQPHLGTILDPRPGVVTKGFAPLSQDDVYHLSDLEEDGEKDEGITFQVQQSPQEEG
KPRVPKSVAGIFLPPAKLATVPLTVAASNPGKCLSSTNSTFTYTNCRILHPSDITQVTPS
SSYAPLCSGSPSSTTSTVASSPATSCRFSIGEFLTNRRDSTTTFSSTTSLAKLLQEQGIS
AKVYNSPALENAPLLQPLKILAVPSTPPNSPLHSPCPSPLPFDSRANALENFLASRPAET
LLPEMYGPKASNCDAGQLKMNLVERLKKLGIARVVKHPEAGDGGKGHGARNALQRQDSAV
YVNAGSNLMGGLRRNHSLPVMIGALGGPLSTSSSKMGVLKEN
| Protein Alignment to Mouse |
tr|Q6P9N8|Q6P9N8_MOUSE Trafficking protein, kinesin binding 2 OS=Mus musculus
GN=Trak2 PE=2 SV=1
MGI:2139395 Golga2 golgi autoantigen, golgin subfamily a, 2 (Chr 2)
Length = 913
Score = 2335 (827.0 bits), Expect = 5.4e-243, P = 5.4e-243
Identities = 492/827 (59%), Positives = 575/827 (69%)
Query: 1 FWFSVLSTERRDQVTNNCNDSEVVTHLLAERDRDLELAARIGQALLKRNHIXXXXXXXXX 60
F + +L T+R +Q+T ND ++VTHLLAERDRDLELAARIGQALLKRNH+
Sbjct: 92 FRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNEALE 151
Query: 61 XXXXXXFDKVHQLQHELTKKDELLRVVSIAXXXXXXXXXXXXPLRFNESFNLSQGLVQLD 120
FD+V+QLQHEL+KKDELLR+VSIA PLRFNESF+LSQGL+QLD
Sbjct: 152 EQLGQAFDQVNQLQHELSKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLD 211
Query: 121 ILQDKLRDLEEENLSLRTKACHLKTETMTYEEKEQQLVSDCVKEIRETHAQIAQMSEELT 180
+L +KLR+LEEEN++LR+KACH+KTET TYEEKEQQLV+DCVKE+RET+AQ+++M+EEL+
Sbjct: 212 MLHEKLRELEEENMALRSKACHIKTETFTYEEKEQQLVNDCVKELRETNAQMSRMTEELS 271
Query: 181 RKNDELLNYQEEISSLLSQIVDLQXXXXXXXXXXXXXXXXXQASKDAQRQLTAELHDLQE 240
K+DELL YQEEISSLLSQIVDLQ QASKDAQRQLT ELH+LQ+
Sbjct: 272 GKSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQD 331
Query: 241 RNAECLGMLHESQEEAKGLRSKASQAALLCRPQSYGAFPVDSLAAEIEGTMRKXXXXXXX 300
RN ECLGMLHESQEE K LRSK+ +A LC QSYG F +SLAAEIEGTMRK
Sbjct: 332 RNMECLGMLHESQEEIKELRSKSGPSAHLCFSQSYGVFTGESLAAEIEGTMRKKLSLDEE 391
Query: 301 XVSKQKVQQKRVFDTVRVANVIRGRSALCPAPLPIPGSNRSSVVMTAKPFLSGMPHLEGK 360
VSKQK QQKRVFDTV+VAN RGRS P LPIPGSNRSSV+MTAKPF SG+ E K
Sbjct: 392 SVSKQKAQQKRVFDTVKVANDTRGRSVTFPVLLPIPGSNRSSVIMTAKPFESGVQPAEDK 451
Query: 361 VHQSQGIRSESIFKEPQKLGHDAIPKEGDXXXXXXXXXXXXQNYLSEKQFFEEEWERRIN 420
S G +E + Q P++ D QNYLSEKQFF EEWER+I
Sbjct: 452 TLLSPGGSTE-VPGNSQPTNPPGSPEDSDLATALHRLSLRRQNYLSEKQFFAEEWERKIQ 510
Query: 421 FLADQKEDPSGCSTPVESCFSLGS-YSELSDFSGTSSSLRCLLPEKLQIVKPIEGSQTLF 479
LA+Q+E+ S C P E+ S+ + SE +D G++S LR +PEKLQIVKP+EGSQTL
Sbjct: 511 ILAEQEEEVSSCDAPTENLASVCTDQSETTDL-GSASCLRGFMPEKLQIVKPLEGSQTLH 569
Query: 480 HWQQLAQPHLGTILDPRPGVVTKGFAPLSQDDVYHLSDLEEDGEKDEGITFQVQQSPQEE 539
HWQQLAQP+LGTILDPRPGV+TKGF + +D VYH+SDLEED E EGITFQVQQ Q E
Sbjct: 570 HWQQLAQPNLGTILDPRPGVITKGFTQVPKDVVYHISDLEEDEE--EGITFQVQQPLQLE 627
Query: 540 GKPRVPKSVAGIFLPPAKLATVPLTVAASNPGKCLSSTNSTFTYTNCRILHPSDITQVTP 599
KP +P V GIFLPP A P TVA SNPGKCLS TNSTFT+T CRILHPSDITQVTP
Sbjct: 628 QKPALPTPVTGIFLPPMTSAGGPGTVATSNPGKCLSFTNSTFTFTTCRILHPSDITQVTP 687
Query: 600 SSSYAPL-CXXXXXXXXXXXXXXXXXXCRFSIGEFLTNRRDXXXXXXXXXXLAKLLQEQG 658
SS + L C R SIGE +TNRRD LAKLLQE+G
Sbjct: 688 SSGFPSLACGSSASSSSNTAVNSPAASYRLSIGESITNRRDSTITFSSTRSLAKLLQERG 747
Query: 659 ISAKVYNSPALENAPLLQPL-KILAVPSTXXXXXXXXXXXXXXXFDSRANALENFLASRP 717
ISAKVY+SPA EN PLLQP K LA PST F+ R + ENFLASRP
Sbjct: 748 ISAKVYHSPASEN-PLLQPCPKALATPSTPPNSPAQSPCSSPLPFEPRVHVSENFLASRP 806
Query: 718 AETLLPEMYGPKASNC--DAGQLKMNLVERLKKLGIARVVKHPEAGDGGKGHGARNALQR 775
AET L EMYG + S D GQLKMNLV+RLK+LGIARVVK P+ + GK A LQ+
Sbjct: 807 AETFLQEMYGLRPSRAPPDVGQLKMNLVDRLKRLGIARVVKTPDPQENGKSREAEMGLQK 866
Query: 776 QDSAVYVNAGSNLMGGLRRNHSLPVMIGALGGPLSTSSSKMGVLKEN 822
D AVY+N+G +L+ GLRRN SLPVM+G+ G P+ T+S KMG+LKE+
Sbjct: 867 PDPAVYLNSGGSLLCGLRRNQSLPVMMGSFGAPVCTTSPKMGILKED 913
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