| Nomenclature | Genomic Location |
| Symbol | Got1 | Chromosome | X |
| Name | Glutamate oxaloacetate
transaminase 1 | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | ChrX: 65 Mbp |
| Molecular Function |
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Plays a key role in amino acid metabolism.
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
Molecular Function Terms:
binding
carboxylic acid binding
catalytic activity
lyase activity
carbon-carbon lyase activity
carboxy-lyase activity
transferase activity
transferase activity, transferring nitrogenous groups
transaminase activity
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| Human Disease Association |
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No disease association.
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1 TCCGTCTTTGCCGCCGTCCCGCAAGCCCTGCCGGTGGCCGTCTTCCAGCTCACGGCGGAT
61 TTCCGCGCCGACGCCGATCCTCGCAAGGTCAACCTGGGCGTGGGAGCCTATCGTACGGAC
121 GAGGGGCAGCCATGGGTCTTACCAGTGGTTCGCAAGGTAGAAACAATGATTACCAAGGAC
181 ACCAGCTTGAACCATGAATACCTTCCCATCTTGGGCTTGCCAGAATTTCGTGCCAATTCC
241 TCTCGAATTGCTCTTGGGGATGATAGTCCAGCCATCAAGGAGAATAGGGTTGGAGGTGTA
301 CAGTCCTTGGGGGGCACAGGGGCTCTCCGTATTGGAGCAGAGTTCCTGAGACGCTGGTAC
361 AATGGAACCAACAACACAGCAACACCTGTATACATCTCTTCCCCTACCTGGGAAAATCAT
421 AATTCTGTCTTCACGGATGCTGGCTTCAAAGACATCCGCAGCTATCGCTATTGGGATGCT
481 GCAAAAAGGGGTCTGGACATACAAGGATTTCTGGAGGACTTGGAGAAAGCTCCAGAATTT
541 TCCATCTTCATCCTTCATGCTTGTGCTCATAATCCAACTGGCACAGATCCCACTCAGGAG
601 CAATGGAAACAAATAGCAGCTGTCATGAAGCGCCGGTTCCTGTTCCCATTTTTTGACTCT
661 GCCTACCAAGGCTTTGCCTCAGGTTCCCTGGACAGAGATGCATGGGCTGTCCGCTACTTT
721 GTTTCAGAAGGCTTTGAACTCTTCTGTGCACAGTCCTTCTCAAAAAATTTTGGCCTGTAC
781 AATGAGCGTGTGGGAAACCTGACTGTCGTGGCAAAGGATGGAGAAAACGTGCAGCGGGTT
841 TTATCCCAGATGGAAAAGATTGTCCGCACCACTTGGTCTAACCCCCCTTCCCAGGGGGCA
901 CGGATTGTGGCCACGACACTCACTACCCCAGAGCTTTTTGCTGAATGGAAAGGGAATGTG
961 AAGACCATGGCAGACCGTGTCTTGCTGATGCGGGCAGAGCTCAGATCTCGGCTTGAGGCC
1021 CTTCACACACCAGGCACTTGGAATCACATAACGGAGCAGATTGGCATGTTTAGCTTTACC
1081 GGCCTCAATCCTAAGCAAGTCCTTTTCCTGATCAAAGAAAAACACATCTACCTGATGGCT
1141 AGTGGCCGCATCAACATGTGTGGTTTGACAGCAAAGAATCTGGACTACGTCGCCGCTTCC
1201 ATCCATGAAGCTGTCACTAAGATCCAG
| Predicted Protein Product |
SVFAAVPQALPVAVFQLTADFRADADPRKVNLGVGAYRTDEGQPWVLPVVRKVETMITKD
TSLNHEYLPILGLPEFRANSSRIALGDDSPAIKENRVGGVQSLGGTGALRIGAEFLRRWY
NGTNNTATPVYISSPTWENHNSVFTDAGFKDIRSYRYWDAAKRGLDIQGFLEDLEKAPEF
SIFILHACAHNPTGTDPTQEQWKQIAAVMKRRFLFPFFDSAYQGFASGSLDRDAWAVRYF
VSEGFELFCAQSFSKNFGLYNERVGNLTVVAKDGENVQRVLSQMEKIVRTTWSNPPSQGA
RIVATTLTTPELFAEWKGNVKTMADRVLLMRAELRSRLEALHTPGTWNHITEQIGMFSFT
GLNPKQVLFLIKEKHIYLMASGRINMCGLTAKNLDYVAASIHEAVTKIQ
| Protein Alignment to Mouse |
sp|P05201|AATC_MOUSE Aspartate aminotransferase, cytoplasmic OS=Mus musculus
GN=Got1 PE=1 SV=2
Length = 413
Score = 1825 (647.5 bits), Expect = 5.9e-189, P = 5.9e-189
Identities = 340/409 (83%), Positives = 370/409 (90%)
Query: 1 SVFAAVPQALPVAVFQLTADFRADADPRKVNLGVGAYRTDEGQPWVLPVVRKVETMITKD 60
SVFA VPQA PV VF+LTADFR D DPRKVNLGVGAYRTDE QPWVLPVVRKVE I D
Sbjct: 5 SVFAQVPQAPPVLVFKLTADFRDDPDPRKVNLGVGAYRTDESQPWVLPVVRKVEQKIAND 64
Query: 61 TSLNHEYLPILGLPEFRANSSRIALGDDSPAIKENRVGGVQSLGGTGALRIGAEFLRRWY 120
SLNHEYLPILGL EFR+ +SR+ LGD+SPAI+ENRVGGVQSLGGTGALRIGA+FL RWY
Sbjct: 65 NSLNHEYLPILGLAEFRSCASRLVLGDNSPAIRENRVGGVQSLGGTGALRIGADFLGRWY 124
Query: 121 NGTNNTATPVYISSPTWENHNSVFTDAGFKDIRSYRYWDAAKRGLDIQGFLEDLEKAPEF 180
NGT+N TP+Y+SSPTWENHN+VF+ AGFKDIR Y YWDA KRGLD+QGFL DLE APEF
Sbjct: 125 NGTDNKNTPIYVSSPTWENHNAVFSAAGFKDIRPYCYWDAEKRGLDLQGFLNDLENAPEF 184
Query: 181 SIFILHACAHNPTGTDPTQEQWKQIAAVMKRRFLFPFFDSAYQGFASGSLDRDAWAVRYF 240
SIF+LHACAHNPTGTDPT EQWKQIAAVM+RRFLFPFFDSAYQGFASG L++DAWA+RYF
Sbjct: 185 SIFVLHACAHNPTGTDPTPEQWKQIAAVMQRRFLFPFFDSAYQGFASGDLEKDAWAIRYF 244
Query: 241 VSEGFELFCAQSFSKNFGLYNERVGNLTVVAKDGENVQRVLSQMEKIVRTTWSNPPSQGA 300
VSEGFELFCAQSFSKNFGLYNERVGNLTVV K+ ++V RVLSQMEKIVR TWSNPP+QGA
Sbjct: 245 VSEGFELFCAQSFSKNFGLYNERVGNLTVVGKESDSVLRVLSQMEKIVRITWSNPPAQGA 304
Query: 301 RIVATTLTTPELFAEWKGNVKTMADRVLLMRAELRSRLEALHTPGTWNHITEQIGMFSFT 360
RIVA TL+ PELF EWKGNVKTMADR+L MR+ELR+RLEAL TPGTW+HITEQIGMFSFT
Sbjct: 305 RIVAATLSDPELFKEWKGNVKTMADRILTMRSELRARLEALKTPGTWSHITEQIGMFSFT 364
Query: 361 GLNPKQVLFLIKEKHIYLMASGRINMCGLTAKNLDYVAASIHEAVTKIQ 409
GLNPKQV +L+ EKHIYL+ SGRINMCGLT KNLDYVA SIHEAVTKIQ
Sbjct: 365 GLNPKQVEYLVNEKHIYLLPSGRINMCGLTTKNLDYVATSIHEAVTKIQ 413
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