| Nomenclature | Genomic Location |
| Symbol | Gnb4 | Chromosome | 2 |
| Name | Guanine nucleotide-binding
protein subunit beta-4 | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | Chr2: 7 Mbp |
| Molecular Function |
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Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in
various transmembrane signaling systems. The beta and gamma chains are required for the GTPase
activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Molecular Function Terms:
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
nucleoside-triphosphatase activity
GTPase activity
molecular transducer activity
signal transducer activity
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| Human Disease Association |
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No disease association.
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1 ATGAGTGAACTGGAACAGTTACGGCAGGAGGCTGAACAACTCCGGAATCAAATCAGAGAT
61 GCCAGAAAAGCATGTAGTGACACAACTCTTGCTCAGATCACCACAAGTCTTGACTCAGTG
121 GGTCGAATCCAGATGCGCACAAGACGTACGCTGAGAGGCCATTTAGCTAAAATTTATGCC
181 ATGCATTGGGGAACTGATTCAAGGCTACTAGTGAGTGCTTCCCAAGATGGAAAATTAATT
241 ATTTGGGATAGTTATACAACAAACAAGATGCATGCCATTCCTTTGAGGTCTTCCTGGGTA
301 ATGACCTGTGCATATGCGCCATCTGGCAATTACGTCGCCTGTGGTGGATTGGACAACATC
361 TGCTCCATCTACAACCTGAAGACAAGAGAGGGCAACGTGCGAGTGAGCAGGGAGCTACCC
421 GGCCATACTGGGTATCTGTCCTGTTGCCGATTTCTAGATGACAACCAAATAGTCACAAGC
481 TCAGGAGATACCACTTGTGCGTTGTGGGATATCGAGACCGGGCAACAGACTACTACTTTC
541 ACTGGGCATACTGGAGATGTAATGAGTCTTTCTCTAAGTCCAGACATGAGTACTTTTGTT
601 TCAGGAGCATGTGATGCATCATCCAAGCTCTGGGATATTCGAGACGGGATGTGCAGGCAG
661 TCTTTCACAGGGCATGTCTCTGACATAAACGCAGTGTGTTTCTTCCCTAATGGCCATGCC
721 TTTGCCACTGGCTCTGATGATGCCACCTGCCGACTCTTTGATCTGCGAGCCGACCAGGAG
781 CTAATGATGTACTCTCATGACAACATCATCTGCGGAATTACTTCGGTCGCTTTCTCAAAG
841 AGTGGCCGCCTTTTGTTGGCAGGTTATGATGACTTCAATTGCAATGTTTGGGACACCCTC
901 AAGGGAGAACGCGCAGGTGTCCTTGCTGGCCATGACAACCGAGTCAGCTGCTTAGGAGTT
961 ACTGATGATGGCATGGCAGTAGCTACAGGGTCTTGGGACAGTTTTCTCAGAATCTGGAAT
1021 TAA
| Predicted Protein Product |
MSELEQLRQEAEQLRNQIRDARKACSDTTLAQITTSLDSVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
TGHTGDVMSLSLSPDMSTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVCFFPNGHA
FATGSDDATCRLFDLRADQELMMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL
KGERAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
| Protein Alignment to Mouse |
sp|P29387|GBB4_MOUSE Guanine nucleotide-binding protein subunit beta-4 OS=Mus
musculus GN=Gnb4 PE=2 SV=4
MGI:104581 Gnb4 guanine nucleotide binding protein (G protein), beta 4 (Chr 3)
Length = 340
Score = 1563 (555.3 bits), Expect = 3.4e-161, P = 3.4e-161
Identities = 288/323 (89%), Positives = 302/323 (93%)
Query: 18 IRDARKACSDTTLAQITTSLDSVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDG 77
I+DARKAC+D TL QIT+++DSVGRIQMRTRRTLRGHLAKIYAMHWG DSRLLVSASQDG
Sbjct: 18 IQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDG 77
Query: 78 KLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSR 137
KLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSR
Sbjct: 78 KLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSR 137
Query: 138 ELPGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLSPDMS 197
ELPGHTGYLSCCRFLDD QI+TSSGDTTCALWDIE DVMSLSLSPD+
Sbjct: 138 ELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 197
Query: 198 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVCFFPNGHAFATGSDDATCRLFDLRA 257
TFVSGACDASSKLWDIRDGMCRQSFTGH+SDINAV FFP+G+AFATGSDDATCRLFDLRA
Sbjct: 198 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA 257
Query: 258 DQELMMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGERAGVLAGHDNRVSC 317
DQEL++YSHDNIICGITSVAFSKSGRLLLAGYDDFNC+VWD LKG R+GVLAGHDNRVSC
Sbjct: 258 DQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSC 317
Query: 318 LGVTDDGMAVATGSWDSFLRIWN 340
LGVTDDGMAVATGSWDSFLRIWN
Sbjct: 318 LGVTDDGMAVATGSWDSFLRIWN 340
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