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Gene Model: Gna14

NomenclatureGenomic Location
SymbolGna14Chromosome2
NameGuanine nucleotide-binding protein
subunit alpha-14		Linkage mapunknown
SpeciesDracomimus familiarisGenome CoordinatesChr2: 47 Mbp

Molecular Function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Molecular Function Terms:

binding
   nucleotide binding
      purine nucleotide binding
         guanyl nucleotide binding
            guanyl ribonucleotide binding
               GTP binding
   protein binding
      protein complex binding
         G-protein beta/gamma-subunit complex binding
      receptor binding
         G-protein-coupled receptor binding

molecular transducer activity
   signal transducer activity

Human Disease Association

No disease association.

Predicted Transcript
     1 CTTGCAGGTACAGGAGAAAGTGGAAAGAGTACATTTATTAAACAGATGAGGATTATTCAT
    61 GGAACAGGCTACACGGAAGAAGATCGGAAAGGCTTCCAAAAATTGGTTTATCAAAATATC
   121 TATTCTGCTATGCAGGCTATGATCAGAGCGATGGATGCTTTACAAATACCATATTCATCT
   181 GAGCAGTGCAAGGAGAATGGCCAGATGATTGAAAAAGTGGATGTAGACAAAGTAACAACG
   241 TTGGAAAGCAAACACGTGGAAGCAATTAAAAGGTTGTGGGAGGACCTGGGAATTCAAGAA
   301 TGCTATGATAGGCGGAGAGAATACCAGTTGTCAGACTCAGCTAAATATTACCTATCAGAC
   361 TTAGACCGTATTGCCATGCCATCATTTTTGCCAACTGAGCAAGATGTTCTCAGAGTGAGA
   421 GTACCAACCACCGGAATTATTGAATATCCTTTTGAGCTAGAAAATATTATTTTTAGAATG
   481 GTAGATGTCGGTGGACAGAGATCAGAAAGAAGGAAATGGATTCACTGTTTTGAAAGTGTT
   541 ACCTCCATAATATTCTTAGTTGCCTTGAGTGAATATGACCAAGTCTTGGCAGAATCTGAC
   601 AATGAGAATCGTTTGGAAGAAAGCAAGGCCTTATTCAAAACAATCATCACATACCCTTGG
   661 TTTTCAAATTCATCAATCATTTTATTTTTAAATAAAAAGGATCTTTTAGAAGAGAAGATT
   721 ATGTATTCCCATTTGGTCACCTATTTCCCACAGTTCACAGGTCCGAAGCAAGATGTTAAA
   781 GCTGCTAAAGACTTCATTCTGAATTTATACCAGGAGCAGAATCCAGACAAAGAGAAAGTG
   841 ATGTATTCCCATTTTACCTGTGCCACTGACACAGAGAACATTCGATTTGTCTTCGCTGCC
   901 GTGAAAGACACCATCCTGAATATAAATCTGAAGGAGTTCAACTTGGCATAA

Predicted Protein Product
LAGTGESGKSTFIKQMRIIHGTGYTEEDRKGFQKLVYQNIYSAMQAMIRAMDALQIPYSS
EQCKENGQMIEKVDVDKVTTLESKHVEAIKRLWEDLGIQECYDRRREYQLSDSAKYYLSD
LDRIAMPSFLPTEQDVLRVRVPTTGIIEYPFELENIIFRMVDVGGQRSERRKWIHCFESV
TSIIFLVALSEYDQVLAESDNENRLEESKALFKTIITYPWFSNSSIILFLNKKDLLEEKI
MYSHLVTYFPQFTGPKQDVKAAKDFILNLYQEQNPDKEKVMYSHFTCATDTENIRFVFAA
VKDTILNINLKEFNLA
Protein Alignment to Mouse
sp|P30677|GNA14_MOUSE Guanine nucleotide-binding protein subunit alpha-14
            OS=Mus musculus GN=Gna14 PE=1 SV=1
        Length = 355

 Score = 1408 (500.7 bits), Expect = 9.2e-145, P = 9.2e-145
 Identities = 266/315 (84%), Positives = 294/315 (93%)

Query:     1 LAGTGESGKSTFIKQMRIIHGTGYTEEDRKGFQKLVYQNIYSAMQAMIRAMDALQIPYSS 60
             L GTGESGKSTFIKQMRIIHG+GY++EDRKGF KLVYQNI++AMQAMIRAMD L+I Y  
Sbjct:    40 LLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMC 99

Query:    61 EQCKENGQMIEKVDVDKVTTLESKHVEAIKRLWEDLGIQECYDRRREYQLSDSAKYYLSD 120
             EQ KEN Q+I +V+VDKVT L    V AIK+LW D GIQECYDRRREYQLSDSAKYYL+D
Sbjct:   100 EQNKENAQIIREVEVDKVTALSRDQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTD 159

Query:   121 LDRIAMPSFLPTEQDVLRVRVPTTGIIEYPFELENIIFRMVDVGGQRSERRKWIHCFESV 180
             ++RIAMPSF+PT+QDVLRVRVPTTGIIEYPF+LENIIFRMVDVGGQRSERRKWIHCFESV
Sbjct:   160 IERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESV 219

Query:   181 TSIIFLVALSEYDQVLAESDNENRLEESKALFKTIITYPWFSNSSIILFLNKKDLLEEKI 240
             TSIIFLVALSEYDQVLAE DNENR+EESKALF+TIITYPWF NSS+ILFLNKKDLLEEKI
Sbjct:   220 TSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKI 279

Query:   241 MYSHLVTYFPQFTGPKQDVKAAKDFILNLYQEQNPDKEKVMYSHFTCATDTENIRFVFAA 300
             MYSHL++YFP++TGPKQDVKAA+DFIL LYQ+QNPDKEKV+YSHFTCATDTENIRFVFAA
Sbjct:   280 MYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAA 339

Query:   301 VKDTILNINLKEFNL 315
             VKDTIL +NL+EFNL
Sbjct:   340 VKDTILQLNLREFNL 354