| Nomenclature | Genomic Location |
| Symbol | Col3a1 | Chromosome | 1 |
| Name | Collagen alpha-1(III) chain | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | 1: 81 Mbp |
| Molecular Function |
|
Collagen type III occurs in most soft connective tissues along with type I collagen.
Molecular Function Terms:
binding
carbohydrate binding
polysaccharide binding
glycosaminoglycan binding
protein binding
glycoprotein binding
proteoglycan binding
structural molecule activity
extracellular matrix structural constituent
|
| Human Disease Association |
|
Defects in COL3A1 are a cause of Ehlers-Danlos syndrome type 3 (EDS3) [MIM:130020]; also known as
benign hypermobility syndrome. EDS is a connective tissue disorder characterized by hyperextensible
skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS3 is a form of
Ehlers-Danlos syndrome characterized by marked joint hyperextensibility without skeletal deformity.
Defects in COL3A1 are the cause of Ehlers-Danlos syndrome type 4 (EDS4) [MIM:130050]. EDS is a
connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to
tissue fragility and joint hyperlaxity. EDS4 is the most severe form of the disease. It is characterized
by the joint and dermal manifestations as in other forms of the syndrome, characteristic facial
features (acrogeria) in most patients, and by proneness to spontaneous rupture of bowel and large
arteries. The vascular complications may affect all anatomical areas.
Defects in COL3A1 are a cause of susceptibility to aortic aneurysm abdominal (AAA) [MIM:100070].
AAA is a common multifactorial disorder characterized by permanent dilation of the abdominal aorta,
usually due to degenerative changes in the aortic wall. Histologically, AAA is characterized by
signs of chronic inflammation, destructive remodeling of the extracellular matrix, and depletion of
vascular smooth muscle cells.
|
1 GTGTTGTCTTTTGTTTACATTTTATGGTTTTTTGTTTATACAAGCATTGAATATTTGTCT
61 GTTATTATGTTGGAAGCTGGCCTGAATCCCCATGGAGACTGTACCCACCTTGGCCAAGTG
121 TATGCTGACAGAGATGTGTGGAAACCGGAACCGTGCCAAATCTGTGTCTGCGACCAGGGA
181 TCTGTTCTTTGTGATGATATCATCTGTGACGAACAAGAATTAGACTGCCCCAATCCGGAG
241 ATTCCTTTTGGAGAATGTTGCCCAGTTTGTCCTCAGCTGACATCTCCGCCACCTTCTGGC
301 CCTTCTGTAAATGGTCCCCAAGGCCCCAGGGGAGATCCCGGTCCACCTGGCACTCCTGGA
361 AGAAATGGTTCACCTGGTCAACCCGGCCAACCGGGAATTCCTGGCAATCCAGGGCCCCCA
421 GGAGTCTGCCAAAATTGCCCCAGTTTGAATGGAGGTCAGGGCTATTCTCCTCAGTATGAG
481 GATGTCAAGGCTGGTGGTGGAGGAATGTACCCTGGCCCAATTTCTGCACCCGGAGCTCCT
541 GGCCCACCTGGGCTCCCTGGTCCTATTGGTCAGACCGGTCCACCTGGACCGCATGGATAT
601 CAAGGCCCTCCTGGTGAAAATGGACAACCTGGCAGTCCAGGCCCCGTTGGTCCACCAGGA
661 ATGATTGGTCCACCAGGCCCAGCTGGAAAAGATGGAGAATCTGGAAGACCCGGTAGACCT
721 GGTGAACGTGGATTGCCTGGACCTCCTGGCCATAAAGGTCCCTCTGGCATGCCAGGACTT
781 CCTGGAATGAAAGGTCATCGAAAGGGCTTTGATGGAAGAGATGGTGCAAAAGGTGATTCA
841 GGGGCTCCTGGTCTAAAGGGTGAAAATGGCCTTCCTGGAGAAAATGGATCCCCTGGACCA
901 ATGGGTCCAAGAGGTCAGCCAGGTGAAAGAGGAAGAGCAGGACTTCCAGGAACTGCCGGT
961 GCTCGTGGTAACGATGGAACTCCTGGAGCATCTGGCCAACCCGGTCCTCCAGGCCCTCCA
1021 GGACCATCAGGATTTCCAGGTTCTCCTGGTTTTAAGGGTGAAACAGGTTCTTCTGGACCA
1081 CCAGGCTCCAGTGGATCTCCTGGGCCAAGAGGAGAACCTGGCCCTCAAGGTGCTCCCGGT
1141 GGTGCTGGTCCTCCTGGTCCTGGTGGTCGAGATGGAAATCCAGGTGCAAAAGGTCTTCCA
1201 GGTTCGGCTGGCATGACTGGACCTCCTGGACTGAGTGGAGCTCGTGGACCTCCTGGCCCC
1261 GCTGGCACCAATGGGATCCCTGGACAAAGAGGCCCATCTGGTGAACCTGGCAAGAATGGT
1321 GCAAAAGGAGAGCCAGGACAAAGAGGTGAACGTGGTGAAAATGGCACTCCTGGTGCTGCT
1381 GGTCCTCCAGGGGAGGAAGGCAAGGCAGGAGCAGCTGGTCAACCTGGAACGAATGGCATA
1441 CCCGGAAGTCCCGGAGAAAGGGGTTCCCCAGGTTTCCGAGGTCCTGCTGGCAGTAACGGC
1501 CCTCCAGGTGAAAAGGGTGCCCCTGGTGAACGAGGTGGCCCAGGAGCTCCTGGACCCAGA
1561 GGTGTTCAGGGTGAATCAGGACGTGATGGGAGTCCCGGTCTTCCAGGAATGAGAGGTTTA
1621 ACAGGCAGCCCTGGAGCCCCAGGATCAGATGGAAAACCAGGCCCAGGGGGTCCACCAGGA
1681 GAATCTGGACGAAGTGGGCCCCCAGGTCCAGCAGGTCCACGGGGTCAACCAGGTGTGATG
1741 GGTTTTCCTGGTCCAAAGGGTAGTGAGGGTGCACCTGGTAAAAATGGAGAAAGGGGTTCT
1801 TCTGGACCTCCTGGTACACAGGGACCAGCTGGAAAGGATGGTGAAGCAGGAGCCCAAGGA
1861 CCTCCTGGACCTGGTGGTCCTCCTGGTGAAAAAGGAGACCAGGGAGCACCTGGGACACCT
1921 GGATTCCAGGGACTGCCTGGATCTCCAGGACCTGCTGGAGAGAATGGAAAGCCAGGAGAA
1981 GCAGGCCCAAGAGGTGAAAATGGAGGTCCAGGACTCCCAGGGTCCAAGGGTGAAAATGGC
2041 ATCCCCGGTGAACGAGGTGCACAAGGGCCTCCAGGTTCCCCTGGAACTAGAGGTAGTCCT
2101 GGCCCTACTGGACCAGAGGGTGGAAAAGGCCCTGCTGGCCCACCAGGACCTCCGGGCAAC
2161 ATGGGACCACCAGGTTTGCAAGGAATGCCTGGAGAGAGAGGAGGTTCTGGAAGTCCTGGA
2221 CCCAAGGGAGAGAAGGGAGAGCCTGGTGGCAGAGGTGGAGATGGCTTACCTGGTAAAGAT
2281 GGTGTGCGAGGTCCTGTAGGATCAATTGGACCCCCTGGTCCAGCTGGCCAACCTGGTGAC
2341 AAGGGAGAGCCTGGTCCAGCTGGACCTCATGGTCCAACAGGTGCACGCGGTGGTCCCGGT
2401 GATCGAGGTGAATCCGGCCCCCCTGGCCCTGCTGGCTTCCCTGGAGCTCCTGGACAAAAT
2461 GGAGAACCTGGTGGGAAAGGAGATAAAGGTCCTGCTGGTGAAAGAGGAGAACCTGGACCA
2521 CCTGGGGCTGCCGGTCCATCAGGAGGCCCTGGTGCACCAGGTCCTTCTGGTCCACAAGGT
2581 GGAAAAGGAGAGCGTGGTTCTCCAGGACCCGCAGGTCAGGCTGGCTTTCCTGGTGCTCGT
2641 GGCTTACCTGGTCCTCCTGGTAACAATGGAAACCCTGGACAACCAGGCAATGCAGGCCCT
2701 GCAGGCAAAGATGGACCCCCTGGTCCAGCTGGTTCTACTGGCCCCGTTGGTAGCCCAGGT
2761 GCTGCAGGTCCAAAAGGTGAGCCTGGTGTCCCAGGTGAAAAAGGCCCATCAGGTGCAAGA
2821 GGAGAACCAGGATCACCAGGTCCGTCCGGTATCTTGGGGCCACCAGGACAACGTGGTATT
2881 GTAGGATTGCCTGGCATGAGAGGTTTACCAGGACCTTCTGGTCTAAGCGGCCCAAGGGGT
2941 GAAGACGGAAAACCAGGATCAAATGGTAGCCCAGGAGAACGTGGACCTCCTGGTGCACAG
3001 GGTCCTCCTGGTATCAGTGGAACACCTGGAGAACCAGGCAGAGATGGCAACGCTGGATCA
3061 GATGGTTTACCAGGTCGTGATGGATCTTCAGGACCAAAGGGTGATCGTGGTGAAAATGGT
3121 TCACCTGGTTTACCAGGGGCTCCAGGTCATGTTGGTCCCCCAGGTAATAGCGGTCCTGCT
3181 GGAAAACCAGGTGACAGAGGACATCCAGGACCCGCTGGTCCAGTTGGCCCTTCAGGTCCT
3241 GCTGGTATACGGGGTGCTCCGGGTCCTGCTGGTGCGCGTGGGGATAAAGGTGAAGCTGGT
3301 GAACGTGGTCTCAATGGTATCAAAGGTCATCGAGGATTCCCTGGTAACCCAGGTCCTCCT
3361 GGTCCAGCGGGTGCACTGGGTCCCCAAGGTCCAAATGGAAGCCCAGGACCATCAGGTGCA
3421 AGAGGTCCCCCTGGACCAAGTGGTCCACCTGGAAAAGATGGTACAAGTGGTTATCCAGGT
3481 CCCATTGGTCCACCAGGTCCACGGGGCAGTCGAGGTGAAAGCGGAACTGCGGGTCCACCC
3541 GGTCATAGCGGTCCTCCAGGGCCTCCTGGTCAACCTGGAGCTCCTGGTCCTTGTTGTGGT
3601 GATGGTGCTGGTATGATGGGCCCAAGTGGTGAAAAAGGACCAAGCTACTACAGAGATGAG
3661 CCACCTGAGGACAGAATTGCCATGAGTGATGTTTTAACTTCATTAAAATCAATCAATAGC
3721 CAGATTGAAAACATCATCAGCCCAGATGGCACACGAAAGAATCCAGCCCGTAACTGCAGA
3781 GATCTCAAGTTCTGTCATCCTGACCTTAAGAGTGGAGAGTATTGGATTGATCCTAACCAA
3841 GGTTGCAAATTGGATGCTATTAAAGTATTCTGCAATATGGAAACTGGGGAGACGTGCATC
3901 AATGCCAGTCCTAAAGCTGTCCCAAAGAAGAGCTGGTGGGAAAGTCCAGGACCTGAAAAG
3961 AAACACGTTTGGTTTGGAGAGTCTATGAATGGAGGCTTCCAGTTCAACTACGGAGATCCA
4021 GATCTTCCAGAAGAAGTTGCAGATGTTCAACTCGCATTCCTCAGAATCCTCTCTAGTCGA
4081 GCCACACAGAATATCACCTATCACTGCAAGAACAGCATTGCTTATATGGATGAGGCGAGC
4141 GGGAATGTAAAGAGAGCCCTTAAACTAATGACTTCTACTGACAGTGAAATCAAGGCGGAA
4201 GGGAACAGCAAATTTACATACAGTGTCCTGGAAGATGGCTGCACTAAACACACTGATGAA
4261 TGGGGTAAAACAGTCTTCGAGTACAGAACACGCAAGACAATGAGATTGCCTATCATAGAT
4321 ATTGCACCCTTCGATATCGGCGCTCCCAATCAGGAATTTGGTGTGGACATTGGCCCAGTT
4381 TGCTTCTTATAA
| Predicted Protein Product |
VLSFVYILWFFVYTSIEYLSVIMLEAGLNPHGDCTHLGQVYADRDVWKPEPCQICVCDQG
SVLCDDIICDEQELDCPNPEIPFGECCPVCPQLTSPPPSGPSVNGPQGPRGDPGPPGTPG
RNGSPGQPGQPGIPGNPGPPGVCQNCPSLNGGQGYSPQYEDVKAGGGGMYPGPISAPGAP
GPPGLPGPIGQTGPPGPHGYQGPPGENGQPGSPGPVGPPGMIGPPGPAGKDGESGRPGRP
GERGLPGPPGHKGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGP
MGPRGQPGERGRAGLPGTAGARGNDGTPGASGQPGPPGPPGPSGFPGSPGFKGETGSSGP
PGSSGSPGPRGEPGPQGAPGGAGPPGPGGRDGNPGAKGLPGSAGMTGPPGLSGARGPPGP
AGTNGIPGQRGPSGEPGKNGAKGEPGQRGERGENGTPGAAGPPGEEGKAGAAGQPGTNGI
PGSPGERGSPGFRGPAGSNGPPGEKGAPGERGGPGAPGPRGVQGESGRDGSPGLPGMRGL
TGSPGAPGSDGKPGPGGPPGESGRSGPPGPAGPRGQPGVMGFPGPKGSEGAPGKNGERGS
SGPPGTQGPAGKDGEAGAQGPPGPGGPPGEKGDQGAPGTPGFQGLPGSPGPAGENGKPGE
AGPRGENGGPGLPGSKGENGIPGERGAQGPPGSPGTRGSPGPTGPEGGKGPAGPPGPPGN
MGPPGLQGMPGERGGSGSPGPKGEKGEPGGRGGDGLPGKDGVRGPVGSIGPPGPAGQPGD
KGEPGPAGPHGPTGARGGPGDRGESGPPGPAGFPGAPGQNGEPGGKGDKGPAGERGEPGP
PGAAGPSGGPGAPGPSGPQGGKGERGSPGPAGQAGFPGARGLPGPPGNNGNPGQPGNAGP
AGKDGPPGPAGSTGPVGSPGAAGPKGEPGVPGEKGPSGARGEPGSPGPSGILGPPGQRGI
VGLPGMRGLPGPSGLSGPRGEDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGS
DGLPGRDGSSGPKGDRGENGSPGLPGAPGHVGPPGNSGPAGKPGDRGHPGPAGPVGPSGP
AGIRGAPGPAGARGDKGEAGERGLNGIKGHRGFPGNPGPPGPAGALGPQGPNGSPGPSGA
RGPPGPSGPPGKDGTSGYPGPIGPPGPRGSRGESGTAGPPGHSGPPGPPGQPGAPGPCCG
DGAGMMGPSGEKGPSYYRDEPPEDRIAMSDVLTSLKSINSQIENIISPDGTRKNPARNCR
DLKFCHPDLKSGEYWIDPNQGCKLDAIKVFCNMETGETCINASPKAVPKKSWWESPGPEK
KHVWFGESMNGGFQFNYGDPDLPEEVADVQLAFLRILSSRATQNITYHCKNSIAYMDEAS
GNVKRALKLMTSTDSEIKAEGNSKFTYSVLEDGCTKHTDEWGKTVFEYRTRKTMRLPIID
IAPFDIGAPNQEFGVDIGPVCFL
| Protein Alignment to Mouse |
tr|Q7TT32|Q7TT32_MOUSE Collagen, type III, alpha 1 OS=Mus musculus GN=Col3a1
PE=2 SV=1
MGI:88457 Col5a1 collagen, type V, alpha 1 (Chr 2)
Length = 1464
Score = 1127 (401.8 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 200/255 (78%), Positives = 227/255 (89%)
Query: 1209 SGEKGPSYYRDEPPEDRIAMSDVLTSLKSINSQIENIISPDGTRKNPARNCRDLKFCHPD 1268
SG P YY D+P + +I ++++SLKS+N QIE++ISPDG+RKNPARNCRDLKFCHP+
Sbjct: 1211 SGGFSP-YYGDDPMDFKINTEEIMSSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPE 1269
Query: 1269 LKSGEYWIDPNQGCKLDAIKVFCNMETGETCINASPKAVPKKSWWESPGPEKKHVWFGES 1328
LKSGEYW+DPNQGCK+DAIKVFCNMETGETCINASP VP+K WW G EKKHVWFGES
Sbjct: 1270 LKSGEYWVDPNQGCKMDAIKVFCNMETGETCINASPMTVPRKHWWTDSGAEKKHVWFGES 1329
Query: 1329 MNGGFQFNYGDPDLPEEVADVQLAFLRILSSRATQNITYHCKNSIAYMDEASGNVKRALK 1388
MNGGFQF+YG PDLPE+V DVQLAFLR+LSSRA+QNITYHCKNSIAYMD+ASGNVK++LK
Sbjct: 1330 MNGGFQFSYGPPDLPEDVVDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKSLK 1389
Query: 1389 LMTSTDSEIKAEGNSKFTYSVLEDGCTKHTDEWGKTVFEYRTRKTMRLPIIDIAPFDIGA 1448
LM S + E KAEGNSKFTY+VLEDGCTKHT EW KTVFEY+TRK MRLPIIDIAP+DIG
Sbjct: 1390 LMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYQTRKAMRLPIIDIAPYDIGG 1449
Query: 1449 PNQEFGVDIGPVCFL 1463
P+QEFGVDIGPVCFL
Sbjct: 1450 PDQEFGVDIGPVCFL 1464
Score = 439 (159.6 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 84/133 (63%), Positives = 87/133 (65%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
E GKPG++G GERGPPG QG PG GT GEPGRDGN GSDG PGRDGS G KGDRGENG
Sbjct: 978 ESGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENG 1037
Query: 1041 SPGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEAG 1100
SPG PGAPGH GPPG GP+GK GDRG DKGE G
Sbjct: 1038 SPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETG 1097
Query: 1101 ERGLNGIKGHRGF 1113
ERG NGIKGHRGF
Sbjct: 1098 ERGSNGIKGHRGF 1110
Score = 353 (129.3 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 62/74 (83%), Positives = 68/74 (91%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KGP+GMPG PGMKGHR GFDGR+G KG++GAPGLKGENGLPG+NG+PGPMGPRG PGERG
Sbjct: 250 KGPAGMPGFPGMKGHR-GFDGRNGEKGETGAPGLKGENGLPGDNGAPGPMGPRGAPGERG 308
Query: 312 RAGLPGTAGARGND 325
R GLPG AGARGND
Sbjct: 309 RPGLPGAAGARGND 322
Score = 353 (129.3 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 73/140 (52%), Positives = 79/140 (56%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G AG+ G PGL GARGPPGPAGTNGIPG RGPSGEPGKNGAKGEPG RGER
Sbjct: 398 GPAGIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIP 457
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXXX 520
NG+PG+ GERG GFRGPAG N
Sbjct: 458 GPKGEDGKDGSPGEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPR 517
Query: 521 XVQGESGRDGSPGLPGMRGL 540
V GE GRDG+PG PG+RG+
Sbjct: 518 GVAGEPGRDGTPGGPGIRGM 537
Score = 329 (120.9 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 61/108 (56%), Positives = 68/108 (62%)
Query: 579 VMGFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPG 638
VMGFPGPKG++GAPGKNGERG G PG GPAGK PG
Sbjct: 576 VMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGETGPQGPPGPTGPAGDKGDSGPPG 635
Query: 639 TPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G QG+PG+ GP GENGKPGE GP+GE G PG PG KG++G PGERG
Sbjct: 636 PQGLQGIPGTGGPPGENGKPGEPGPKGEVGAPGAPGGKGDSGAPGERG 683
Score = 328 (120.5 bits), Expect = 6.5e-298, Sum P(6) = 6.5e-298
Identities = 56/92 (60%), Positives = 70/92 (76%)
Query: 1 VLSFVYILWFFVYTSIEYLSVIMLEAGLNPHGDCTHLGQVYADRDVWKPEPCQICVCDQG 60
++SFV +F+ T + ++ ++ ++ G C+HLGQ Y RDVWKPEPCQICVCD G
Sbjct: 1 MMSFVQSGTWFLLTLLHPTLILAQQSNVDELG-CSHLGQSYESRDVWKPEPCQICVCDSG 59
Query: 61 SVLCDDIICDEQELDCPNPEIPFGECCPVCPQ 92
SVLCDDIICDE+ LDCPNPEIPFGECC +CPQ
Sbjct: 60 SVLCDDIICDEEPLDCPNPEIPFGECCAICPQ 91
Score = 254 (94.5 bits), Expect = 1.6e-183, Sum P(4) = 1.6e-183
Identities = 56/133 (42%), Positives = 61/133 (45%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG G PG G PG+ G PG G PGEPG+ G AG G PG G +GP G GE+G P
Sbjct: 176 GPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGESGRP 235
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGD---RGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEA 1099
G PG G GPPG GPAG PG +GH D G
Sbjct: 236 GRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGDNGAP 295
Query: 1100 GERGLNGIKGHRG 1112
G G G G RG
Sbjct: 296 GPMGPRGAPGERG 308
Score = 238 (88.8 bits), Expect = 9.1e-277, Sum P(6) = 9.1e-277
Identities = 59/151 (39%), Positives = 69/151 (45%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKG-------- 1034
G PG++GSPG +G PG +G PG G GE G G AG+DG+PG+DG GP G
Sbjct: 713 GPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPA 772
Query: 1035 ----DRGENGSPGLPG--AP-------GHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXX 1081
D+GE GSPGLPG P G GPPG +G G PG G
Sbjct: 773 GQPGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEK 832
Query: 1082 XXXXXXXXXXXXXDKGEAGERGLNGIKGHRG 1112
G AG G G+KG RG
Sbjct: 833 GEGGPPGPAGPTGSSGPAGPPGPQGVKGERG 863
Score = 238 (88.8 bits), Expect = 1.0e-202, Sum P(5) = 1.0e-202
Identities = 55/132 (41%), Positives = 61/132 (46%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
E+G PG NG+PG GP GA PG G PG PG G G+DG G DG GP G G G
Sbjct: 285 ENGLPGDNGAPGPMGPRGA---PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG 341
Query: 1041 SPGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEAG 1100
PG PGA G VGP G+ G G PG RG + G AG
Sbjct: 342 FPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAG 401
Query: 1101 ERGLNGIKGHRG 1112
G G+ G RG
Sbjct: 402 IPGAPGLIGARG 413
Score = 236 (88.1 bits), Expect = 1.5e-276, Sum P(6) = 1.5e-276
Identities = 55/133 (41%), Positives = 62/133 (46%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGT---PGEPGRDGNAGSDGLPGRDGSSGPKGDRGEN 1039
G G G PGE+GPPGAQGPPG G G G G AG G+PG GS GP+G +GE+
Sbjct: 920 GPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGES 979
Query: 1040 GSPGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEA 1099
G PG G G GPPG G G+PG G D+GE
Sbjct: 980 GKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKG---DRGEN 1036
Query: 1100 GERGLNGIKGHRG 1112
G G G GH G
Sbjct: 1037 GSPGAPGAPGHPG 1049
Score = 234 (87.4 bits), Expect = 1.1e-226, Sum P(5) = 1.1e-226
Identities = 46/88 (52%), Positives = 53/88 (60%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISG---TPGEPGRDGNAGSDGLPGRDGSSGPKGDRGEN 1039
G G NG PGE+GPPG +G PG +G GEPGRDG G G+ G GS G G+ G+
Sbjct: 491 GPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKP 550
Query: 1040 GSPGLPGAPGHVGPPGNSGPAGKPGDRG 1067
G PG G G GPPG SGP G+PG G
Sbjct: 551 GPPGSQGESGRPGPPGPSGPRGQPGVMG 578
Score = 234 (87.4 bits), Expect = 1.8e-206, Sum P(4) = 1.8e-206
Identities = 55/139 (39%), Positives = 65/139 (46%)
Query: 983 GKPGSNGSPGERGPPG------AQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDR 1036
G PGSNGSPG+RG PG AQGPPG G G PG G G G+PG G G +G
Sbjct: 356 GSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPP 415
Query: 1037 GENGSPGLPGAPGHVGPPGNSGPAGKPG---DRGHXXXXXXXXXXXXXXXXXXXXXXXXX 1093
G G+ G+PG G G PG +G G+PG +RG
Sbjct: 416 GPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGAN 475
Query: 1094 XDKGEAGERGLNGIKGHRG 1112
G AGERG +G +G G
Sbjct: 476 GLPGAAGERGPSGFRGPAG 494
Score = 233 (87.1 bits), Expect = 4.3e-261, Sum P(6) = 4.3e-261
Identities = 54/136 (39%), Positives = 64/136 (47%)
Query: 983 GKPGSNGSPGERGP---PGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGEN 1039
G G +G PG +G PG GPPG +G PGEPG G G+ G PG G SG G+RG
Sbjct: 626 GDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEVGAPGAPGGKGDSGAPGERGPP 685
Query: 1040 GSPGLPGAPGHVGPPG---NSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDK 1096
G+ G+PGA G GPPG GPAG PG G +K
Sbjct: 686 GTAGIPGARGGAGPPGPEGGKGPAGPPGPPG---ASGSPGLQGMPGERGGPGSPGPKGEK 742
Query: 1097 GEAGERGLNGIKGHRG 1112
GE G G +G+ G G
Sbjct: 743 GEPGGAGADGVPGKDG 758
Score = 232 (86.7 bits), Expect = 3.9e-276, Sum P(6) = 3.9e-276
Identities = 46/91 (50%), Positives = 54/91 (59%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGS---SGPKGDRG 1037
E+G PG+ G+PG GPPG GP G SG GE G G +G+ G G G+ GP+GD+G
Sbjct: 1035 ENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKG 1094
Query: 1038 ENGSPGLPGAPGHVGPPGNSGPAGKPGDRGH 1068
E G G G GH G PGN GP G PG GH
Sbjct: 1095 ETGERGSNGIKGHRGFPGNPGPPGSPGAAGH 1125
Score = 231 (86.4 bits), Expect = 5.0e-276, Sum P(6) = 5.0e-276
Identities = 56/142 (39%), Positives = 64/142 (45%)
Query: 983 GKPGSNGSPGERGPPGAQGP---PGISGTPGEPGRDGNAGS---DGLPGRDGSSGPKGDR 1036
G PG G GERG PG G PG G PG PG +GN G G PG+DG GP G+
Sbjct: 851 GPPGPQGVKGERGSPGGPGTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNS 910
Query: 1037 GENGSPGL--P----GAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXX 1090
G G+PG+ P G PG GPPG GP G PG G
Sbjct: 911 GSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSP 970
Query: 1091 XXXXDKGEAGERGLNGIKGHRG 1112
KGE+G+ G +G G RG
Sbjct: 971 GPQGIKGESGKPGASGHNGERG 992
Score = 231 (86.4 bits), Expect = 6.9e-261, Sum P(6) = 6.9e-261
Identities = 60/144 (41%), Positives = 65/144 (45%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGE---------PGRDGNAGSDGLPGRDGSSG 1031
E+GKPG G GE G PGA G G SG PGE PG G AG G G G +G
Sbjct: 651 ENGKPGEPGPKGEVGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGKGPAG 710
Query: 1032 PKGDRGENGSPGLPGAPGHVGPPGNSGPAGK---PGDRGHXXXXXXXXXXXXXXXXXXXX 1088
P G G +GSPGL G PG G PG+ GP G+ PG G
Sbjct: 711 PPGPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPG 770
Query: 1089 XXXXXXDKGEAGERGLNGIKGHRG 1112
DKGE G GL GI G RG
Sbjct: 771 PAGQPGDKGEGGSPGLPGIAGPRG 794
Score = 231 (86.4 bits), Expect = 2.2e-226, Sum P(5) = 2.2e-226
Identities = 49/96 (51%), Positives = 53/96 (55%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
E G PG G PG GP G G PG GTPG PG G GS G PG DG GP G +GE+G
Sbjct: 501 EKGPPGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPPGSQGESG 560
Query: 1041 SPGLPGA------PGHVG---PPGNSGPAGKPGDRG 1067
PG PG PG +G P GN G GK G+RG
Sbjct: 561 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERG 596
Score = 230 (86.0 bits), Expect = 6.3e-276, Sum P(6) = 6.3e-276
Identities = 52/135 (38%), Positives = 62/135 (45%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
E G G++G PG+ GP G GP G G G+PG G GS GLPG G G G+RGE+G
Sbjct: 744 EPGGAGADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGGSPGLPGIAGPRGGPGERGEHG 803
Query: 1041 SPG---LPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKG 1097
PG PGAPG G PG G G PG++G ++G
Sbjct: 804 PPGPAGFPGAPGQNGEPGAKGERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGVKGERG 863
Query: 1098 EAGERGLNGIKGHRG 1112
G G G G RG
Sbjct: 864 SPGGPGTAGFPGGRG 878
Score = 227 (85.0 bits), Expect = 9.9e-206, Sum P(4) = 9.9e-206
Identities = 54/133 (40%), Positives = 67/133 (50%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PGS G+ GE GP G+ G G G GEPG G+AG+ G PG G++G G +GE G
Sbjct: 341 GFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPA 400
Query: 1043 GLPGAPGHVG---PPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEA 1099
G+PGAPG +G PPG +G G PG RG ++GEA
Sbjct: 401 GIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARG---------ERGEA 451
Query: 1100 GERGLNGIKGHRG 1112
G G+ G KG G
Sbjct: 452 GSPGIPGPKGEDG 464
Score = 225 (84.3 bits), Expect = 2.1e-275, Sum P(6) = 2.1e-275
Identities = 55/139 (39%), Positives = 62/139 (44%)
Query: 983 GKPGSNGSPGERGP---PGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGEN 1039
G PG+NG+PG GP PG GPPG +G G PG G AG G G+ G GP G +G
Sbjct: 881 GPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPP 940
Query: 1040 GSPG------LPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXX 1093
GSPG L GA G GPPG GP G PG +G
Sbjct: 941 GSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLP 1000
Query: 1094 XDKGEAGERGLNGIKGHRG 1112
G AGE G +G G G
Sbjct: 1001 GQPGTAGEPGRDGNPGSDG 1019
Score = 223 (83.6 bits), Expect = 1.6e-225, Sum P(5) = 1.6e-225
Identities = 50/97 (51%), Positives = 58/97 (59%)
Query: 983 GKPGSNGSPG---ERGPPGAQGP------PGISGTPGEPGRDGNAGSDGL---PGRDGSS 1030
G+PG+NG PG ERGP G +GP PG G PGE G G AG G+ PGRDG+
Sbjct: 470 GEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGTP 529
Query: 1031 GPKGDRGENGSPGLPGAPGHVGPPGNSGPAGKPGDRG 1067
G G RG GSPG PG G GPPG+ G +G+PG G
Sbjct: 530 GGPGIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPG 566
Score = 223 (83.6 bits), Expect = 2.6e-205, Sum P(4) = 2.6e-205
Identities = 51/131 (38%), Positives = 57/131 (43%)
Query: 982 DGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGS 1041
DG GS+G PG GPPG G PG G GE G G+ GS+G PG+ G GP+G G G
Sbjct: 322 DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGP 381
Query: 1042 PGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEAGE 1101
PG PG G G G GPAG PG G G GE
Sbjct: 382 PGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEPGKNGAKGE 441
Query: 1102 RGLNGIKGHRG 1112
G G +G G
Sbjct: 442 PGARGERGEAG 452
Score = 222 (83.2 bits), Expect = 4.4e-275, Sum P(6) = 4.4e-275
Identities = 52/139 (37%), Positives = 59/139 (42%)
Query: 983 GKPGSNGSPGERGPPGA------QGPPGISGTPGEPGRDGNAGSDGLPGRDGS---SGPK 1033
G PG G GE G PGA +GPPG G PG+PG G G DG PG DG G
Sbjct: 968 GSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSP 1027
Query: 1034 GDRGENGSPGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXX 1093
G +G+ G G PGAPG G PG GP G G G
Sbjct: 1028 GGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQ 1087
Query: 1094 XDKGEAGERGLNGIKGHRG 1112
+G+ GE G G G +G
Sbjct: 1088 GPRGDKGETGERGSNGIKG 1106
Score = 221 (82.9 bits), Expect = 1.4e-224, Sum P(5) = 1.4e-224
Identities = 45/88 (51%), Positives = 50/88 (56%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G G+NG PG RGP G G G G PG G G AGS G+PG G G G GE G+
Sbjct: 416 GPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGAN 475
Query: 1043 GLPGAPGHVGPPGNSGPAGK---PGDRG 1067
GLPGA G GP G GPAG PG++G
Sbjct: 476 GLPGAAGERGPSGFRGPAGPNGIPGEKG 503
Score = 219 (82.2 bits), Expect = 5.3e-241, Sum P(5) = 5.3e-241
Identities = 53/131 (40%), Positives = 57/131 (43%)
Query: 982 DGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGS 1041
DGKPG GS GE G PG GP G G PG G G G+DG PG++G G G G G
Sbjct: 547 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGP 606
Query: 1042 PGLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEAGE 1101
G G G GPPG +GPAG GD G KGE G
Sbjct: 607 AGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEVGA 666
Query: 1102 RGLNGIKGHRG 1112
G G KG G
Sbjct: 667 PGAPGGKGDSG 677
Score = 219 (82.2 bits), Expect = 1.6e-185, Sum P(4) = 1.6e-185
Identities = 56/141 (39%), Positives = 65/141 (46%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
+DG+ G G PGERG PG G G +G PG PG G+ G DG G G +G G +GENG
Sbjct: 228 KDGESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENG 287
Query: 1041 SPGLPGAPGHVGPPGNSGPAGKPG------DRGHXXXXXXXXXXXXXXXXXXXXXXXXXX 1094
PG GAPG +GP G G G+PG RG+
Sbjct: 288 LPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG 347
Query: 1095 DKGE---AGERGLNGIKGHRG 1112
KGE AG G NG G RG
Sbjct: 348 AKGEVGPAGSPGSNGSPGQRG 368
Score = 215 (80.7 bits), Expect = 2.4e-274, Sum P(6) = 2.4e-274
Identities = 48/130 (36%), Positives = 57/130 (43%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG NG PG +G GA G G G PG G G++G G PG G G +G G G+
Sbjct: 812 GAPGQNGEPGAKGERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGPGTA 871
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDRGHXXXXXXXXXXXXXXXXXXXXXXXXXXDKGEAGER 1102
G PG G GPPGN+G G PG G D G+ GE+
Sbjct: 872 GFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEK 931
Query: 1103 GLNGIKGHRG 1112
G G +G G
Sbjct: 932 GPPGAQGPPG 941
Score = 215 (80.7 bits), Expect = 1.4e-240, Sum P(5) = 1.4e-240
Identities = 41/85 (48%), Positives = 46/85 (54%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG G+ G+ GPPG+QG G G PG G G G G PG G+ G G GE G P
Sbjct: 539 GSPGGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 598
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDRG 1067
G PG PG G G +GP G PG G
Sbjct: 599 GGPGLPGPAGKNGETGPQGPPGPTG 623
Score = 215 (80.7 bits), Expect = 1.7e-224, Sum P(5) = 1.7e-224
Identities = 46/93 (49%), Positives = 53/93 (56%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAG---SDGLPGRDGSSGPKGDRG 1037
E GK G+ G PG RG G G PGI G GE G+DG+ G ++GLPG G GP G RG
Sbjct: 432 EPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAGERGPSGFRG 491
Query: 1038 E---NGSPGLPGAPGHVGPPGNSGPAGKPGDRG 1067
NG PG G PG G PG +GP G G+ G
Sbjct: 492 PAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPG 524
Score = 213 (80.0 bits), Expect = 7.5e-224, Sum P(5) = 7.5e-224
Identities = 51/116 (43%), Positives = 54/116 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PGP GS G PG G G GPPG G AG PG P
Sbjct: 179 GPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGESGRPGRP 238
Query: 641 GFQGLPGSPG---PAGENGKPGEAGPRG------ENGGPGLPGSKGENGIPGERGA 687
G +GLPG PG PAG G PG G RG E G G PG KGENG+PG+ GA
Sbjct: 239 GERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGDNGA 294
Score = 212 (79.7 bits), Expect = 1.3e-285, Sum P(6) = 1.3e-285
Identities = 48/107 (44%), Positives = 52/107 (48%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PGPKG GAPG G +G SG PG +GP G PG
Sbjct: 656 GEPGPKGEVGAPGAPGGKGDSGAPGERGPPG------------TAGIPGARGGAGPPGPE 703
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERGA 687
G +G G PGP G +G PG G GE GGPG PG KGE G PG GA
Sbjct: 704 GGKGPAGPPGPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAGA 750
Score = 212 (79.7 bits), Expect = 5.0e-274, Sum P(6) = 5.0e-274
Identities = 43/88 (48%), Positives = 49/88 (55%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
+DG PG G+ G G PG GP G +G PGE G G G G PG G +G G RG G
Sbjct: 900 KDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAG 959
Query: 1041 SPGLPGAPGHVGPPGNSGPAGKPGDRGH 1068
PG+PG G GP G G +GKPG GH
Sbjct: 960 PPGMPGPRGSPGPQGIKGESGKPGASGH 987
Score = 212 (79.7 bits), Expect = 3.1e-168, Sum P(3) = 3.1e-168
Identities = 57/158 (36%), Positives = 64/158 (40%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPG---------------------RDGNAGSD 1021
G PG G PG G PG G PG+ G PG PG + G G
Sbjct: 110 GDPGPPGIPGRNGDPGLPGQPGLPGPPGSPGICESCPTGGQNYSPQFDSYDVKSGVGGMG 169
Query: 1022 GLPGRDGSSGPKGDRGENGSPGLPGAPGHVGPPGN---SGPAGKPGDRGHXXXXXXXXXX 1078
G PG G GP G G +G PG PG+PG+ GPPG +GPAG PG G
Sbjct: 170 GYPGPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKD 229
Query: 1079 XXXXXXXXXXXXXXXXD---KGEAGERGLNGIKGHRGF 1113
KG AG G G+KGHRGF
Sbjct: 230 GESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGF 267
Score = 206 (77.6 bits), Expect = 5.7e-285, Sum P(6) = 5.7e-285
Identities = 47/109 (43%), Positives = 51/109 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG KG G PG G GSSGP G GP G PG P
Sbjct: 827 GAPGEKGEGGPPGPAGPTGSSGPAGPPGPQG---VKGERGSPGGPGTAGFPGGRGLPGPP 883
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPG---SKGENGIPGERG 686
G G PG PGP+G GK G GP G +G PG PG KG+ G PGE+G
Sbjct: 884 GNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKG 932
Score = 206 (77.6 bits), Expect = 3.6e-244, Sum P(6) = 3.6e-244
Identities = 44/91 (48%), Positives = 49/91 (53%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGI---SGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGEN 1039
G G NG G +GPPG GP G SG PG G G G+ G PG +G G G +GE
Sbjct: 605 GPAGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEV 664
Query: 1040 GSPGLPGAPGHVGPPGNSGP---AGKPGDRG 1067
G+PG PG G G PG GP AG PG RG
Sbjct: 665 GAPGAPGGKGDSGAPGERGPPGTAGIPGARG 695
Score = 205 (77.2 bits), Expect = 7.2e-285, Sum P(6) = 7.2e-285
Identities = 44/109 (40%), Positives = 47/109 (43%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
GFPG G G PG GERG+ G G GP G +PG P
Sbjct: 809 GFPGAPGQNGEPGAKGERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGP 868
Query: 641 GFQGLPGS---PGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G PG PGP G NG PG GP G G G PG G +G PG G
Sbjct: 869 GTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPG 917
Score = 205 (77.2 bits), Expect = 2.7e-273, Sum P(6) = 2.7e-273
Identities = 41/82 (50%), Positives = 43/82 (52%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG GSPG G GA G PG +G G G G G DG G G GP G RG G
Sbjct: 1112 GNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGER 1171
Query: 1043 GLPGAPGHVGPPGNSGPAGKPG 1064
G G+PGH G PG GP G PG
Sbjct: 1172 GSEGSPGHPGQPGPPGPPGAPG 1193
Score = 204 (76.9 bits), Expect = 5.8e-244, Sum P(6) = 5.8e-244
Identities = 40/85 (47%), Positives = 47/85 (55%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G G G G+ GPPG QG GI GT G PG +G G G G G+ G G +G++G+P
Sbjct: 620 GPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEVGAPGAPGGKGDSGAP 679
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDRG 1067
G G PG G PG G AG PG G
Sbjct: 680 GERGPPGTAGIPGARGGAGPPGPEG 704
Score = 203 (76.5 bits), Expect = 4.4e-273, Sum P(6) = 4.4e-273
Identities = 40/85 (47%), Positives = 45/85 (52%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G G G GERG G +G G G PG PG G AG G G G +GP+G G +G P
Sbjct: 1088 GPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPP 1147
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDRG 1067
G G GH GP G GP G G+RG
Sbjct: 1148 GKDGTSGHPGPIGPPGPRGNRGERG 1172
Score = 203 (76.5 bits), Expect = 4.4e-273, Sum P(6) = 4.4e-273
Identities = 55/154 (35%), Positives = 64/154 (41%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGT---------PGEPGRDGNAGSDGLPGRDGSSGPK 1033
G+PG G PG +GPPG+ GP GI+G PG PG G+ G G+ G G G
Sbjct: 926 GQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGAS 985
Query: 1034 GDRGENGSPG---LPGAPGHVGPPG---NSGPAGKPG---------DRGHXXXXXXXXXX 1078
G GE G PG LPG PG G PG N G G+PG DRG
Sbjct: 986 GHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAP 1045
Query: 1079 XXXXXXXXXXXXXXXXDKGEAGERGLNGIKGHRG 1112
D+GE G G +G G G
Sbjct: 1046 GHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAG 1079
Score = 203 (76.5 bits), Expect = 2.2e-248, Sum P(5) = 2.2e-248
Identities = 44/106 (41%), Positives = 49/106 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG +G G PGKNG +G G G +G AG PG
Sbjct: 422 GIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAA 481
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G +G G GPAG NG PGE GP GE GGPG G +G G PG G
Sbjct: 482 GERGPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDG 527
Score = 203 (76.5 bits), Expect = 7.4e-244, Sum P(6) = 7.4e-244
Identities = 39/85 (45%), Positives = 47/85 (55%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG G G+ G G QGPPG +G G+ G G G GL G G+ GP G+ G+ G P
Sbjct: 599 GGPGLPGPAGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEP 658
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDRG 1067
G G G G PG G +G PG+RG
Sbjct: 659 GPKGEVGAPGAPGGKGDSGAPGERG 683
Score = 202 (76.2 bits), Expect = 5.0e-282, Sum P(6) = 5.0e-282
Identities = 51/144 (35%), Positives = 57/144 (39%)
Query: 400 PGSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXX 459
PG+AG G PG G GP G G+NG PGQRG G G GA+G PG G
Sbjct: 337 PGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGE 396
Query: 460 XXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGS---NXXXXXXXXXXXXXXXXX 516
G PG G G PG RGP+G N
Sbjct: 397 MGPAGIPGAPGLIGA---RGPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGS 453
Query: 517 XXXXXVQGESGRDGSPGLPGMRGL 540
+GE G+DGSPG PG GL
Sbjct: 454 PGIPGPKGEDGKDGSPGEPGANGL 477
Score = 202 (76.2 bits), Expect = 1.1e-268, Sum P(6) = 1.1e-268
Identities = 44/109 (40%), Positives = 51/109 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
GF GP G G PG+ G G G PG GP G +PG P
Sbjct: 488 GFRGPAGPNGIPGEKGPPGERGGPGPAGPRG---VAGEPGRDGTPGGPGIRGMPGSPGGP 544
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGL---PGSKGENGIPGERG 686
G G PG PG GE+G+PG GP G G PG+ PG KG +G PG+ G
Sbjct: 545 GNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 593
Score = 201 (75.8 bits), Expect = 7.1e-273, Sum P(6) = 7.1e-273
Identities = 39/77 (50%), Positives = 44/77 (57%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G PG+ G G G PG GP G G G PG+DG +G G G G G +G+RG GSP
Sbjct: 1118 GSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1177
Query: 1043 GLPGAPGHVGPPGNSGP 1059
G PG PG GPPG GP
Sbjct: 1178 GHPGQPGPPGPPGAPGP 1194
Score = 200 (75.5 bits), Expect = 2.4e-284, Sum P(6) = 2.4e-284
Identities = 46/106 (43%), Positives = 55/106 (51%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G++G PGK+G RG +GP G GPAG+ +PG P
Sbjct: 743 GEPGGAGADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGG---------------SPGLP 787
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G G PG GE+G PG AG G G G PG+KGE G PGE+G
Sbjct: 788 GIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEKG 833
Score = 200 (75.5 bits), Expect = 4.7e-248, Sum P(5) = 4.7e-248
Identities = 48/109 (44%), Positives = 50/109 (45%)
Query: 581 GFPGPKGS---EGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAP 637
G PG KG G+PG NG G G PG QG AG P
Sbjct: 344 GSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIP 403
Query: 638 GTPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G PG G G PGPAG NG PG GP GE PG G+KGE G GERG
Sbjct: 404 GAPGLIGARGPPGPAGTNGIPGTRGPSGE---PGKNGAKGEPGARGERG 449
Score = 199 (75.1 bits), Expect = 1.3e-259, Sum P(6) = 1.3e-259
Identities = 43/108 (39%), Positives = 49/108 (45%)
Query: 579 VMGFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPG 638
+ G G +G G PG G RGS GP G +G +GK G
Sbjct: 948 IAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAG 1007
Query: 639 TPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
PG G PGS G G +G PG G RGENG PG PG+ G G PG G
Sbjct: 1008 EPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1055
Score = 196 (74.1 bits), Expect = 1.2e-247, Sum P(5) = 1.2e-247
Identities = 48/119 (40%), Positives = 54/119 (45%)
Query: 581 GFPGPKGS---EGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAP 637
G PG GS G PG G G+ GPPG G G P
Sbjct: 356 GSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPP 415
Query: 638 GTPGFQGLPGSPGPAGENGK------PGEAGPRGENGGPGLPGSKGENG---IPGERGA 687
G G G+PG+ GP+GE GK PG G RGE G PG+PG KGE+G PGE GA
Sbjct: 416 GPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGA 474
Score = 195 (73.7 bits), Expect = 1.6e-247, Sum P(5) = 1.6e-247
Identities = 46/115 (40%), Positives = 51/115 (44%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G G +G++GA G +G+ G GPPGT G G PG
Sbjct: 314 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQ 373
Query: 641 GFQGLPGSPGPAGENGKPG---EAGPRGENGGPGL------PGSKGENGIPGERG 686
G G G PGP G NG PG E GP G G PGL PG G NGIPG RG
Sbjct: 374 GHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPPGPAGTNGIPGTRG 428
Score = 194 (73.4 bits), Expect = 3.9e-272, Sum P(6) = 3.9e-272
Identities = 42/91 (46%), Positives = 46/91 (50%)
Query: 981 EDGKPGSNGSPGE---RGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRG 1037
E G G +G+PG RG PG QGP G G GE G +G G G PG G G G G
Sbjct: 1065 ETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAG 1124
Query: 1038 ENGSPGLPGAPGHVGPPGNSGPAGKPGDRGH 1068
G+ G PG G GP G GP GK G GH
Sbjct: 1125 HQGAIGSPGPAGPRGPVGPHGPPGKDGTSGH 1155
Score = 194 (73.4 bits), Expect = 2.0e-247, Sum P(5) = 2.0e-247
Identities = 46/109 (42%), Positives = 52/109 (47%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G GA G G G++G PGT+GP+G+ PG
Sbjct: 401 GIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPK 460
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENG--GPGLP-GSKGENGIPGERG 686
G G GSPG G NG PG AG RG +G GP P G GE G PGERG
Sbjct: 461 GEDGKDGSPGEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKGPPGERG 509
Score = 194 (73.4 bits), Expect = 2.0e-247, Sum P(5) = 2.0e-247
Identities = 45/112 (40%), Positives = 50/112 (44%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAG---KXXXXXXXXXXXXXXXXXXXXXXXAP 637
G PG G++G PG GERG +G PG GP G K
Sbjct: 431 GEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAGERGPSGFR 490
Query: 638 GTPGFQGLPGSPGPAGENGKPGEAGPRGENGGPG---LPGSKGENGIPGERG 686
G G G+PG GP GE G PG AGPRG G PG PG G G+PG G
Sbjct: 491 GPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPG 542
Score = 193 (73.0 bits), Expect = 4.9e-272, Sum P(6) = 4.9e-272
Identities = 42/88 (47%), Positives = 47/88 (53%)
Query: 981 EDGKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENG 1040
E G+ GSNG G RG PG GPPG +PG G G GS G G G GP G G++G
Sbjct: 1095 ETGERGSNGIKGHRGFPGNPGPPG---SPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDG 1151
Query: 1041 SPGLPGAPGHVGPPGNSGPAGKPGDRGH 1068
+ G PG G GP GN G G G GH
Sbjct: 1152 TSGHPGPIGPPGPRGNRGERGSEGSPGH 1179
Score = 192 (72.6 bits), Expect = 1.0e-261, Sum P(6) = 1.0e-261
Identities = 46/110 (41%), Positives = 50/110 (45%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G G G G RG +GPPG GP G G P
Sbjct: 938 GPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGER---GPP 994
Query: 641 GFQGLPGSPGPAGE---NGKPGEAGPRGENGGPGLPGSKGENGIPGERGA 687
G QGLPG PG AGE +G PG G G +G PG G +GENG PG GA
Sbjct: 995 GPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGA 1044
Score = 192 (72.6 bits), Expect = 4.5e-238, Sum P(6) = 4.5e-238
Identities = 47/118 (39%), Positives = 50/118 (42%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG KG G PG NG G GP G G G+ PG P
Sbjct: 278 GAPGLKGENGLPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 337
Query: 641 GFQGLPGSPG------PAGE---NGKPG---EAGPRGENGGPGLPGSKGENGIPGERG 686
G G PGSPG PAG NG PG E GP+G G G PG G NG PG +G
Sbjct: 338 GTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKG 395
Score = 192 (72.6 bits), Expect = 8.5e-225, Sum P(5) = 8.5e-225
Identities = 46/110 (41%), Positives = 51/110 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G G G G PG+ GERG GPPG +GPAG APG
Sbjct: 224 GPAGKDGESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLK 283
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRG---ENGGPGLPGSKGENGIPGERGA 687
G GLPG +NG PG GPRG E G PGLPG+ G G G RG+
Sbjct: 284 GENGLPG------DNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 327
Score = 191 (72.3 bits), Expect = 4.1e-247, Sum P(5) = 4.1e-247
Identities = 52/144 (36%), Positives = 59/144 (40%)
Query: 399 LPGSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXX 458
LPG AG G PG G GPPGPAG G PGQ +GEPG G +G PG++GE
Sbjct: 786 LPGIAGPRGGPGERGEHGPPGPAGFPGAPGQ---NGEPGAKGERGAPGEKGEGGPPGPAG 842
Query: 459 XXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRG---PAGSNXXXXXXXXXXXXXXXX 515
G PG PG G PG RG P G+N
Sbjct: 843 PTGSSGPAGPPGPQGVKGERGSPGGPGTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDG 902
Query: 516 XXXXXXVQGESGRDGSPGLPGMRG 539
G +G GSPG PG+ G
Sbjct: 903 P------PGPAGNSGSPGNPGIAG 920
Score = 191 (72.3 bits), Expect = 8.3e-241, Sum P(6) = 8.3e-241
Identities = 51/149 (34%), Positives = 60/149 (40%)
Query: 400 PGSAGMTGPPGLSGARGPPGPAGT---NGIPGQRGPSGEPGKNGA---KGEPGQRGERXX 453
PG G+ GPPG +G GPPGP+G +G PG G SG PG G KG+ GQ GE+
Sbjct: 874 PGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGP 933
Query: 454 XXXXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPG---FRGPAGSNXXXXXXXXXXX 510
G PG PG RGSPG +G +G
Sbjct: 934 PGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGP 993
Query: 511 XXXXXXXXXXXVQGESGRDGSPGLPGMRG 539
GE GRDG+PG G G
Sbjct: 994 PGPQGLPGQPGTAGEPGRDGNPGSDGQPG 1022
Score = 190 (71.9 bits), Expect = 5.3e-247, Sum P(5) = 5.3e-247
Identities = 42/106 (39%), Positives = 50/106 (47%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PGP G+ G+PG GE G +G PG G G PG
Sbjct: 380 GPPGPPGNNGSPGGKGEMGPAGIPGAPGLIG---ARGPPGPAGTNGIPGTRGPSGEPGKN 436
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G +G PG+ G GE G PG GP+GE+G G PG G NG+PG G
Sbjct: 437 GAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAG 482
Score = 189 (71.6 bits), Expect = 3.5e-283, Sum P(6) = 3.5e-283
Identities = 48/115 (41%), Positives = 50/115 (43%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGP---PGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAP 637
GFPG +G G PG NG G GP PG GP G
Sbjct: 872 GFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEK 931
Query: 638 GTPGFQGLPGSPGP---AGENGKPGEAGPRG---ENGGPGLPGSKGENGIPGERG 686
G PG QG PGSPGP AG G G AGP G G PG G KGE+G PG G
Sbjct: 932 GPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASG 986
Score = 188 (71.2 bits), Expect = 3.2e-227, Sum P(5) = 3.2e-227
Identities = 45/115 (39%), Positives = 54/115 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
GFPG KG G G+NGE+G +G PG +G G PG P
Sbjct: 257 GFPGMKGHRGFDGRNGEKGETGAPGLKGENG---LPGDNGAPGPMGPRGAPGERGRPGLP 313
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGE---------NGIPGERG 686
G G G+ G G +G+PG GP G G PG PG+KGE NG PG+RG
Sbjct: 314 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRG 368
Score = 185 (70.2 bits), Expect = 9.2e-283, Sum P(6) = 9.2e-283
Identities = 44/108 (40%), Positives = 50/108 (46%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G G PG GE G GPPG GP G+ APG
Sbjct: 542 GGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG---------APGKN 592
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERGAQ 688
G +G PG PG G GK GE GP+G G G G KG++G PG +G Q
Sbjct: 593 GERGGPGGPGLPGPAGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQ 640
Score = 185 (70.2 bits), Expect = 9.2e-283, Sum P(6) = 9.2e-283
Identities = 43/109 (39%), Positives = 49/109 (44%)
Query: 579 VMGFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPG 638
+ G PG +G G+PG GE+G G G G GK G
Sbjct: 723 LQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGG 782
Query: 639 TPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERGA 687
+PG LPG GP G G+ GE GP G G PG PG GE G GERGA
Sbjct: 783 SPG---LPGIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGA 828
Score = 185 (70.2 bits), Expect = 3.2e-229, Sum P(5) = 3.2e-229
Identities = 37/73 (50%), Positives = 43/73 (58%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG G PGLPG+ G R G G +G+ G PG G G PG+NG PG G RG PGE+G
Sbjct: 778 KGEGGSPGLPGIAGPRGG----PGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEKG 833
Query: 312 RAGLPGTAGARGN 324
G PG AG G+
Sbjct: 834 EGGPPGPAGPTGS 846
Score = 184 (69.8 bits), Expect = 1.2e-282, Sum P(6) = 1.2e-282
Identities = 45/117 (38%), Positives = 52/117 (44%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G G GKNGE G GPPG GPAG G P
Sbjct: 596 GGPGGPGLPGPAGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTG------GPP 649
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPG---------LPGSKGENGIPGERGAQ 688
G G PG PGP GE G PG G +G++G PG +PG++G G PG G +
Sbjct: 650 GENGKPGEPGPKGEVGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGK 706
Score = 184 (69.8 bits), Expect = 8.0e-268, Sum P(6) = 8.0e-268
Identities = 51/143 (35%), Positives = 55/143 (38%)
Query: 400 PGSAGMTGPPGLSGARGPPG---PAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXX 456
PG G G PG +G RGP G PAG NGIPG++GP GE G G G G GE
Sbjct: 469 PGEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGT 528
Query: 457 XXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXX 516
G PGS GE G PG GP+G
Sbjct: 529 PGGPGIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGA 588
Query: 517 XXXXXVQGESGRDGSPGLPGMRG 539
GE G G PGLPG G
Sbjct: 589 PGK---NGERGGPGGPGLPGPAG 608
Score = 184 (69.8 bits), Expect = 2.5e-237, Sum P(5) = 2.5e-237
Identities = 42/106 (39%), Positives = 48/106 (45%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G GP G GAPG G RG+ GP G +G G+ +PG
Sbjct: 1064 GETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAA 1123
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G QG GSPGPAG G G GP G++G G PG G G G RG
Sbjct: 1124 GHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRG 1169
Score = 183 (69.5 bits), Expect = 1.1e-266, Sum P(6) = 1.1e-266
Identities = 42/109 (38%), Positives = 50/109 (45%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PGP G G G+ G G+ G PG +G G PG
Sbjct: 509 GGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPGPS 568
Query: 641 GFQGLPGS---PGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G +G PG PGP G +G PG+ G RG GGPGLPG G+NG G +G
Sbjct: 569 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGETGPQG 617
Score = 182 (69.1 bits), Expect = 7.8e-258, Sum P(6) = 7.8e-258
Identities = 41/108 (37%), Positives = 45/108 (41%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG GS G G GE GS G PG G G APG
Sbjct: 1019 GQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPA 1078
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERGAQ 688
G +G PG GP G+ G+ GE G G G G PG+ G G PG G Q
Sbjct: 1079 GARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGHQ 1126
Score = 182 (69.1 bits), Expect = 5.4e-201, Sum P(4) = 5.4e-201
Identities = 48/140 (34%), Positives = 55/140 (39%)
Query: 400 PGSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXX 459
PG G GP G SG RG GPAG +G PG G G PG G +G+ G+ GER
Sbjct: 1048 PGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGH 1107
Query: 460 XXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXX 519
G GSPG G P RGP G +
Sbjct: 1108 RGFPGNPGPPGSPGAAGHQGAIGSPGPAG-P--RGPVGPHGPPGKDGTSGHPGPIGPPGP 1164
Query: 520 XXVQGESGRDGSPGLPGMRG 539
+GE G +GSPG PG G
Sbjct: 1165 RGNRGERGSEGSPGHPGQPG 1184
Score = 181 (68.8 bits), Expect = 1.4e-230, Sum P(5) = 1.4e-230
Identities = 41/80 (51%), Positives = 48/80 (60%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENG--SP----GPMGPRGQ 306
G SG PGL GM G R G G G KG+ G PG G +G+PG++G P GP GP GQ
Sbjct: 716 GASGSPGLQGMPGERGG-PGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPAGQ 774
Query: 307 PGERGRAG---LPGTAGARG 323
PG++G G LPG AG RG
Sbjct: 775 PGDKGEGGSPGLPGIAGPRG 794
Score = 180 (68.4 bits), Expect = 1.0e-279, Sum P(6) = 1.0e-279
Identities = 51/147 (34%), Positives = 59/147 (40%)
Query: 399 LPGSAGMTGPPGLSGARGPPGPAGTNG---IPGQRGPSGEPGKNGAKGEPGQRGERXXXX 455
+PG+ G +G PG +GA+G PG G G PG GP GE GK+G+ GEPG G
Sbjct: 423 IPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANG------ 476
Query: 456 XXXXXXXXXXXXXXXXXXXXXTNGIPGS---PGERGSPGFRGPAGSNXXXXXXXXXXXXX 512
NGIPG PGERG PG PAG
Sbjct: 477 ---LPGAAGERGPSGFRGPAGPNGIPGEKGPPGERGGPG---PAGPRGVAGEPGRDGTPG 530
Query: 513 XXXXXXXXXVQGESGRDGSPGLPGMRG 539
G G DG PG PG +G
Sbjct: 531 GPGIRGMPGSPGGPGNDGKPGPPGSQG 557
Score = 179 (68.1 bits), Expect = 3.9e-282, Sum P(6) = 3.9e-282
Identities = 43/112 (38%), Positives = 48/112 (42%)
Query: 581 GFPGPKGSEGAPGKNG------ERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXX 634
G PGP G GAPGK+G GS G PG GP G
Sbjct: 887 GNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPL 946
Query: 635 XAPGTPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G +GL G PG G G PG G +GE+G PG G GE G PG +G
Sbjct: 947 GIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQG 998
Score = 179 (68.1 bits), Expect = 3.9e-282, Sum P(6) = 3.9e-282
Identities = 45/112 (40%), Positives = 50/112 (44%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQG-PAGKXXXXXXXXXXXXX--XXXXXXXXXXAP 637
G GP G G G GERGS G PGT G P G+ P
Sbjct: 845 GSSGPAGPPGPQGVKGERGSPGGPGTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPP 904
Query: 638 GTPGFQGLPGSPG---PAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G G PG+PG P G+ G+PGE GP G G PG PG G G+ G RG
Sbjct: 905 GPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARG 956
Score = 178 (67.7 bits), Expect = 2.0e-249, Sum P(6) = 2.0e-249
Identities = 37/71 (52%), Positives = 44/71 (61%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G G+PG +G G G++GAKG+ GA G +GE G PG G G G G PGE G
Sbjct: 416 GPAGTNGIPGTRGP-SGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGA 474
Query: 313 AGLPGTAGARG 323
GLPG AG RG
Sbjct: 475 NGLPGAAGERG 485
Score = 178 (67.7 bits), Expect = 9.6e-246, Sum P(5) = 9.6e-246
Identities = 42/106 (39%), Positives = 46/106 (43%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G+ GA G +G RGS G PG GP G +PG+
Sbjct: 308 GRPGLPGAAGARGNDGARGSDGQPGPPGPPG------TAGFPGSPGAKGEVGPAGSPGSN 361
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G G PGP G G G GP G NG PG G G GIPG G
Sbjct: 362 GSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPG 407
Score = 177 (67.4 bits), Expect = 1.2e-247, Sum P(6) = 1.2e-247
Identities = 37/71 (52%), Positives = 40/71 (56%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
G G GLPG G R G G +G +G G+ GE G PGE G PGP GPRG GE GR
Sbjct: 470 GEPGANGLPGAAGER----GPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGR 525
Query: 313 AGLPGTAGARG 323
G PG G RG
Sbjct: 526 DGTPGGPGIRG 536
Score = 177 (67.4 bits), Expect = 1.4e-236, Sum P(5) = 1.4e-236
Identities = 42/115 (36%), Positives = 49/115 (42%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PGP G G GK+G+RG +GP G G G + G
Sbjct: 1046 GHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIK 1105
Query: 641 GFQGLPGSPGPAGENG---------KPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G +G PG+PGP G G PG AGPRG G G PG G +G PG G
Sbjct: 1106 GHRGFPGNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIG 1160
Score = 176 (67.0 bits), Expect = 6.6e-221, Sum P(5) = 6.6e-221
Identities = 48/147 (32%), Positives = 58/147 (39%)
Query: 399 LPGSAGMTGPPGLSGARGPPGPAGT---NGIPGQRGPSGE---PGKNGAKGEPGQRGERX 452
L G+ G+ GPPG+ G RG PGP G +G PG G +GE PG G G+PG GE
Sbjct: 951 LTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAGEPG 1010
Query: 453 XXXXXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXX 512
NG PG+PG G PG GP G +
Sbjct: 1011 RDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAG 1070
Query: 513 XXXXXXXXXVQGESGRDGSPGLPGMRG 539
G +G G+PG G RG
Sbjct: 1071 PSGA------PGPAGARGAPGPQGPRG 1091
Score = 175 (66.7 bits), Expect = 2.2e-236, Sum P(5) = 2.2e-236
Identities = 42/112 (37%), Positives = 45/112 (40%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGP------PGTQGPAGKXXXXXXXXXXXXXXXXXXXXXX 634
G PGP+G G G+ GERGS+G PG GP G
Sbjct: 1082 GAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGHQGAIGSPGPAGPRGPV 1141
Query: 635 XAPGTPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G PG G G PGP G G G G RG G PG PG G G PG G
Sbjct: 1142 GPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1193
Score = 174 (66.3 bits), Expect = 3.8e-266, Sum P(6) = 3.8e-266
Identities = 50/139 (35%), Positives = 55/139 (39%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G G TGP G G GPPGP G GIPG GP PG+NG GEPG +GE
Sbjct: 617 GPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGP---PGENGKPGEPGPKGE---------- 663
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXXX 520
G PG G+ G+PG RGP G+
Sbjct: 664 --------------VGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGKGPA 709
Query: 521 XVQGESGRDGSPGLPGMRG 539
G G GSPGL GM G
Sbjct: 710 GPPGPPGASGSPGLQGMPG 728
Score = 174 (66.3 bits), Expect = 3.8e-266, Sum P(6) = 3.8e-266
Identities = 46/144 (31%), Positives = 55/144 (38%)
Query: 399 LPGSAGMTGPPGLSGARGP---PGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXX 455
+PG+ G GPPG G +GP PGP G +G PG +G GE G G+ G G++GE
Sbjct: 690 IPGARGGAGPPGPEGGKGPAGPPGPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAG 749
Query: 456 XXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXX 515
G PG GE GSPG G AG
Sbjct: 750 ADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAG 809
Query: 516 XXXXXXVQGESGRDGSPGLPGMRG 539
GE G G G PG +G
Sbjct: 810 FPGAPGQNGEPGAKGERGAPGEKG 833
Score = 173 (66.0 bits), Expect = 4.9e-266, Sum P(6) = 4.9e-266
Identities = 46/143 (32%), Positives = 53/143 (37%)
Query: 400 PGSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXX 459
PGS G +G PG G GP G G G PG +G G PGKNG +G PG G
Sbjct: 553 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGE 612
Query: 460 XXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXX---XXXXXXXXXXXX 516
+G PG G +G PG GP G N
Sbjct: 613 TGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEVGAPGAPGG 672
Query: 517 XXXXXVQGESGRDGSPGLPGMRG 539
GE G G+ G+PG RG
Sbjct: 673 KGDSGAPGERGPPGTAGIPGARG 695
Score = 173 (66.0 bits), Expect = 6.7e-249, Sum P(6) = 6.7e-249
Identities = 34/73 (46%), Positives = 44/73 (60%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G+PG PG+ G R G G G +G PG +G +G PG+NG+ G G RG+ GE G
Sbjct: 398 GPAGIPGAPGLIGAR----GPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGS 453
Query: 313 AGLPGTAGARGND 325
G+PG G G D
Sbjct: 454 PGIPGPKGEDGKD 466
Score = 172 (65.6 bits), Expect = 2.3e-184, Sum P(4) = 2.3e-184
Identities = 42/88 (47%), Positives = 49/88 (55%)
Query: 253 GPSGMPGLPGMKGH--RKGFDGRDGAKGDSGAPGLKG---ENGLPGENGSPG------PM 301
GP G+PG PG G R G G DG G G+PG KG ENG PG G+PG P+
Sbjct: 995 GPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1054
Query: 302 GPRGQPGERGR------AGLPGTAGARG 323
GP G+ G+RG +G PG AGARG
Sbjct: 1055 GPSGKSGDRGETGPAGPSGAPGPAGARG 1082
Score = 171 (65.3 bits), Expect = 2.7e-281, Sum P(6) = 2.7e-281
Identities = 40/106 (37%), Positives = 44/106 (41%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG KG G+PG G G G PG +G G APG
Sbjct: 773 GQPGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEK 832
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
G G PG GP G +G G GP+G G G PG G G PG RG
Sbjct: 833 GEGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGPGTAGFPGGRG 878
Score = 171 (65.3 bits), Expect = 5.2e-247, Sum P(6) = 5.2e-247
Identities = 37/75 (49%), Positives = 45/75 (60%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
+G +G PG+PG KG DG+DG+ G+ GA GL G G G +G GP GP G PGE+G
Sbjct: 448 RGEAGSPGIPGPKGE----DGKDGSPGEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKG 503
Query: 312 ---RAGLPGTAGARG 323
G PG AG RG
Sbjct: 504 PPGERGGPGPAGPRG 518
Score = 171 (65.3 bits), Expect = 5.3e-245, Sum P(5) = 5.3e-245
Identities = 46/123 (37%), Positives = 52/123 (42%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G G KG GA G+ GE GS G PG +G GK G
Sbjct: 434 GKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAGERGPSGFRGPA 493
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRG---------ENGGPGL------PGSKGENGIPGER 685
G G+PG GP GE G PG AGPRG GGPG+ PG G +G PG
Sbjct: 494 GPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPP 553
Query: 686 GAQ 688
G+Q
Sbjct: 554 GSQ 556
Score = 171 (65.3 bits), Expect = 6.8e-209, Sum P(4) = 6.8e-209
Identities = 35/72 (48%), Positives = 43/72 (59%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G PG G+KG R G G G +G PG +G G PG NG+PGP GP G PG+ G
Sbjct: 848 GPAGPPGPQGVKGER----GSPGGPGTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGP 903
Query: 313 AGLPGTAGARGN 324
G G +G+ GN
Sbjct: 904 PGPAGNSGSPGN 915
Score = 170 (64.9 bits), Expect = 1.3e-269, Sum P(6) = 1.3e-269
Identities = 38/84 (45%), Positives = 42/84 (50%)
Query: 983 GKPGSNGSPGERGPPGAQGPPGISGTPGEPGRDGNAGSDGLPGRDGSSGPKGDRGENGSP 1042
G GS G G RGP G GPPG GT G PG G G G G GS G G G+ G P
Sbjct: 1127 GAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1186
Query: 1043 GLPGAPGHVGPPGNSGPAGKPGDR 1066
G PGAPG G + G G++
Sbjct: 1187 GPPGAPGPCCGGGAAAIVGVGGEK 1210
Score = 170 (64.9 bits), Expect = 1.0e-265, Sum P(6) = 1.0e-265
Identities = 45/139 (32%), Positives = 53/139 (38%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G G GP G GA G PG G +G PG+RGP G G GA+G G G
Sbjct: 653 GKPGEPGPKGEVGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGKGPAGPP 712
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXXX 520
G PGSPG +G G G AG++
Sbjct: 713 GPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPA 772
Query: 521 XVQGESGRDGSPGLPGMRG 539
G+ G GSPGLPG+ G
Sbjct: 773 GQPGDKGEGGSPGLPGIAG 791
Score = 170 (64.9 bits), Expect = 1.2e-227, Sum P(5) = 1.2e-227
Identities = 39/77 (50%), Positives = 44/77 (57%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPG------ENGSPGPMGPRGQ 306
GP+G PG PG +G GAKG+ GAPG KGE G PG +G GP GP+G
Sbjct: 806 GPAGFPGAPGQ-------NGEPGAKGERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGV 858
Query: 307 PGERGRAGLPGTAGARG 323
GERG G PGTAG G
Sbjct: 859 KGERGSPGGPGTAGFPG 875
Score = 169 (64.5 bits), Expect = 4.4e-281, Sum P(6) = 4.4e-281
Identities = 43/106 (40%), Positives = 46/106 (43%)
Query: 584 GPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTPGFQ 643
GP G G PG GE GS G PG GP G G PG +
Sbjct: 767 GPPGPAGQPGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPGQN---GEPGAK 823
Query: 644 GLPGSPGPAGENGKPGEAGPRGENGGPGLPGS---KGENGIPGERG 686
G G+PG GE G PG AGP G +G G PG KGE G PG G
Sbjct: 824 GERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGPG 869
Score = 169 (64.5 bits), Expect = 1.1e-208, Sum P(4) = 1.1e-208
Identities = 40/107 (37%), Positives = 43/107 (40%)
Query: 581 GFPGPKGSEGAPGKNGERGSSGPPGTQGPAGKXXXXXXXXXXXXXXXXXXXXXXXAPGTP 640
G PG G G PG G+ G GPPG+ G G P
Sbjct: 113 GPPGIPGRNGDPGLPGQPGLPGPPGSPGICESCPTGGQNYSPQFDSYDVKSGVGGMGGYP 172
Query: 641 GFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERGA 687
G G PG PGP G +G PG G G G PG PG G G PG GA
Sbjct: 173 GPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGA 219
Score = 168 (64.2 bits), Expect = 6.9e-259, Sum P(6) = 6.9e-259
Identities = 46/139 (33%), Positives = 52/139 (37%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G+ G+ G GL G G PGP G G PG+RG G PG GA+G G RG
Sbjct: 278 GAPGLKGENGLPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 337
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXXX 520
G GSPG GSPG RG G
Sbjct: 338 GTAGFPGSPGAKGEV---GPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGK 394
Query: 521 XVQGESGRDGSPGLPGMRG 539
G +G G+PGL G RG
Sbjct: 395 GEMGPAGIPGAPGLIGARG 413
Score = 167 (63.8 bits), Expect = 2.4e-278, Sum P(6) = 2.4e-278
Identities = 35/71 (49%), Positives = 38/71 (53%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP G PG PG GH G G G +G G PG G G PG G+ GP GP G+ GE GR
Sbjct: 176 GPPGPPGPPGSSGH-PGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGESGR 234
Query: 313 AGLPGTAGARG 323
G PG G G
Sbjct: 235 PGRPGERGLPG 245
Score = 167 (63.8 bits), Expect = 8.8e-259, Sum P(6) = 8.8e-259
Identities = 47/145 (32%), Positives = 54/145 (37%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G+ G G PGL GA G G G G GQ GP G PG G G PG +GE
Sbjct: 302 GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSN 361
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRG---PAG---SNXXXXXXXXXXXXXXX 514
G PG PG GSPG +G PAG +
Sbjct: 362 GSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPPGPAGTN 421
Query: 515 XXXXXXXVQGESGRDGSPGLPGMRG 539
GE G++G+ G PG RG
Sbjct: 422 GIPGTRGPSGEPGKNGAKGEPGARG 446
Score = 167 (63.8 bits), Expect = 8.7e-253, Sum P(6) = 8.7e-253
Identities = 49/146 (33%), Positives = 57/146 (39%)
Query: 400 PGSAGMTGPPGLSGARGPPG------PAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXX 453
PGS+G G PG G +GPPG PAG G PG GP+G GK+G G PG+ GER
Sbjct: 184 PGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGESGRPGRPGERGL 243
Query: 454 XXXXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXX 513
+G G GE G+PG +G G
Sbjct: 244 PGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENG---------LPGDNGA 294
Query: 514 XXXXXXXXVQGESGRDGSPGLPGMRG 539
GE GR G PG G RG
Sbjct: 295 PGPMGPRGAPGERGRPGLPGAAGARG 320
Score = 167 (63.8 bits), Expect = 1.7e-163, Sum P(3) = 1.7e-163
Identities = 35/72 (48%), Positives = 41/72 (56%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG +G G G+KGHR GF G G G GA G +G G PG G GP+GP G PG+ G
Sbjct: 1093 KGETGERGSNGIKGHR-GFPGNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDG 1151
Query: 312 RAGLPGTAGARG 323
+G PG G G
Sbjct: 1152 TSGHPGPIGPPG 1163
Score = 166 (63.5 bits), Expect = 5.2e-229, Sum P(5) = 5.2e-229
Identities = 35/72 (48%), Positives = 37/72 (51%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG G PG PG KG G G G G +G PG +G G PG G GP GP G PG G
Sbjct: 661 KGEVGAPGAPGGKGD-SGAPGERGPPGTAGIPGARGGAGPPGPEGGKGPAGPPGPPGASG 719
Query: 312 RAGLPGTAGARG 323
GL G G RG
Sbjct: 720 SPGLQGMPGERG 731
Score = 166 (63.5 bits), Expect = 2.3e-208, Sum P(4) = 2.3e-208
Identities = 39/77 (50%), Positives = 43/77 (55%)
Query: 253 GPSGMPGL---PGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQP 307
GPSG PG PG G+ G G G KGD+G PG KG G G GSPGP+G G
Sbjct: 893 GPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLT 952
Query: 308 GERGRAGLPGTAGARGN 324
G RG AG PG G RG+
Sbjct: 953 GARGLAGPPGMPGPRGS 969
Score = 166 (63.5 bits), Expect = 7.1e-202, Sum P(5) = 7.1e-202
Identities = 39/76 (51%), Positives = 42/76 (55%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPG---E 309
G G+ G PGM G R G G G KG+SG PG G NG E G PGP G GQPG E
Sbjct: 953 GARGLAGPPGMPGPR-GSPGPQGIKGESGKPGASGHNG---ERGPPGPQGLPGQPGTAGE 1008
Query: 310 RGRAGLPGTAGARGND 325
GR G PG+ G G D
Sbjct: 1009 PGRDGNPGSDGQPGRD 1024
Score = 166 (63.5 bits), Expect = 7.1e-202, Sum P(5) = 7.1e-202
Identities = 36/76 (47%), Positives = 44/76 (57%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPG---ENGSPGPMGPRGQPGE 309
GP G+ GL G +G G G G +G G G+KGE+G PG NG GP GP+G PG+
Sbjct: 944 GPLGIAGLTGARG-LAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQ 1002
Query: 310 RGRAGLPGTAGARGND 325
G AG PG G G+D
Sbjct: 1003 PGTAGEPGRDGNPGSD 1018
Score = 165 (63.1 bits), Expect = 2.2e-246, Sum P(6) = 2.2e-246
Identities = 34/74 (45%), Positives = 43/74 (58%)
Query: 253 GPSGMPGL---PGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGE 309
GP G PG+ PG KG+ G G++G +G G PGL G G GE G GP GP G G+
Sbjct: 569 GPRGQPGVMGFPGPKGN-DGAPGKNGERGGPGGPGLPGPAGKNGETGPQGPPGPTGPAGD 627
Query: 310 RGRAGLPGTAGARG 323
+G +G PG G +G
Sbjct: 628 KGDSGPPGPQGLQG 641
Score = 165 (63.1 bits), Expect = 2.2e-246, Sum P(6) = 2.2e-246
Identities = 36/75 (48%), Positives = 42/75 (56%)
Query: 252 KGPSGMPGLPGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGE 309
+G SG PG PG G R G G G KG+ GAPG GE G PG G PGP G G+ G
Sbjct: 556 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGETGP 615
Query: 310 RGRAGLPGTAGARGN 324
+G G G AG +G+
Sbjct: 616 QGPPGPTGPAGDKGD 630
Score = 165 (63.1 bits), Expect = 6.7e-229, Sum P(5) = 6.7e-229
Identities = 36/74 (48%), Positives = 41/74 (55%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENG---LPGENGSPGPMGPRGQPGE 309
G +G PG PG KG G G G KGDSGAPG +G G +PG G GP GP G G
Sbjct: 650 GENGKPGEPGPKGE-VGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGKGP 708
Query: 310 RGRAGLPGTAGARG 323
G G PG +G+ G
Sbjct: 709 AGPPGPPGASGSPG 722
Score = 164 (62.8 bits), Expect = 5.0e-278, Sum P(6) = 5.0e-278
Identities = 35/75 (46%), Positives = 39/75 (52%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMG---PRGQPG 308
+G G PG PG G GF G GAKG+ G G G NG PG+ G PGP G +G PG
Sbjct: 325 RGSDGQPGPPGPPG-TAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPG 383
Query: 309 ERGRAGLPGTAGARG 323
G G PG G G
Sbjct: 384 PPGNNGSPGGKGEMG 398
Score = 164 (62.8 bits), Expect = 1.8e-252, Sum P(6) = 1.8e-252
Identities = 51/143 (35%), Positives = 57/143 (39%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G GM G PG +G GPPGP G++G PG P G PG G GEPGQ G
Sbjct: 164 GVGGMGGYPGPAGPPGPPGPPGSSGHPGS--P-GSPGYQGPPGEPGQAGP------AGPP 214
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERG---SPGFRGPAGSNXXXXXXXXXXXXXXXXXX 517
+G PG PGERG PG +GPAG
Sbjct: 215 GPPGALGPAGPAGKDGESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGR---- 270
Query: 518 XXXXVQGESGRDGSPGLPGMRGL 540
GE G G+PGL G GL
Sbjct: 271 -----NGEKGETGAPGLKGENGL 288
Score = 164 (62.8 bits), Expect = 5.9e-248, Sum P(6) = 5.9e-248
Identities = 37/76 (48%), Positives = 39/76 (51%)
Query: 251 HKGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGE---NGSPGPMGPRGQP 307
H G G PG PG G G G G G GAPGL G G PG NG PG GP G+P
Sbjct: 375 HAGAQGPPGPPGNNGSPGG-KGEMGPAGIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEP 433
Query: 308 GERGRAGLPGTAGARG 323
G+ G G PG G RG
Sbjct: 434 GKNGAKGEPGARGERG 449
Score = 163 (62.4 bits), Expect = 2.3e-258, Sum P(6) = 2.3e-258
Identities = 45/144 (31%), Positives = 54/144 (37%)
Query: 399 LPGSAGMTGPPGLSGARG---PPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXX 455
+ G AGM G PG+ G RG G G G PG +G +G PG NGA PG G R
Sbjct: 249 IKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGDNGA---PGPMGPRGAPG 305
Query: 456 XXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXX 515
++G PG PG G+ GF G G+
Sbjct: 306 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPG 365
Query: 516 XXXXXXVQGESGRDGSPGLPGMRG 539
QG +G G PG PG G
Sbjct: 366 QRGEPGPQGHAGAQGPPGPPGNNG 389
Score = 163 (62.4 bits), Expect = 3.6e-246, Sum P(6) = 3.6e-246
Identities = 33/72 (45%), Positives = 41/72 (56%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G G G +G G G G KGDSG PG +G G+PG G PG G G+PG +G
Sbjct: 605 GPAGKNGETGPQGP-PGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGE 663
Query: 313 AGLPGTAGARGN 324
G PG G +G+
Sbjct: 664 VGAPGAPGGKGD 675
Score = 163 (62.4 bits), Expect = 1.0e-179, Sum P(4) = 1.0e-179
Identities = 35/74 (47%), Positives = 40/74 (54%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPG---E 309
GP+G G PG G R G G G +GD G G +G NG+ G G PG GP G PG
Sbjct: 1067 GPAGPSGAPGPAGAR-GAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGH 1125
Query: 310 RGRAGLPGTAGARG 323
+G G PG AG RG
Sbjct: 1126 QGAIGSPGPAGPRG 1139
Score = 162 (62.1 bits), Expect = 4.6e-246, Sum P(6) = 4.6e-246
Identities = 35/72 (48%), Positives = 39/72 (54%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KGP G G PG G R G G G G G PG++G G PG G+ G GP G GE G
Sbjct: 502 KGPPGERGGPGPAGPR-GVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPPGSQGESG 560
Query: 312 RAGLPGTAGARG 323
R G PG +G RG
Sbjct: 561 RPGPPGPSGPRG 572
Score = 162 (62.1 bits), Expect = 1.4e-228, Sum P(5) = 1.4e-228
Identities = 36/81 (44%), Positives = 46/81 (56%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENG------LPGENG---SPGPMG 302
+GP G G+PG +G G G +G KG +G PG G +G +PGE G SPGP G
Sbjct: 682 RGPPGTAGIPGARGGA-GPPGPEGGKGPAGPPGPPGASGSPGLQGMPGERGGPGSPGPKG 740
Query: 303 PRGQPGERGRAGLPGTAGARG 323
+G+PG G G+PG G RG
Sbjct: 741 EKGEPGGAGADGVPGKDGPRG 761
Score = 162 (62.1 bits), Expect = 2.8e-222, Sum P(5) = 2.8e-222
Identities = 44/139 (31%), Positives = 54/139 (38%)
Query: 401 GSAGMTGPPGLSGARGPPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRGERXXXXXXXXX 460
G G GPPG G G PGP G G+ G RG +G PG G +G PG +G +
Sbjct: 926 GQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGAS 985
Query: 461 XXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXXXXXXXXX 520
G+PG PG G PG G GS+
Sbjct: 986 GHNGERGPPG------PQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGD------- 1032
Query: 521 XVQGESGRDGSPGLPGMRG 539
+GE+G G+PG PG G
Sbjct: 1033 --RGENGSPGAPGAPGHPG 1049
Score = 158 (60.7 bits), Expect = 1.2e-245, Sum P(6) = 1.2e-245
Identities = 35/72 (48%), Positives = 38/72 (52%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
+GPSG PG G KG G G G G G PG KGE+G G G PG G G GERG
Sbjct: 427 RGPSGEPGKNGAKGE-PGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAGERG 485
Query: 312 RAGLPGTAGARG 323
+G G AG G
Sbjct: 486 PSGFRGPAGPNG 497
Score = 158 (60.7 bits), Expect = 3.6e-228, Sum P(5) = 3.6e-228
Identities = 39/77 (50%), Positives = 43/77 (55%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGA---PGLKGENGLPGENGSPG-P--MGPRGQ 306
GP G G PG G G G+DG +G +G PG G+ G GE GSPG P GPRG
Sbjct: 737 GPKGEKGEPGGAG-ADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGGSPGLPGIAGPRGG 795
Query: 307 PGERGRAGLPGTAGARG 323
PGERG G PG AG G
Sbjct: 796 PGERGEHGPPGPAGFPG 812
Score = 158 (60.7 bits), Expect = 7.0e-183, Sum P(4) = 7.0e-183
Identities = 34/74 (45%), Positives = 37/74 (50%)
Query: 253 GPSGMPGLPGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGER 310
G G G PG KG R G G GA G G PG G +G G+ G GP GP G PG
Sbjct: 1019 GQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPA 1078
Query: 311 GRAGLPGTAGARGN 324
G G PG G RG+
Sbjct: 1079 GARGAPGPQGPRGD 1092
Score = 157 (60.3 bits), Expect = 8.9e-183, Sum P(4) = 8.9e-183
Identities = 33/77 (42%), Positives = 40/77 (51%)
Query: 252 KGPSGMPGLPGMKGHRK-----GFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQ 306
+G +G PG PG GH G G+ G +G++G G G G G G+PGP GPRG
Sbjct: 1033 RGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGD 1092
Query: 307 PGERGRAGLPGTAGARG 323
GE G G G G RG
Sbjct: 1093 KGETGERGSNGIKGHRG 1109
Score = 156 (60.0 bits), Expect = 3.5e-277, Sum P(6) = 3.5e-277
Identities = 35/73 (47%), Positives = 41/73 (56%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG +G PGL G G G +G G G GAPG +G GLPG G+ G G RG G+ G
Sbjct: 274 KGETGAPGLKGENG-LPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG 332
Query: 312 RAGLPGTAGARGN 324
G PGTAG G+
Sbjct: 333 PPGPPGTAGFPGS 345
Score = 156 (60.0 bits), Expect = 2.6e-207, Sum P(4) = 2.6e-207
Identities = 33/71 (46%), Positives = 38/71 (53%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
G G+PG PG G+ G G GA G G PG G +G PG G GP G GQPGE+G
Sbjct: 875 GGRGLPGPPGNNGN-PGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGP 933
Query: 313 AGLPGTAGARG 323
G G G+ G
Sbjct: 934 PGAQGPPGSPG 944
Score = 155 (59.6 bits), Expect = 2.5e-245, Sum P(6) = 2.5e-245
Identities = 35/73 (47%), Positives = 40/73 (54%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
G G PG PG++G G G G G G PG +GE+G PG PGP GPRGQPG G
Sbjct: 524 GRDGTPGGPGIRG-MPGSPGGPGNDGKPGPPGSQGESGRPGP---PGPSGPRGQPGVMGF 579
Query: 313 AGLPGTAGARGND 325
G G GA G +
Sbjct: 580 PGPKGNDGAPGKN 592
Score = 154 (59.3 bits), Expect = 8.8e-259, Sum P(6) = 8.8e-259
Identities = 33/71 (46%), Positives = 38/71 (53%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP G G G G G +G G KG+ G G+ G GL G G PGP G G PG RG
Sbjct: 371 GPQGHAGAQGPPGP-PGNNGSPGGKGEMGPAGIPGAPGLIGARGPPGPAGTNGIPGTRGP 429
Query: 313 AGLPGTAGARG 323
+G PG GA+G
Sbjct: 430 SGEPGKNGAKG 440
Score = 154 (59.3 bits), Expect = 2.0e-251, Sum P(6) = 2.0e-251
Identities = 45/146 (30%), Positives = 50/146 (34%)
Query: 400 PGSAGMTGPPGLSGARGPPGPAGTNGI------PGQRGPSGEPGKNGAKGEPGQRGERXX 453
PG AG GPPG G+ G PG G+ G PGQ GP+G PG GA G G G+
Sbjct: 172 PGPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGE 231
Query: 454 XXXXXXXXXXXXXXXXXXXXXXXTNGIPGSPGERGSPGFRGPAGSNXXXXXXXXXXXXXX 513
G PG G RG G G G
Sbjct: 232 SGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGD 291
Query: 514 XXXXXXXXVQGESGRDGSPGLPGMRG 539
+G G G PGLPG G
Sbjct: 292 NGAPGPMGPRGAPGERGRPGLPGAAG 317
Score = 152 (58.6 bits), Expect = 1.4e-258, Sum P(6) = 1.4e-258
Identities = 34/71 (47%), Positives = 35/71 (49%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G PG G G R G G G G G PG G NG PG G GP G G PG G
Sbjct: 353 GPAGSPGSNGSPGQR-GEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGA 411
Query: 313 AGLPGTAGARG 323
G PG AG G
Sbjct: 412 RGPPGPAGTNG 422
Score = 152 (58.6 bits), Expect = 5.2e-245, Sum P(6) = 5.2e-245
Identities = 36/72 (50%), Positives = 39/72 (54%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG SG PG G++G G G G G G PG KGE G PG +PG G G PGERG
Sbjct: 628 KGDSGPPGPQGLQGI-PGTGGPPGENGKPGEPGPKGEVGAPG---APGGKGDSGAPGERG 683
Query: 312 RAGLPGTAGARG 323
G G GARG
Sbjct: 684 PPGTAGIPGARG 695
Score = 151 (58.2 bits), Expect = 2.0e-227, Sum P(5) = 2.0e-227
Identities = 33/72 (45%), Positives = 37/72 (51%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
+GP+G G PG G G G G G PG+ G G PGE G GP GP G PG G
Sbjct: 760 RGPAGPIGPPGPAGQ----PGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPG 815
Query: 312 RAGLPGTAGARG 323
+ G PG G RG
Sbjct: 816 QNGEPGAKGERG 827
Score = 151 (58.2 bits), Expect = 2.7e-200, Sum P(5) = 2.7e-200
Identities = 32/74 (43%), Positives = 41/74 (55%)
Query: 253 GPSGMPGLPGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGER 310
GP GMPG G G + KG G+ GA G +G G G GLPG+ G+ G G G PG
Sbjct: 959 GPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSD 1018
Query: 311 GRAGLPGTAGARGN 324
G+ G G+ G +G+
Sbjct: 1019 GQPGRDGSPGGKGD 1032
Score = 150 (57.9 bits), Expect = 1.5e-276, Sum P(6) = 1.5e-276
Identities = 34/71 (47%), Positives = 39/71 (54%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP+G PG PG G G G+DG +SG PG GE GLPG G GP G G PG +G
Sbjct: 209 GPAGPPGPPGALGPA-GPAGKDG---ESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGH 264
Query: 313 AGLPGTAGARG 323
G G G +G
Sbjct: 265 RGFDGRNGEKG 275
Score = 150 (57.9 bits), Expect = 1.5e-276, Sum P(6) = 1.5e-276
Identities = 37/84 (44%), Positives = 43/84 (51%)
Query: 253 GPSGMPGLPGMKGHR-----KGFDGRDGAKGDSG------APGLKGENGLPGENGSPGPM 301
G G PGLPG G R +G DG+ G G G +PG KGE G G GS G
Sbjct: 305 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSP 364
Query: 302 GPRGQPGERGRAGLPGTAGARGND 325
G RG+PG +G AG G G GN+
Sbjct: 365 GQRGEPGPQGHAGAQGPPGPPGNN 388
Score = 150 (57.9 bits), Expect = 7.0e-185, Sum P(4) = 7.0e-185
Identities = 33/73 (45%), Positives = 38/73 (52%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
GP G PG G+KG G G G G+ G PG +G G PG G PG G G G+ GR
Sbjct: 965 GPRGSPGPQGIKGE-SGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGR 1023
Query: 313 AGLPGTAGARGND 325
G PG G RG +
Sbjct: 1024 DGSPGGKGDRGEN 1036
Score = 149 (57.5 bits), Expect = 8.9e-185, Sum P(4) = 8.9e-185
Identities = 33/73 (45%), Positives = 37/73 (50%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
KG SG PG G G R G G G G G G G +G PG +G PG G G G+RG
Sbjct: 976 KGESGKPGASGHNGER-GPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRG 1034
Query: 312 RAGLPGTAGARGN 324
G PG GA G+
Sbjct: 1035 ENGSPGAPGAPGH 1047
Score = 147 (56.8 bits), Expect = 1.7e-244, Sum P(6) = 1.7e-244
Identities = 33/73 (45%), Positives = 36/73 (49%)
Query: 253 GPSGMPGLPGMKGH--RKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGER 310
G GMPG PG G+ + G G G G G PG G G PG G PGP G G PG+
Sbjct: 533 GIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 592
Query: 311 GRAGLPGTAGARG 323
G G PG G G
Sbjct: 593 GERGGPGGPGLPG 605
Score = 145 (56.1 bits), Expect = 3.6e-161, Sum P(3) = 3.6e-161
Identities = 33/73 (45%), Positives = 37/73 (50%)
Query: 253 GPSGMPGLPGMKGHRK--GFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGER 310
G G PG PG GH+ G G G +G G G G++G G G GP GPRG GER
Sbjct: 1112 GNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGER 1171
Query: 311 GRAGLPGTAGARG 323
G G PG G G
Sbjct: 1172 GSEGSPGHPGQPG 1184
Score = 141 (54.7 bits), Expect = 1.3e-275, Sum P(6) = 1.3e-275
Identities = 32/71 (45%), Positives = 36/71 (50%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
G SG PG PG +G G G KG +G PG G G G +G G G G PG +G
Sbjct: 230 GESGRPGRPG----ERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 285
Query: 313 AGLPGTAGARG 323
GLPG GA G
Sbjct: 286 NGLPGDNGAPG 296
Score = 140 (54.3 bits), Expect = 1.7e-275, Sum P(6) = 1.7e-275
Identities = 28/55 (50%), Positives = 31/55 (56%)
Query: 269 GFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGRAGLPGTAGARG 323
G G G G G PG G +G PG GSPG GP G+PG+ G AG PG GA G
Sbjct: 167 GMGGYPGPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALG 221
Score = 139 (54.0 bits), Expect = 1.6e-205, Sum P(4) = 1.6e-205
Identities = 32/74 (43%), Positives = 40/74 (54%)
Query: 252 KGPSGMPGLPGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGE 309
KG +G PG G G + G G G G +GA GL G G+PG GSPGP G +G+ G+
Sbjct: 922 KGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGK 981
Query: 310 RGRAGLPGTAGARG 323
G +G G G G
Sbjct: 982 PGASGHNGERGPPG 995
Score = 139 (54.0 bits), Expect = 1.6e-205, Sum P(4) = 1.6e-205
Identities = 34/80 (42%), Positives = 42/80 (52%)
Query: 251 HKGPSGMPGLPGMKGH--RKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMG---PRG 305
+ G G PG+ G KG + G G GA+G G+PG G GL G G GP G PRG
Sbjct: 909 NSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRG 968
Query: 306 QPGERGRAGLPGTAGARGND 325
PG +G G G GA G++
Sbjct: 969 SPGPQGIKGESGKPGASGHN 988
Score = 138 (53.6 bits), Expect = 2.7e-275, Sum P(6) = 2.7e-275
Identities = 34/80 (42%), Positives = 42/80 (52%)
Query: 252 KGPSGMPG---LPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQ-- 306
KG +G+PG PG G R G G G G GA G +G +G G +G PGP GP G
Sbjct: 283 KGENGLPGDNGAPGPMGPR-GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG 341
Query: 307 -PGERGRAGLPGTAGARGND 325
PG G G G AG+ G++
Sbjct: 342 FPGSPGAKGEVGPAGSPGSN 361
Score = 137 (53.3 bits), Expect = 2.0e-243, Sum P(6) = 2.0e-243
Identities = 35/81 (43%), Positives = 44/81 (54%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKG---ENGLPGENGSPGPMGPRGQ-- 306
+G G+ G PG KG+ G G++G +G G PGL G +NG G G PGP GP G
Sbjct: 571 RGQPGVMGFPGPKGN-DGAPGKNGERGGPGGPGLPGPAGKNGETGPQGPPGPTGPAGDKG 629
Query: 307 ----PGERGRAGLPGTAGARG------ 323
PG +G G+PGT G G
Sbjct: 630 DSGPPGPQGLQGIPGTGGPPGENGKPG 656
Score = 137 (53.3 bits), Expect = 4.1e-223, Sum P(5) = 4.1e-223
Identities = 35/80 (43%), Positives = 41/80 (51%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPG---LKGENGLPGENGS---PGPMGPRG 305
KG G PG G +G G G G+ G +G PG +KGE G PG G+ PG G G
Sbjct: 823 KGERGAPGEKG-EGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGPGTAGFPGGRGLPG 881
Query: 306 QPGERGRAGLPGTAGARGND 325
PG G G PG +GA G D
Sbjct: 882 PPGNNGNPGPPGPSGAPGKD 901
Score = 136 (52.9 bits), Expect = 4.4e-275, Sum P(6) = 4.4e-275
Identities = 33/73 (45%), Positives = 35/73 (47%)
Query: 253 GPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERGR 312
G G PG PG G G G GA G +G G GE+G PG G G GP G G G
Sbjct: 197 GYQGPPGEPGQAGPA-GPPGPPGALGPAGPAGKDGESGRPGRPGERGLPGPPGIKGPAGM 255
Query: 313 AGLPGTAGARGND 325
G PG G RG D
Sbjct: 256 PGFPGMKGHRGFD 268
Score = 134 (52.2 bits), Expect = 4.0e-243, Sum P(6) = 4.0e-243
Identities = 30/72 (41%), Positives = 37/72 (51%)
Query: 252 KGPSGMPGLPGMKGHRKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGERG 311
+GP+G G+PG KG G G G +G G+ GE G G G PG G G PG G
Sbjct: 490 RGPAGPNGIPGEKGP----PGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPG 545
Query: 312 RAGLPGTAGARG 323
G PG G++G
Sbjct: 546 NDGKPGPPGSQG 557
Score = 134 (52.2 bits), Expect = 6.2e-180, Sum P(4) = 6.2e-180
Identities = 33/73 (45%), Positives = 37/73 (50%)
Query: 253 GPSGMPGLPGMKGHR--KGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPGER 310
GPSG G G G G G GA+G G G +G+ G GE GS G G RG PG
Sbjct: 1055 GPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNP 1114
Query: 311 GRAGLPGTAGARG 323
G G PG AG +G
Sbjct: 1115 GPPGSPGAAGHQG 1127
Score = 124 (48.7 bits), Expect = 6.0e-159, Sum P(3) = 6.0e-159
Identities = 30/69 (43%), Positives = 33/69 (47%)
Query: 251 HKGPSGMPGLPGMKGH--RKGFDGRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPG 308
H+G G PG G +G G G+DG G G G G G GE GS G G GQPG
Sbjct: 1125 HQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1184
Query: 309 ERGRAGLPG 317
G G PG
Sbjct: 1185 PPGPPGAPG 1193
Score = 115 (45.5 bits), Expect = 5.4e-203, Sum P(4) = 5.4e-203
Identities = 25/50 (50%), Positives = 25/50 (50%)
Query: 637 PGTPGFQGLPGSPGPAGENGKPGEAGPRGENGGPGLPGSKGENGIPGERG 686
P TP LP GP G G PG G G NG PGLPG G G PG G
Sbjct: 92 PSTPA-PVLPDGHGPQGPKGDPGPPGIPGRNGDPGLPGQPGLPGPPGSPG 140
Score = 113 (44.8 bits), Expect = 8.6e-158, Sum P(3) = 8.6e-158
Identities = 23/42 (54%), Positives = 23/42 (54%)
Query: 1023 LPGRDGSSGPKGDRGENGSPGLPGAPGHVGPPGNSGPAGKPG 1064
LP G GPKGD G G PG G PG G PG GP G PG
Sbjct: 99 LPDGHGPQGPKGDPGPPGIPGRNGDPGLPGQPGLPGPPGSPG 140
Score = 110 (43.8 bits), Expect = 2.4e-272, Sum P(6) = 2.4e-272
Identities = 21/37 (56%), Positives = 22/37 (59%)
Query: 272 GRDGAKGDSGAPGLKGENGLPGENGSPGPMGPRGQPG 308
G G KGD G PG+ G NG PG G PG GP G PG
Sbjct: 104 GPQGPKGDPGPPGIPGRNGDPGLPGQPGLPGPPGSPG 140
Score = 109 (43.4 bits), Expect = 2.6e-193, Sum P(4) = 2.6e-193
Identities = 24/55 (43%), Positives = 25/55 (45%)
Query: 401 GSAGMTGPPGLSGARG------PPGPAGTNGIPGQRGPSGEPGKNGAKGEPGQRG 449
G G GPPG G G PPGP G G G G G PG+ G G PG G
Sbjct: 1139 GPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1193
|
