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Gene Model: Pgm2

NomenclatureGenomic Location
SymbolPgm2Chromosome1
NamePhosphoglucomutase-2Linkage mapunknown
SpeciesDracomimus familiarisGenome Coordinates1: 75 Mbp

Molecular Function

Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity.

Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.

2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.

Molecular Function Terms:

binding
   ion binding
      cation binding
         metal ion binding

catalytic activity
   isomerase activity
      intramolecular transferase activity
         intramolecular transferase activity, phosphotransferases
            phosphoglucomutase activity

Human Disease Association

No disease association.

Predicted Transcript
     1 CCCACCCACCCTCCTGGCCCAGCCCTCCAGCCCAGCCCAACCCTCCTGGCCAGGCCCGGC
    61 AAATGGCCCCATGGCAAAAAAAATCCTAAAACCTCAGAAATTGTCAAGCAGCTTGTTGCA
   121 AATGGAAAGACAGAAGAGCTCCAAAAATGTTTTGGTTCACGGATGGAATTTGGAACCGCA
   181 GGACTCCGAGCAGCCATGGGAGTAGGAACATCTCAGATGAATGATTTGACTATTATTCAG
   241 ACCACTCAGGGATTTTGTAGGTATCTTGAAAAGAGTTTCAGTGACCTAAAGAAAAGGGGA
   301 GTAGTAATTAGCTATGATGCTCGGGCTCATCCTTCAAGTGGAGGCAGCAGCAAAAGATTT
   361 GCAAGACTTGCTGCAACAACATTCATCAGTCAAGGTGTTCCTGTATACCTTTTTTCTGGT
   421 ATAACGCCAACTCCTTTCGTGCCCTATACAGTGACCCATCTGAAGCTTTGTGCTGGAATT
   481 ATGGTTACTGCATCTCATAATCCCAAGCAGGATAATGGATACAAGGTTTATTGGGACAAT
   541 GGTTCTCAGATCATTGCTCCTCATGATAAAGGAATTGCACAAGCTATTGAAGAAAACCTA
   601 GAGCCCTGGCCTCAAGCCTGGGATGACAGCCTGATTGATAAGAGTTCCCTTCTCCATGAT
   661 CCGTATGCATCTATTAACAAGGACTACTTCAAAGACATACAGAAACACTGCTTTCACAGG
   721 AACATAAACAAGGAGACAAAGCTGAAATTTGTCCATACCTCTGTGCATGGTGTAGGCCAT
   781 GAATTTGTGCAGTCAGCCTTTAAGGCATTTGACTTTATCCCTCCATTTGCTGTTCCTGAG
   841 CAGAAAGATCCTGATCCAGAATTTCCAACAGTAAAATACCCAAATCCTGAGGAGGGTAAA
   901 GGCGTACTGACACTGTCCTTTGCTTTAGCCAAAAAAGAAGGAGCTCAGATCATTTTAGCC
   961 AATGACCCTGATGCTGATCGGCTTGCTGTTGCAGAGAAACAAGAAGGTGGTGAATGGAAA
  1021 GTTTTTTCTGGCAATGAATCGGGAGCTCTTTTAGGCTGGTGGCTCTTCACTTGCTGGAAA
  1081 AATCAGAATCGGAATCCTGGTGCCGTCAAAGACATATACATGCTATCTAGCACTGTGTCC
  1141 TCCAAAATACTACGAGCTATCGCACTTAAAGAAGGCTTTCACTTTGAGGAAACATTAACA
  1201 GGATTCAAGTGGATGGGAAATCGAGCAAAGCAGCTCCTAGACCAAGGAAAAACTGTCTTA
  1261 TTTGCTTTTGAAGAAGCTATTGGGTATATGTGCAGCCCTGTAGTTTTGGATAAAGATGGT
  1321 GTCAGTGCTGCAGTCATAACTGCAGAGATGGCCAGTTTTCTGGCAGCAAAGAATATATCA
  1381 TTGTCTCAGCAACTGAAGAACATTTACAATGAGTATGGCTTTCATGTTACCAAAGCTTCA
  1441 TATTTTATCTGTCACGATCAGAAGATCATTAAGGAACTGTTTGAGAAGCTTAGAAACTGT
  1501 GATGGAAAGAGCACATACCCAAAGACCTGTGGGAGATTTTCAGTGTCTGGAGTCAGGGAT
  1561 CTCACTACTGGGTATGACAGTAACCAGCCTGATAAAAAAGCTGTTCTCCCTTCAAGTAAG
  1621 AGTAGCCAGATGATAACATTCACTTTCAATAATGGATGTGTGGCAACTATGCGGACAAGC
  1681 GGGACTGAACCTAAAATCAAATACTATGCAGAGCTTTGTGCACCTCCTGGGAACAGTGAC
  1741 TTTGAAAAATTGAAGAAAGAACTGGATGAATTGGTTGATGCTATTGAAAAATATTTCTTT
  1801 GAGCCAGAAAAGAATAAACTGCAGTCCAAGCCAGAGTAA

Predicted Protein Product
PTHPPGPALQPSPTLLARPGKWPHGKKNPKTSEIVKQLVANGKTEELQKCFGSRMEFGTA
GLRAAMGVGTSQMNDLTIIQTTQGFCRYLEKSFSDLKKRGVVISYDARAHPSSGGSSKRF
ARLAATTFISQGVPVYLFSGITPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWDN
GSQIIAPHDKGIAQAIEENLEPWPQAWDDSLIDKSSLLHDPYASINKDYFKDIQKHCFHR
NINKETKLKFVHTSVHGVGHEFVQSAFKAFDFIPPFAVPEQKDPDPEFPTVKYPNPEEGK
GVLTLSFALAKKEGAQIILANDPDADRLAVAEKQEGGEWKVFSGNESGALLGWWLFTCWK
NQNRNPGAVKDIYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLLDQGKTVL
FAFEEAIGYMCSPVVLDKDGVSAAVITAEMASFLAAKNISLSQQLKNIYNEYGFHVTKAS
YFICHDQKIIKELFEKLRNCDGKSTYPKTCGRFSVSGVRDLTTGYDSNQPDKKAVLPSSK
SSQMITFTFNNGCVATMRTSGTEPKIKYYAELCAPPGNSDFEKLKKELDELVDAIEKYFF
EPEKNKLQSKPE
Protein Alignment to Mouse
sp|Q7TSV4|PGM2_MOUSE Phosphoglucomutase-2 OS=Mus musculus GN=Pgm2 PE=1 SV=1
      MGI:97564 Pgm1 phosphoglucomutase 1 (Chr 5)
        Length = 620

 Score = 2555 (904.5 bits), Expect = 2.7e-266, P = 2.7e-266
 Identities = 480/615 (78%), Positives = 533/615 (86%)

Query:     1 PTHPPGP---ALQPSPTLLARPGKWPHGKKNPKTSEIVKQLVANGKTEELQKCFGSRMEF 57
             PT  P P    L     L     +W    +NP TSE VKQL+A G  EEL+KCFG+RMEF
Sbjct:     6 PTETPAPEGSGLGMDARLDQETAQWLRWDQNPLTSESVKQLIAGGNKEELRKCFGARMEF 65

Query:    58 GTAGLRAAMGVGTSQMNDLTIIQTTQGFCRYLEKSFSDLKKRGVVISYDARAHPSSGGSS 117
             GTAGLRA MG G S+MNDLTIIQTTQGFCRYLEK FSDLK+RGVVIS+DARAHP+SGGSS
Sbjct:    66 GTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDARAHPASGGSS 125

Query:   118 KRFARLAATTFISQGVPVYLFSGITPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVY 177
             +RFARLAAT FI+QGVPVYLFS ITPTPFVPYTV+HLKLCAGIM+TASHNPKQDNGYKVY
Sbjct:   126 RRFARLAATAFITQGVPVYLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVY 185

Query:   178 WDNGSQIIAPHDKGIAQAIEENLEPWPQAWDDSLIDKSSLLHDPYASINKDYFKDIQKHC 237
             WDNG+QII+PHD+GI+QAIEENLEPWPQAW++SL+D S LLH+P ASI  DYF+D++K+C
Sbjct:   186 WDNGAQIISPHDRGISQAIEENLEPWPQAWEESLVDSSPLLHNPSASIGNDYFEDLKKYC 245

Query:   238 FHRNINKETKLKFVHTSVHGVGHEFVQSAFKAFDFIPPFAVPEQKDPDPEFPTVKYPNPE 297
             FHR +NKE+K+KFVHTSVHGVGHEFVQ AFKAFD  PP AVP+QKDPDPEFPTVKYPNPE
Sbjct:   246 FHRTVNKESKVKFVHTSVHGVGHEFVQLAFKAFDLAPPEAVPQQKDPDPEFPTVKYPNPE 305

Query:   298 EGKGVLTLSFALAKKEGAQIILANDPDADRLAVAEKQEGGEWKVFSGNESGALLGWWLFT 357
             EGKGVLTLSFALA K  A+I+LANDPDADRLAVAEKQ+ GEW+VFSGNE GALLGWWLFT
Sbjct:   306 EGKGVLTLSFALADKIKAKIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFT 365

Query:   358 CWKNQNRNPGAVKDIYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLLDQGK 417
              WK +N++   +KD YMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRA+QL DQGK
Sbjct:   366 SWKEKNQDQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAQQLGDQGK 425

Query:   418 TVLFAFEEAIGYMCSPVVLDKDGVSAAVITAEMASFLAAKNISLSQQLKNIYNEYGFHVT 477
             TVLFAFEEAIGYMC P VLDKDGVSAAVI AE+ASFLA KN+SLSQQL  IY EYG+H+T
Sbjct:   426 TVLFAFEEAIGYMCCPFVLDKDGVSAAVICAELASFLATKNLSLSQQLNAIYVEYGYHIT 485

Query:   478 KASYFICHDQKIIKELFEKLRNCDGKSTYPKTCGRFSVSGVRDLTTGYDSNQPDKKAVLP 537
              ASYFICHDQ  I+ LF  LRN DGK+ YPK CG+F +S +RDLTTGYD +QPDKKAVLP
Sbjct:   486 TASYFICHDQGTIQNLFGNLRNYDGKNNYPKMCGKFEISAIRDLTTGYDDSQPDKKAVLP 545

Query:   538 SSKSSQMITFTFNNGCVATMRTSGTEPKIKYYAELCAPPGNSDFEKLKKELDELVDAIEK 597
             +SKSSQMITFTF NG VATMRTSGTEPKIKYYAELCAPPGNSD E LKKELDELV AIE+
Sbjct:   546 TSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEHLKKELDELVGAIEE 605

Query:   598 YFFEPEKNKLQSKPE 612
             +FF+P+K  LQ K E
Sbjct:   606 HFFQPQKYNLQPKAE 620