| Nomenclature | Genomic Location |
| Symbol | Grm5 | Chromosome | 1 |
| Name | Metabotropic glutamate receptor 5 | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | 1: 14 Mbp |
| Molecular Function |
|
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a
phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
Molecular Function Terms:
binding
protein binding
receptor binding
G-protein-coupled receptor binding
molecular transducer activity
signal transducer activity
signaling receptor activity
transmembrane signaling receptor activity
receptor activity
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| Human Disease Association |
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No disease association.
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1 CTTAAACCATTCCCTAAAATGATCCTTCTGCTTGTTATCTTGTTATTGAAGGAAGATGTC
61 TGTGGCAACGGTGGCCTTTTGGTTTCTGCACAGTCCAATGAAAGAAGAGTGGTGGCCCAC
121 ATGCCGGGTGACATTATCATTGGAGCTTTGTTCTCTGTCCACCATCAGCCGTCCGTTGAC
181 AAAGTCCATGAGAGGAAATGTGGAGAGGTGAGAGAGCAATATGGCATCCAGAGAGTGGAG
241 GCAATGCTGCATACCCTAGATAGGATTAATCAAAACCAAACACTCTTGCCAAACATAACT
301 TTAGGTTGTGAGATCCGGGATTCATGCTGGCATTCAGCGGTCGCTCTTGAGCAAAGTATT
361 GAGTTCATCCGGGACTCTCTCATCTCAGCAGAAGAGGAACAAGGACTGATGAAATGTGTA
421 GATGGATCATCTTCTTCTTTCCATTCCAAGAAGCCTATCGTTGGTGTCATTGGGCCTGGG
481 TCTAGTTCTGTGGCAATCCAGGTGCAAAATCTGTTGCAACTTTTCAACATACCTCAGATT
541 GCCTACTCAGCCACAAGCATGGACTTAAGTGACAAGACCTTGTTCAAATATTTCATGAGA
601 GTTGTACCCTCAGATGCTCAACAGGCTCGCGCTATGGTGGACATTGTCAAGAGATACAAC
661 TGGACTTACGTATCTGCTGTACACACTGAAGGAAACTATGGTGAAAGTGGAATGGAAGCC
721 TTCAAAGACATGTCAGCCAAGGAAGGGATCTGCATTGCCCATTCCTATAAGATCTACAGC
781 AATGCCGGGGAACAGAGCTTTGACAAACTGCTGGAGAAGCTAAGAAGCCATTTACCCAAG
841 GCAAGAGTTGTGGCGTGCTTCTGTGAGGGCATGACTGTGCGAGGACTGCTTATGGCCATG
901 AGGCGCTTGGGGCTGGCTGGAGAATTCTTGCTGCTGGGCAGTGATGGCTGGGCAGACAGG
961 TACGACGTGACAGACGGATACCAGCGTGAAGCTGCTGGTGGAATTACAATCAAGCTCCAG
1021 TCTCCTGATGTCAAATGGTTTGATGATTATTACCTGCAGCTTCAACCAGATACCAATCAC
1081 CGAAACCCATGGTTTCAGGAATTTTGGCAACATCGATTCCAGTGCCGGCTAGCAGGGTCC
1141 CCACAGGAGAATCCAAAATTCAATAAGACATGCAGCAGTAATCTGACTTTAGAAACACAA
1201 CATGTGCAAGATTCAAAAATGGGCTTTGTGATTAATGCCATATACTCCATGGCATATGGC
1261 CTCCACAATATGCAGATGACATTGTGCCCAGGTTATGCGGGTCTTTGCGATGCTATGAAA
1321 CCTATTGATGGACGAAAGCTTCTGGAGGCTCTTATGAAGTCAAACTTCACTGGGGTGTCT
1381 GGGGACATGATCTCTTTTGATGAGAATGGAGATTCACCAGGACGGTACAGGTATGAGATT
1441 ATGAATTTTAAGAAAATGGGCAAGGACTACTTTGACTATATCAATGTTGGAAGTTGGGAC
1501 AATGGTGAACTAAAAATGGATGATGATGAAATCTGGTCAAAGAAGGTTACCATCATCAGA
1561 TCTGTCTGCAGTGAACCTTGTGAGAAAGGAGAGATCAAGGTAATCCGCAAAGGGGAAGTC
1621 AGTTGCTGTTGGACTTGCACACCTTGCAAAGAAAATGAATTTGTTTTCGATGAATACACC
1681 TGCAAGGCCTGTGACTTGGGTTCTTGGCCCAATGATCAGCTCACTGGTTGTGATTTAATT
1741 CCAGTTCAGTATCTGCGATGGGGTGATCCAGAGCCAATTGCAGCTGTTGTATTTGCCTGC
1801 TTGGGTCTCCTGGCCACCATGTTTGTTACTGCTGTGTTCATCCTGTATCGCGACACACCA
1861 GTTGTCAAGTCTTCAAGCCGAGAACTCTGCTACATCATCTTAGCTGGGATATTTTTGGGC
1921 TACCTGTGTACTTTTTGTCTTATTGCAAAACCTCAGAAGATCTATTGTTACCTACAACGA
1981 ATTGGCATTGGTCTTTCCCCTGCAATGAGCTACTCTGCTCTGGTGACAAAAACCAACCGG
2041 ATTGCACGGATCCTGGCTGGCAGCAAGAAGAAAATCTGCACCAAGAAACCTCGATTCATG
2101 AGCGCCTGTGCCCAATTGGTCATAGCATTTATCTTAATAGGCGTCCAGTTGGGCATCATT
2161 GTGGCTCTTTTCATAATGGAGCCCCCAGATATCAAGCACGATTTCCCAAGCATTCAAGAA
2221 GTATATCTGATATGCAACACCACCAACCTGGGGGTTGTGACTCCCCTTGGATACAATGGT
2281 TTGCTCATTTTAAGTTGCACCTTCTACGCATTCAAGACCAGAAATGTTCCAGCAAATTTC
2341 AATGAAGCCAAATATATTGCTTTCACCATGTACACTACTTGCATCATTTGGCTGGCTTTT
2401 GTCCCCATTTATTTCGGGAGCAACTATAAAATTATCACTATGTGTTTTTCGGTCAGCTTG
2461 AGTGCCACTGTAGCCCTTGGTTGCATGTTTGTGCCAAAAGTGTACATCATCCTTGCCAAG
2521 CCGGAGAGAAATGTACGCAGTGCATTTACCACCTCAACTGTGGTTCGCATGCATGTTGGG
2581 GATGGGAAGTCCTCTTCTGCTACCAGCCGGTCAAGCAGTTTGGTCAACCTGTGGAAGAGG
2641 AGGGGATCTTCGGGAGAGACCCTAAGGTACAAAGGCAGGAAGCTGGCCCAGCACAAGTCC
2701 GAAATAGAGTGTTTCACTCCAAAAGGGAGTATGGGAAATGGTGGGCGAGCGACAATGAGC
| Predicted Protein Product |
LKPFPKMILLLVILLLKEDVCGNGGLLVSAQSNERRVVAHMPGDIIIGALFSVHHQPSVD
KVHERKCGEVREQYGIQRVEAMLHTLDRINQNQTLLPNITLGCEIRDSCWHSAVALEQSI
EFIRDSLISAEEEQGLMKCVDGSSSSFHSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQI
AYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEA
FKDMSAKEGICIAHSYKIYSNAGEQSFDKLLEKLRSHLPKARVVACFCEGMTVRGLLMAM
RRLGLAGEFLLLGSDGWADRYDVTDGYQREAAGGITIKLQSPDVKWFDDYYLQLQPDTNH
RNPWFQEFWQHRFQCRLAGSPQENPKFNKTCSSNLTLETQHVQDSKMGFVINAIYSMAYG
LHNMQMTLCPGYAGLCDAMKPIDGRKLLEALMKSNFTGVSGDMISFDENGDSPGRYRYEI
MNFKKMGKDYFDYINVGSWDNGELKMDDDEIWSKKVTIIRSVCSEPCEKGEIKVIRKGEV
SCCWTCTPCKENEFVFDEYTCKACDLGSWPNDQLTGCDLIPVQYLRWGDPEPIAAVVFAC
LGLLATMFVTAVFILYRDTPVVKSSSRELCYIILAGIFLGYLCTFCLIAKPQKIYCYLQR
IGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILIGVQLGII
VALFIMEPPDIKHDFPSIQEVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANF
NEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAK
PERNVRSAFTTSTVVRMHVGDGKSSSATSRSSSLVNLWKRRGSSGETLRYKGRKLAQHKS
EIECFTPKGSMGNGGRATMS
| Protein Alignment to Mouse |
tr|Q4VA56|Q4VA56_MOUSE Grm5 protein (Fragment) OS=Mus musculus GN=Grm5 PE=2
SV=1
MGI:3645892 Vmn2r1 vomeronasal 2, receptor 1 (Chr 3)
Length = 1065
Score = 4317 (1524.7 bits), Expect = 0., P = 0.
Identities = 820/922 (88%), Positives = 852/922 (92%)
Query: 1 LKPFPKMXXXXXXXXX--KEDVCGNGGLLVSAQSNERRVVAHMPGDIIIGALFSVHHQPS 58
L FPKM KEDV G SAQS+ERRVVAHMPGDIIIGALFSVHHQP+
Sbjct: 29 LNSFPKMVLLLILSVLLLKEDVRG------SAQSSERRVVAHMPGDIIIGALFSVHHQPT 82
Query: 59 VDKVHERKCGEVREQYGIQRVEAMLHTLDRINQNQTLLPNITLGCEIRDSCWHSAVALEQ 118
VDKVHERKCG VREQYGIQRVEAMLHTL+RIN + TLLPNITLGCEIRDSCWHSAVALEQ
Sbjct: 83 VDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQ 142
Query: 119 SIEFIRDSLISAEEEQGLMKCVDGSSSSFHSKKPIVGVIGPGSSSVAIQVQNLLQLFNIP 178
SIEFIRDSLIS+EEE+GL++CVDGSSS F SKKPIVGVIGPGSSSVAIQVQNLLQLFNIP
Sbjct: 143 SIEFIRDSLISSEEEEGLVRCVDGSSS-FRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIP 201
Query: 179 QIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGM 238
QIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGM
Sbjct: 202 QIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGM 261
Query: 239 EAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLEKLRSHLPKARVVACFCEGMTVXXXXX 298
EAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL+KLRSHLPKARVVACFCEGMTV
Sbjct: 262 EAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLM 321
Query: 299 XXXXXXXXXEFLLLGSDGWADRYDVTDGYQREAAGGITIKLQSPDVKWFDDYYLQLQPDT 358
EFLLLGSDGWADRYDVTDGYQREA GGITIKLQSPDVKWFDDYYL+L+P+T
Sbjct: 322 AMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPET 381
Query: 359 NHRNPWFQEFWQHRFQCRLAGSPQENPKFNKTCSSNLTLETQHVQDSKMGFVINAIYSMA 418
N RNPWFQEFWQHRFQCRL G QEN K+NKTC+S+LTL T HVQDSKMGFVINAIYSMA
Sbjct: 382 NLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMA 441
Query: 419 YGLHNMQMTLCPGYAGLCDAMKPIDGRKLLEALMKSNFTGVSGDMISFDENGDSPGRYRY 478
YGLHNMQM+LCPGYAGLCDAMKPIDGRKLL++LMK+NFTGVSGDMI FDENGDSPGRY
Sbjct: 442 YGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRY-- 499
Query: 479 EIMNFKKMGKDYFDYINVGSWDNGELKMDDDEIWSKKVTIIRSVCSEPCEKGEIKVIRKG 538
EIMNFK+MGKDYFDYINVGSWDNGELKMDDDE+WSKK IIRSVCSEPCEKG+IKVIRKG
Sbjct: 500 EIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKG 559
Query: 539 EVSCCWTCTPCKENEFVFDEYTCKACDLGSWPNDQLTGCDLIPVQYLRWGDPEPIAAVVF 598
EVSCCWTCTPCKENE+VFDEYTCKAC LGSWP D LTGCDLIPVQYLRWGDPEPIAAVVF
Sbjct: 560 EVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVF 619
Query: 599 ACLGLLATMFVTAVFILYRDTPVVKSSSRELCYIILAGIFLGYLCTFCLIAKPQKIYCYL 658
ACLGLLAT+FVT +FI+YRDTPVVKSSSRELCYIILAGI LGYLCTFCLIAKP++IYCYL
Sbjct: 620 ACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYL 679
Query: 659 QRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILIGVQLG 718
QRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILI +QLG
Sbjct: 680 QRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLG 739
Query: 719 IIVALFIMEPPDIKHDFPSIQEVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA 778
IIVALFIMEPPDI HD+PSI+EVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA
Sbjct: 740 IIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA 799
Query: 779 NFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIIL 838
NFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIIL
Sbjct: 800 NFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIIL 859
Query: 839 AKPERNVRSAFTTSTVVRMHVGDGKXXXXXXXXXXLVNLWKRRGSSGETLRYKGRKLAQH 898
AKPERNVRSAFTTSTVVRMHVGDGK LVNLWKRRGSSGETLRYK R+LAQH
Sbjct: 860 AKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQH 919
Query: 899 KSEIECFTPKGSMGNGGRATMS 920
KSEIECFTPKGSMGNGGRATMS
Sbjct: 920 KSEIECFTPKGSMGNGGRATMS 941
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