Nomenclature | Genomic Location |
Symbol | Map2 | Chromosome | X |
Name | Microtubule-associated protein 2 | Linkage map | unknown |
Species | Dracomimus familiaris | Genome Coordinates | X: 34 Mbp |
Molecular Function |
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization.
They also seem to have a stiffening effect on microtubules.
Molecular Function Terms:
binding
protein binding
calmodulin binding
cytoskeletal protein binding
cytoskeletal regulatory protein binding
glycoprotein binding
dystroglycan binding
beta-dystroglycan binding
|
Human Disease Association |
No disease association.
|
1 ATGGCTGATGAACGGAAGGATGAAGCTAAAGCACCGCACTGGACCTCAAGTCAGCTAGCC
61 GAAGCTTCTTCCCACTCACATCCCCCAGAGATCAAGGAGCAAAGCAGTACAAGTGAAGGG
121 TTGGTCAGAAGTGCCAATGGATTTCCATACAGAGAGGATGAAGATGGGGGATATGGGGCA
181 CGTGGGCAACAGAGCTCATATTCCAGAACCAAAGAGAATGGAATCAATGGAGAAGTAGCA
241 ACTGGAGAGAAAGAAACTGCAGAAGAAGTATCTGCAAGGATAGTCCAAGTAGTAACAGCT
301 GAAGCTGTGGCAGTTCTGAAAGGTGAACAGGAAAAGGAAGCCCAGCACAAAGATCAGCCA
361 GCACCATTACCTTTAGGTAAAGAATATAATTGCAATTGCCCCCCTCCCCCCCCTCCCCCG
421 TCGGCCTCAGTAATATCCAGTCAAACAACTGCAGATTTATTTGCAGCCTCGAAGATGGAA
481 ATCCATGTCCAGGAAGGGACAGACCTTTTCGCAGCTGAGCCATTAGGCATGAAGGACTCA
541 GAGAAAGGAAGTAAGACTAGTGAGCAATCCTTACATGATGCCTTAGTTCTACAGCCAGCA
601 AAAACAGAATCTATACAAAGAGCAGAATCACCAGACGAAGAAGAGAAGACTCCTCCTACT
661 CTCCTCGAACAGACTTTGGATGCCAATCACCAAAAGCAGGAACTCAGGGGTTCTGTAAAA
721 ACAGATATTGATTCTACAAGAGACTCAGATCAACATCAAGAGCAAAAAGATTTGTCAACA
781 CAGTGGCACCAAGAAGGTCAAACAGATGAAATAGCCACCACATCCCAGAAATCTACCAGC
841 AAAGCATTACCCACAGAGTCTAAAGATTATCAAACTGATCTTAAAAGATATGACTTTCCC
901 TCTCCAGGAAGCATAGGTTCTTCCTCACTGTCCGAATTAACAATGGACACAAGATCTACA
961 GTTAAAACTATCTTTTCATCTGATACTCTGCCAGGTGCTCATCATAAATCTGGGTCAGTA
1021 GAGACTAACAAAAGAATACACATATCTACTGCTTCAGACATTGCCAAAGACCTTATGAAA
1081 GATCATAAAATGGACAAAGAGAAAATTAAAAAACAGGAAGAAGACTTTGCAATAGCAACT
1141 ATTCCTTCTTTACCACCAGTTACAGAAGAAACAAGTGTGCAGAATGTTCCTCTTTGGGAG
1201 GAAGAGAAAGATATGACAGAGGATGAAAGTGATGAAGAGGGGTACTCTGTTTCCAGTAGA
1261 CAAAAGCATAGAGCATTAGATGATCAAAGTTTTGTGGCTTGTGCTGACCAACCCACTAAA
1321 GGAGCCATAGGAAAAGAAGCTGAAAAAGAGGGAAAACACAGCATGGAGACTTTTGCTGAC
1381 AGATTCAGTCAGGAATTATTTCCTGAAAAAGTTGAAGCATCTTTAAATAGACATGCATTG
1441 TCTGAAATGGAGAGCCCCTCTACTGAACCAAGTGATGAAACTCTGCACAGAAAAGATTCT
1501 GGAAAGAATTGTAAAGATGCAGAATTTTCTGTTGGAGATTCTGTCACTCACAAAGTGCAG
1561 GTGGAAGAAGACAAGTCAGGAATGTCTACCTATTTTGAGACTTCTGCTCTTAAAGATGAA
1621 TCTGTAAAGAGTGACATACTACTGCATGGTAGTGATTACTATGAACTGAGTGACACTAAG
1681 GAACAGACCTATGACCCTTACCATAAAGATTTCCTTTTTGCTAAAAAAGACACTGAGGAA
1741 TATCAACCAGACTCGTACCAACTCCCCAGTATACCCACTCATGAAATAGGATACAGTACT
1801 CTTGCCCAGAGCTTCCCAGAAGATGAACCTAGAGAACCCAGTTCACCTAAAGAAAGAATA
1861 TACACAATTGACCCCAATGTTTATGGGGATAAGAGAGAACTCCACAATAAAAATAAGGAT
1921 GATCTAACTCTAAGCAGAAGCTTGGGGCTTGGTGGAAGATCTGCCATAGAGCAGAGGAGT
1981 ATGTCAATTAACCTACCAATGTCCTGCTTGGACTCTATAGCATTGGGGTTTAACTTTGGA
2041 CGTACACATGACCTTTCACCTCTAGGTTCAGACATTCTAGATAATGCTAGTGGAGATGAA
2101 GGTGATGACTATTTGCCAGTCACCACCCCAGCAGTAGAAAAAACTCCTACCTTCCCAACA
2161 GATAGCAGGGAAGAAGAAGAAGAAGTAGTAGTAGTAGAAGAAGAAGAAGACGAAAAAGAG
2221 AAAATTGAGGAGCCAATAATGAAAGAAGAAGGAGAGATTCAGGTGGAGCCCTCGTGCGAG
2281 TCACCCTTCCTGGCCAAAGATTACTATAAAAATGGGAACGTAATGGCTCCTGACTTACCT
2341 GAAATGTTAGACCTTGCTGGCACAAGGTCAAGACTGGCATCTGCGAGCACAGAAGCTGAG
2401 GGAGCACAGAGCAAGTCCATTCTTTCGGAGGGACCAGAAGAAGACAGCAGTACAACCCAG
2461 CACCTTATGAAAGATGAAAACCACATGACTCTAAAGGCTGACAGTCAACTGGAAGATTTA
2521 GGTTACTGTGTTTTCAATAAATACACAGTACCAATGCCATCACCAGTCCAAGACAGTGAG
2581 AATTTGACCGGAGAGAGCTGTCCCTTTGATGAGAAAATTAGAAGAGGTGTCATTACAGAT
2641 CTCTCACTAATAGAAGTGAAGTTGGCAGCTGCAGAGAGATCGAAAGAAGAAAAAGAGGCA
2701 TCCAGTGACTCAGTCCTTTTAGGCAAAGACTTTGAACAAGAGAGAAAAGCTATTGATAAA
2761 CTAGACACTGTGCTAGAAAAAAGTGAGGAACCTACTGATTCCAAAGAAGCCTATTCTTCT
2821 GAGGATGCTGAGCATACAAGAGTAAAGCCTGATTCAACTTTAGAAACTGTAGATGATAAA
2881 AGTCTAGCTGGAGTGGAAGAGAAAGTGTCATTGATAACTCAGAAAGAGGAAGATGACATT
2941 CATATCACTAAGACTGGCACACCAGAAATCTCTTGTAAACCCGACTATGATGCTATAAAG
3001 CATGATTTGGATTCTGCTGCTCTGCAAGTTGAACAGGAATATCAAAGTAAGTTAGGAGTT
3061 CATCCAGATGAATCTGTCTCAGGGCAGAGCACAGTGGATCGAGACAAGATCCCCTCTGTA
3121 TTGCCTGAAGAACCCATTGTATGTGCAAAATTAGAGCCATGCCCTATTAAGGATGCCACT
3181 AAATTGTCTGAAATTGAATTCAAAGAAAAAGGTGCTAAGCCTGATCTTGTGCATCAAGAA
3241 GCAGTAGATAAAGAAGAATCGTATGAGTCAAGTGGAGATAATGACCAAGCCCAAGAGGGT
3301 TTGCCTGGAGATACTTCAAAGCCATATGTTGGAAAAATAGAACCAGAAAGTCCATCACTC
3361 TCAGAAGAGACTGTGTCACAAGTGCTAGTAGAACAACAAGTTGTAGAAACAGAGGTATCA
3421 AAAGCTACTCCAGAAGAAGCAGCTGAAATTCAAATGGAGAACATACCGCAGTCAAAAACA
3481 GACCAAGTGGAGTCTCTGGAGTTAGCAGACTCTGTGAAAACTGAAGATTTAGTTCATCAT
3541 TTAGAATATGAGAAAAAAGATGTAGAAGGAGAACAACAGAAAGAGGTTAAGCAACCAGAA
3601 GAACATAAAGAGGTTAAGCAAGCAGAAGAACTCAAAGAAGACATTAAAGAAGCAGAAGAA
3661 TATGAGGAGACTCAGGCTATCCCTGGGGAACTACCTGAACTCAAAGGAGTAATAGAATCT
3721 GTTGTTACAATTGAGGATGACTTCATCACAATAGTACAGACAACGGTAGATGAGGGAGAT
3781 GCCAGCTCCCATAGTGTACGGTTTGCTGAAACCCAACAGGCTGACATTGAAGAGGAAGGC
3841 ATCCATCCTGAAGAGGAGGTAGACATGGAGGTGGTTGCTGACATCAAAGAAGAGAAAAAA
3901 GACACCTCTTTAGAAGCTCCTGGTTCTCCTGAGAGGGAAGAAGTCCCCTTAACTGATTAT
3961 AAAACAGAGACGTATGATGATTATAAGGACGAAACCACCATTGATGACTCGATCCTGGAC
4021 ACTGACAGCATATGGGTGGATACTCAAGATGATGATAGGAGCATCATGACAGAACAGTTA
4081 GAGACTGTTCCTAAAGAGGAGAAAGCAGAGAGAGAATTGCGGAGACCGTCTCTCGATAAG
4141 CATAAAAAAGAGAAAGCCTTAAAAACTGGGAGAGGCAGGATTTCTACTCCTGAAAGAAAA
4201 ATAGCTAAAAAGGAACCTAGCACAGTCTCCAGAGATGAAGTGAGAAGGAAAAAAGCTGTA
4261 TATAAGAAAGCTGAACTTTCTAAAAAAGCTGAAGTTCAGGCTCACTCTCCCTCCAGGAAA
4321 ATCATTTTAAAACCTGCTATCAAACACACTAGACCAACTCATCACTCCTGTGTTAAGCGG
4381 AAGCAGACAGCCGCTGCTGGTGAAACAAATCAAACTCCTGGGATGTTTAAGCAAGCAAAG
4441 GAAAAACTTTCAGATGGAATAATCAAGAGTCCTGAAAAGCGTTCCTCTTTACCAAGACCT
4501 TCTTCAATTCTTCCCACCCGGAGAGGCATATCAGCAGATAGAGAACGGGATGAGAACTCT
4561 TCCTCCTTGAACAGCACTATTTCATCGGCACGACGGACAACCAGATCAGAGCCTATCAGA
4621 AGCCGGACAGGAAAGAGTGGCACATCAACCCCAACTACTCCAGGATCCACTGCCATCACT
4681 CCTGGCACACCGCCTAGCTATTCCTCCCGTACTCCAGGCACTCCTGGCACCCCTAGCTAT
4741 TCTAGAACCCCTCACACTCCGGGTACCCCCAGATCTGCTATTCTGGTCCCCACTGAGAAG
4801 AAAGTTGCTATCATCCGCACGCCTCCGAAATCGCCAGGCACCCCAAAGCAACTACGACTC
4861 ATCAACCAGCCGCTGCCTGATCTCAAGAATGTCAGGTCCAAAATCGGGTCAACAGACAAT
4921 ATCAAATATCAACCTAAAGGAGGACAGATTCAGATTGTAACCAAGAAGATAGACCTGAGC
4981 CATGTGACTTCCAAATGTGGTTCACTGAAGAATATCCGCCATAGGCCAGGTGGGGGGCGA
5041 GTGAAAATCGAGAGTGTGAAACTGGATTTTAAAGAAAAGGCCCATGCCAAGGTTGGTTCG
5101 CTTGAAAATGCTCACCATGTACCTGGAGGAGGTCACATCAAGATTGACAGCCAGAAGCTC
5161 AATTTCCGAGAGCATGCTAAGGCCCGTGTGGACCATGGAGCAGAGATCATCACGCAGTCC
5221 CCAGGCCGATCCAGCGTGGCTTCTCCACGGAGGCTCAGCAACGTCTCCTCCTCTGGCAGC
5281 ATCAACCTCCTTGAATCTCCTCAGCTTGCTACCCTCGCTGAAGATGTCACTGCGGCCCTA
5341 GCTAAACAGGGCTTATGA
Predicted Protein Product |
MADERKDEAKAPHWTSSQLAEASSHSHPPEIKEQSSTSEGLVRSANGFPYREDEDGGYGA
RGQQSSYSRTKENGINGEVATGEKETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQP
APLPLGKEYNCNCPPPPPPPSASVISSQTTADLFAASKMEIHVQEGTDLFAAEPLGMKDS
EKGSKTSEQSLHDALVLQPAKTESIQRAESPDEEEKTPPTLLEQTLDANHQKQELRGSVK
TDIDSTRDSDQHQEQKDLSTQWHQEGQTDEIATTSQKSTSKALPTESKDYQTDLKRYDFP
SPGSIGSSSLSELTMDTRSTVKTIFSSDTLPGAHHKSGSVETNKRIHISTASDIAKDLMK
DHKMDKEKIKKQEEDFAIATIPSLPPVTEETSVQNVPLWEEEKDMTEDESDEEGYSVSSR
QKHRALDDQSFVACADQPTKGAIGKEAEKEGKHSMETFADRFSQELFPEKVEASLNRHAL
SEMESPSTEPSDETLHRKDSGKNCKDAEFSVGDSVTHKVQVEEDKSGMSTYFETSALKDE
SVKSDILLHGSDYYELSDTKEQTYDPYHKDFLFAKKDTEEYQPDSYQLPSIPTHEIGYST
LAQSFPEDEPREPSSPKERIYTIDPNVYGDKRELHNKNKDDLTLSRSLGLGGRSAIEQRS
MSINLPMSCLDSIALGFNFGRTHDLSPLGSDILDNASGDEGDDYLPVTTPAVEKTPTFPT
DSREEEEEVVVVEEEEDEKEKIEEPIMKEEGEIQVEPSCESPFLAKDYYKNGNVMAPDLP
EMLDLAGTRSRLASASTEAEGAQSKSILSEGPEEDSSTTQHLMKDENHMTLKADSQLEDL
GYCVFNKYTVPMPSPVQDSENLTGESCPFDEKIRRGVITDLSLIEVKLAAAERSKEEKEA
SSDSVLLGKDFEQERKAIDKLDTVLEKSEEPTDSKEAYSSEDAEHTRVKPDSTLETVDDK
SLAGVEEKVSLITQKEEDDIHITKTGTPEISCKPDYDAIKHDLDSAALQVEQEYQSKLGV
HPDESVSGQSTVDRDKIPSVLPEEPIVCAKLEPCPIKDATKLSEIEFKEKGAKPDLVHQE
AVDKEESYESSGDNDQAQEGLPGDTSKPYVGKIEPESPSLSEETVSQVLVEQQVVETEVS
KATPEEAAEIQMENIPQSKTDQVESLELADSVKTEDLVHHLEYEKKDVEGEQQKEVKQPE
EHKEVKQAEELKEDIKEAEEYEETQAIPGELPELKGVIESVVTIEDDFITIVQTTVDEGD
ASSHSVRFAETQQADIEEEGIHPEEEVDMEVVADIKEEKKDTSLEAPGSPEREEVPLTDY
KTETYDDYKDETTIDDSILDTDSIWVDTQDDDRSIMTEQLETVPKEEKAERELRRPSLDK
HKKEKALKTGRGRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAELSKKAEVQAHSPSRK
IILKPAIKHTRPTHHSCVKRKQTAAAGETNQTPGMFKQAKEKLSDGIIKSPEKRSSLPRP
SSILPTRRGISADRERDENSSSLNSTISSARRTTRSEPIRSRTGKSGTSTPTTPGSTAIT
PGTPPSYSSRTPGTPGTPSYSRTPHTPGTPRSAILVPTEKKVAIIRTPPKSPGTPKQLRL
INQPLPDLKNVRSKIGSTDNIKYQPKGGQIQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR
VKIESVKLDFKEKAHAKVGSLENAHHVPGGGHIKIDSQKLNFREHAKARVDHGAEIITQS
PGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
Protein Alignment to Mouse |
sp|P20357|MAP2_MOUSE Microtubule-associated protein 2 OS=Mus musculus GN=Map2
PE=1 SV=2
MGI:97175 Mtap2 microtubule-associated protein 2 (Chr 1)
Length = 1828
Score = 3159 (1117.1 bits), Expect = 0., Sum P(3) = 0.
Identities = 734/1448 (50%), Positives = 894/1448 (61%)
Query: 383 SLPPVTEETSVQNVPLWEEEKDMTEDESDEEGYSVSSRQKHRALDDQSFVACADQPTKGA 442
S P V E T + P + + D S EE + + + DD++ V T+ +
Sbjct: 422 SAPSVQEPTLTETEP--QTKLDEKSTVSIEEAVA-KKEESFKLRDDKTGVI--QTSTEQS 476
Query: 443 IGKEAEKEGKHSMETFADRFSQELFPEKVEASLNRHALSE--MESPSTEPSDETLHRKDS 500
KE +K +H++ D Q+ FP +E ++ A++ + ++EP + R+
Sbjct: 477 FSKEDQKGQEHTI----DELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQ 532
Query: 501 G----KNC-KDAEFSVGDSVTHKVQVE--EDKSGMSTYFETSALKDESVKSDILLHGSDY 553
G K K+ G + +V++ EDKSGMS YFETSALK++ +S L GSDY
Sbjct: 533 GLFEEKTADKNKLEGAGSATIAEVEMPFYEDKSGMSKYFETSALKEDMTRSTEL--GSDY 590
Query: 554 YELSDTKEQTYDPYHKDFLFAKK--DTEEYQPDSYQLPSIPTHEIGYSTLAQSF----PE 607
YELSD++ + D + K D +E Q + Q PS P E GYSTLAQS+ P
Sbjct: 591 YELSDSRGSAQESL--DTISPKNQHDEKELQAKASQ-PSPPAQEAGYSTLAQSYTPDHPS 647
Query: 608 DEPREPSSPKERIYTIDPNVYGDKRELHNKNKDDLTXXXXXXXXXXXAIEQRSMSINLPM 667
+ P EPSSP+ER++TIDP VYG+KR+LH+KNKDDLT AIEQRSMSINLPM
Sbjct: 648 ELPEEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPM 707
Query: 668 SCLDSIALGFNFGRTHDLSPLGSDILDNASG--DEGDDYLPVTTPAVEKTPTFPTDSRXX 725
SCLDSIALGFNFGR HDLSPL SDIL N SG DEGDDYLP TTPAVEK P FP +S+
Sbjct: 708 SCLDSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDDYLPPTTPAVEKMPCFPIESKEE 767
Query: 726 XXXXXXXXXXXXXXXXXXXXXXXXXXXXQVEPSCESPFLAKDYYKNGNVMAPDLPEMLDL 785
QVE S ESPF AK+YYKNG VMAPDLPEMLDL
Sbjct: 768 EDKAEQAKVTGGQTI-------------QVETSSESPFPAKEYYKNGTVMAPDLPEMLDL 814
Query: 786 AGTRSRLASASTEAEGAQSKSILSEGPEEDSSTTQHLMKDENHMTLKADSQLEDLGYCVF 845
AGTRSRLAS S +AE A+ KS+ SE +SST+ + DE+ +T+K DSQLED+GYCVF
Sbjct: 815 AGTRSRLASVSADAEVARRKSVPSEAMLAESSTSLPPVADESPVTVKPDSQLEDMGYCVF 874
Query: 846 NKYTVPMPSPVQDSENLTGESCPF----DEKIRRGVITDLSLIEVKLXXXXXXXXXXXX- 900
NKYTVP+PSPVQDSENL+GES F D+K+RR + TDLSLIEVKL
Sbjct: 875 NKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLAAAGRVKDEFTAE 934
Query: 901 -------XXXXVLLGKDFEQERKAIDKLDTVLEKSEEPTDSKEAYSSEDAEHTRVKPDST 953
L ++F+ +RKA DKLDTVLEKSEE DSKE + +V+
Sbjct: 935 KEASPPTSADKSRLSREFDHDRKANDKLDTVLEKSEEHIDSKEHAKESEEMGGKVELFGL 994
Query: 954 LETVDDKSLAGVEEKVSLITQKEEDDIH-ITKTGTPEISCKPD----YDAIKHDLDSAAL 1008
T D S + +K E + + + E + K D + A K + +
Sbjct: 995 GITYDQASTKELITTKDTSPEKTEKGLSSVPEVAEVEPTTKADQGLDFAATKAEPSQLDI 1054
Query: 1009 QVEQEYQSKLGVHPD--ESVSGQSTVDRD-KIPSVLPEEPIVCAKLEPCPIKDATKLSEI 1065
+V Q G++ D +++ + V ++ + S P+E +E IK+ K++E
Sbjct: 1055 KVSDFGQMASGMNVDAGKAIELKFEVAQELTLSSEAPQEADSFMGVESGHIKEGGKVNET 1114
Query: 1066 EFKEKGAKPDLVHQEAVDKEESYESSGDNDQAQEGLPGDTSKPYVGKIE--PESPXXXXX 1123
E KEK KPDLVHQEAVDKEESYESSG++ E L ++ KP GK E PE+
Sbjct: 1115 EVKEKVTKPDLVHQEAVDKEESYESSGEH----ESLTMESLKPDEGKKETSPETSLIQDE 1170
Query: 1124 XXXXXXXXXXXXX-XXXXKATPEEAAEIQME--NIPQSKTDQVESLELADSVKTEDLVHH 1180
+ +E E+QME +P+ ++ + + S T+
Sbjct: 1171 VALKLSVEIPCPPPVSEADLSTDEKGEVQMEFIQLPKEESTETPDIPAIPSDVTQPQPEA 1230
Query: 1181 LEYEKKDVEGEQQKEVKQPEEHKEV---KQAXXXXXXXXXXXXXXXTQAIPGELPELKGV 1237
+ E +V E++ E++ E+ ++ + PGEL KGV
Sbjct: 1231 IVSEPAEVPSEEE-EIEAGGEYDKLLFRSDTLQISDLLVSESREEFVETCPGEL---KGV 1286
Query: 1238 IESVVTIEDDFITIVQTTVDEGDASSHSVRFAETQQADIXXXXXXXXXXVDMEVVADIKE 1297
+ESVVTIEDDFIT+VQTT DEG++ SHSVRFA Q + +++E+ A+ +
Sbjct: 1287 VESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEEERRPRPHDEELEIEMAAEAQA 1346
Query: 1298 EKKDTSLEAPGSPEREEVPLXXXXXXXXXXXXXXXXXXXXXXXXXXXWVDTQDDDRSIMT 1357
E KD S +AP +PE+EEV WVDTQDDDRSI+T
Sbjct: 1347 EPKDGSPDAPATPEKEEVAFSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSILT 1406
Query: 1358 EQLETVPKEEKAERELRRPSLDKHKKEKALKTGRGRISTPERKIAKKEPSTVSRDEVRRK 1417
EQLET+PKEE+AE++ RRPSL+KH+KEK KTGRGRISTPERK+AKKEPSTVSRDEVRRK
Sbjct: 1407 EQLETIPKEERAEKDARRPSLEKHRKEKPFKTGRGRISTPERKVAKKEPSTVSRDEVRRK 1466
Query: 1418 KAVYKKAELSKKAEVQAHSPSRKIILKPAIKHTRPTHHSCVKRKQTAAAGETNQTPGMFK 1477
KAVYKKAEL+KK+EVQAHSPSRK+ILKPAIK+TRPTH SCVKRK TAA+G+ Q PG FK
Sbjct: 1467 KAVYKKAELAKKSEVQAHSPSRKLILKPAIKYTRPTHLSCVKRKTTAASGDLAQAPGAFK 1526
Query: 1478 QAKEKLSDGIIKSPEKXXXXXXXXXXXXXXXGISADRERDENXXXXXXXXXXXXXXXXXE 1537
QAK+K++DGI KSPEK G+S DRE EN E
Sbjct: 1527 QAKDKVTDGISKSPEKRSSLPRPSSILPPRRGVSGDRE--ENSFSLNSSISSARRTTRSE 1584
Query: 1538 PIRSRXXXXXXXXXXXXXXXXXXXXXXXXYSSRTPGTPGTPSYSRTPHTPGTPRSAILVP 1597
PIR R YSSRTPGTPGTPSY P TPGTP+S ILVP
Sbjct: 1585 PIR-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSY---PRTPGTPKSGILVP 1640
Query: 1598 TEKKVAIIRTPPKSPGTPKQLRLINQPLPDLKNVRSKIGSTDNIKYQPKGGQIQIVTKKI 1657
+EKKVAIIRTPPKSP TPKQLRLINQPLPDLKNV+SKIGSTDNIKYQPKGGQ+QIVTKKI
Sbjct: 1641 SEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKI 1700
Query: 1658 DLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAHAKVGSLENAHHVPGGGHIKIDS 1717
DLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA AKVGSL+NAHHVPGGG++KIDS
Sbjct: 1701 DLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDS 1760
Query: 1718 QKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVT 1777
QKLNFREHAKARVDHGAEIITQSP RSSVASPRRLSNVSSSGSINLLESPQLATLAEDVT
Sbjct: 1761 QKLNFREHAKARVDHGAEIITQSPSRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVT 1820
Query: 1778 AALAKQGL 1785
AALAKQGL
Sbjct: 1821 AALAKQGL 1828
Score = 618 (222.6 bits), Expect = 0., Sum P(3) = 0.
Identities = 143/303 (47%), Positives = 174/303 (57%)
Query: 1 MADERKDEAKAPHWTSSQLAEASSHSHPPEIKEQSSTSEGLVRSANGFPYREDEDGGYGA 60
MADERKDE KAPHWTS+ L EA++H H PE+K+Q EGL R+ANGFPYRE+E+G +G
Sbjct: 1 MADERKDEGKAPHWTSASLTEAAAHPHSPEMKDQGGAGEGLSRNANGFPYREEEEGAFGE 60
Query: 61 RGQQSSYSRTKENGINGEVATGEKETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQP 120
Q +YS TKENGINGE+ + ++ETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQP
Sbjct: 61 HRSQGTYSDTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQP 120
Query: 121 APLPLGKEYNCNCXXXXXXXSASVISSQTTADLFAASKMEIHVQEGTDLFAAEPL--GMK 178
A LPL E N AS ++ DL ASKME QE AEPL G
Sbjct: 121 AALPLAAEETANLPPSPPPSPASEQTATVEEDLLTASKMEFPEQEKFPSSFAEPLDKGEM 180
Query: 179 DSEKGSKTSEQSLHDALVLQPAKTESIQRAESPDEEEKTPPTLLEQTLDAN--HQKQELR 236
+ + SK E H ALV +KT ++ E EK PP QT N +KQ
Sbjct: 181 EFKMPSKPGEDFEHAALVPDTSKTPQDKKDLQGMEGEKLPPVPFAQTFGTNLEDRKQSTE 240
Query: 237 GS-VKTDIDSTRDSDQHQEQKDLSTQWHQEGQTDEIATTSQKSTSKALPTESKDYQTDLK 295
S V I + + +E KD + E + DE + S P KD D+
Sbjct: 241 PSIVMPSIGLSAEPPAPKEPKDWFIEMPTESKKDEWGLAAPISPGPLTPMREKDVLEDIP 300
Query: 296 RYD 298
R++
Sbjct: 301 RWE 303
Score = 64 (27.6 bits), Expect = 0., Sum P(2) = 0.
Identities = 19/72 (26%), Positives = 29/72 (40%)
Query: 3 DERKDEAKAPHWTSSQLAEASSHSHPPEIKEQSSTSEGLVRSANGFPYREDEDGGYGARG 62
D+ K E AP L E + E K S E + + F R+D+ G
Sbjct: 415 DQEKKETSAPSVQEPTLTETEPQTKLDE-KSTVSIEEAVAKKEESFKLRDDKTGVIQTST 473
Query: 63 QQSSYSRTKENG 74
+QS +S+ + G
Sbjct: 474 EQS-FSKEDQKG 484
Score = 42 (19.8 bits), Expect = 8.9e-54, Sum P(3) = 8.9e-54
Identities = 17/56 (30%), Positives = 23/56 (41%)
Query: 1379 DKHKKE-KALKTGRGRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAELSKKAEVQ 1433
D+ KKE A ++ E + E STVS +E KK K K +Q
Sbjct: 415 DQEKKETSAPSVQEPTLTETEPQTKLDEKSTVSIEEAVAKKEESFKLRDDKTGVIQ 470
Score = 41 (19.5 bits), Expect = 0., Sum P(3) = 0.
Identities = 6/17 (35%), Positives = 12/17 (70%)
Query: 384 LPPVTEETSVQNVPLWE 400
L P+ E+ ++++P WE
Sbjct: 287 LTPMREKDVLEDIPRWE 303
Score = 37 (18.1 bits), Expect = 2.3e-53, Sum P(3) = 2.3e-53
Identities = 8/19 (42%), Positives = 11/19 (57%)
Query: 837 LEDLGYCVFNKYTVPMPSP 855
LED+ ++ PMPSP
Sbjct: 296 LEDIPRWEGKQFDSPMPSP 314
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