| Nomenclature | Genomic Location |
| Symbol | Prtg | Chromosome | X |
| Name | Protogenin | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | X: 32 Mbp |
| Molecular Function |
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May play a role in anteroposterior axis elongation.
Molecular Function Terms:
(none)
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| Human Disease Association |
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No disease association.
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1 GCCATGCCTGCCTTTGAGCTGCAGCCGCTTCCGGCCAAGGTCCCTGAGGGTGGAGTGGCC
61 CGCTTTGCCTGCAAGGTCTCTTCCGTCCCTCCGGCCGTTGTCACCTGGGAACGCAACCGC
121 ACCGCACTCCCCATCGCCCTGGACAGGATCACGGCCTTGCCCTCCGGAGTGCTGCAAATC
181 TACGGCGTCCAGCCGCAGGACGCGGGGAGCTACCGCTGCGTGGCCACGGCCCCCGCCCAC
241 CGCAGGAAGAGCGCCGAGGCCACGCTCACCGTCCTCCCAGCCTCCAACGCCAAGCTCCTC
301 CACAAGCCTTCCATCATCGCCGGTCCGGAGAACGTCACGGCTTCCCTCCACCAGACGGTC
361 ATCTTCGAGTGCGTGGCCACCGGGAACCCAAAGCCCATCATTTCCTGGAGCCGCTTGGAC
421 CACAAGCCCATTGACGTCTTCAACACGCGTGTCCTGGGGAATGGGAACCTCATGATCTCC
481 GACGTGAAGGCGCCCCACACCGGGGTCTACATCTGCCGCGCCACCACGCCCGGCACACGC
541 AACTTCACCACCGCCGCCGCCACCCTGACTGTCCTGGCGCCGCCTTCGTTCGTGGAGTGG
601 CCGGAGAGCTTGACCAGGCCGCGGGCCGGCACCGCCCGCTTTGGCTGCCAGGCGGAAGGC
661 ATCCCGGCCCCAAAGGTCTCCTGGCTGAAGAACGGGCGCAAGGTCCACTCCAACGGCCGG
721 ATCAAGATGTACAACAGCAAACTGGTCATCAACCAGATCATCCCGGAGGACGATGCCATC
781 TACCAGTGCCTGGCCGAGAACAGCCAGGGCTCGGTCCTGGCTCGGGCCAGGCTGACCGTG
841 GTCCTGTCCGAAGACCGGCCCAGCGCCCCCTGCAACGTCCACGCCGAGACCGTCTCCAGC
901 TCCGCCATCCTGCTGGCCTGGGAGCGGCCGCAGTACAACGCCGACAAGGTCATCGCCTAC
961 TCCGTCCACTACATGAAGGCCGAAGGT
| Predicted Protein Product |
AMPAFELQPLPAKVPEGGVARFACKVSSVPPAVVTWERNRTALPIALDRITALPSGVLQI
YGVQPQDAGSYRCVATAPAHRRKSAEATLTVLPASNAKLLHKPSIIAGPENVTASLHQTV
IFECVATGNPKPIISWSRLDHKPIDVFNTRVLGNGNLMISDVKAPHTGVYICRATTPGTR
NFTTAAATLTVLAPPSFVEWPESLTRPRAGTARFGCQAEGIPAPKVSWLKNGRKVHSNGR
IKMYNSKLVINQIIPEDDAIYQCLAENSQGSVLARARLTVVLSEDRPSAPCNVHAETVSS
SAILLAWERPQYNADKVIAYSVHYMKAEG
| Protein Alignment to Mouse |
sp|Q2EY15|PRTG_MOUSE Protogenin OS=Mus musculus GN=Prtg PE=2 SV=1
MGI:2444710 Prtg protogenin homolog (Gallus gallus) (Chr 9)
Length = 1191
Score = 1361 (484.2 bits), Expect = 9.0e-140, P = 9.0e-140
Identities = 252/326 (77%), Positives = 285/326 (87%)
Query: 4 AFELQPLPAKVPEGGVARFACKVSSVPPAVVTWERNRTALPIALDRITALPSGVLQIYGV 63
AFE+ P+ +V EGGVARF+CK+SS PPAV+TWE NRTALP +DR+TALPSGVLQIY V
Sbjct: 130 AFEVHPVSTEVHEGGVARFSCKISSTPPAVITWEFNRTALPTTMDRVTALPSGVLQIYDV 189
Query: 64 QPQDAGSYRCVATAPAHRRKSAEATLTVLPASNAKLLHKPSIIAGPENVTASLHQTVIFE 123
P+DAG+YRCVA AH+RKS EA+LT++ A+ + + P+IIA P+NVTASLHQTV+ E
Sbjct: 190 GPEDAGNYRCVAATIAHKRKSMEASLTIVAANETRSFYMPTIIASPQNVTASLHQTVVLE 249
Query: 124 CVATGNPKPIISWSRLDHKPIDVFNTRVLGNGNLMISDVKAPHTGVYICRATTPGTRNFX 183
C+ATG P+PIISWSRLDHK IDVFNTRVLGNGNL+ISDVK H GVY+CRATTPGTRNF
Sbjct: 250 CMATGYPRPIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFT 309
Query: 184 XXXXXXXXXXPPSFVEWPESLTRPRAGTARFGCQAEGIPAPKVSWLKNGRKVHSNGRIKM 243
PPSFVEWPESLTRPRAGTARF CQAEGIP+PK+SWLKNGR++HSNGRIKM
Sbjct: 310 VAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKM 369
Query: 244 YNSKLVINQIIPEDDAIYQCLAENSQGSVLARARLTVVLSEDRPSAPCNVHAETVSSSAI 303
YNSKLVINQIIPEDDAIYQC+AENSQGSVL+RARLTVV+SEDRPSAP NVHAET+SSSAI
Sbjct: 370 YNSKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSSAI 429
Query: 304 LLAWERPQYNADKVIAYSVHYMKAEG 329
LLAWERP YN+DKVIAYSVHYMKAEG
Sbjct: 430 LLAWERPLYNSDKVIAYSVHYMKAEG 455
Score = 159 (61.0 bits), Expect = 9.1e-12, Sum P(2) = 9.1e-12
Identities = 75/296 (25%), Positives = 114/296 (38%)
Query: 5 FELQPLPAKVPEGGVARFACKVSSVPPAVVTWERNRTALPIALDRITALPSGVLQIYGVQ 64
F +P A V C+ P VTW +N L RI L +G L I V+
Sbjct: 35 FMKEPQDATVTRKDPVVLDCQAHGEGPIKVTWLKNGAKLS-ENKRIQVLSNGSLYISEVE 93
Query: 65 PQ-----DAGSYRCVATAPAHRRKSAEATLTVLPASNAKLLHKPSIIAGPENVTASLHQT 119
+ D G Y+C+A S +A LT L +A +H P V+ +H+
Sbjct: 94 GRRGEQSDEGFYQCLAVNKYGAILSQKAHLT-LSTISAFEVH-------P--VSTEVHEG 143
Query: 120 VI--FECVATGNPKPIISWS-RLDHKPIDVFNTRVLGNGNLMISDVKAPHTGVYICRATT 176
+ F C + P +I+W P + L +G L I DV G Y C A T
Sbjct: 144 GVARFSCKISSTPPAVITWEFNRTALPTTMDRVTALPSGVLQIYDVGPEDAGNYRCVAAT 203
Query: 177 PGTRNFXXXXXXXXXXXP-------PSFVEWPESLTRPRAGTARFGCQAEGIPAPKVSWL 229
+ P+ + P+++T T C A G P P +SW
Sbjct: 204 IAHKRKSMEASLTIVAANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYPRPIISWS 263
Query: 230 KNGRKVHS--NGRIKMYNSKLVINQIIPEDDAIYQCLAEN--SQGSVLARARLTVV 281
+ K N R+ + N L+I+ + + +Y C A ++ +A A LTV+
Sbjct: 264 RLDHKSIDVFNTRV-LGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMATLTVL 318
Score = 121 (47.7 bits), Expect = 1.8e-07, Sum P(2) = 1.8e-07
Identities = 46/189 (24%), Positives = 75/189 (39%)
Query: 109 PENVTASLHQTVIFECVATGNPKPIISWSRLDHKPIDVFNTRVLGNGNLMISDVKAPH-- 166
P++ T + V+ +C A G ++W + K + +VL NG+L IS+V+
Sbjct: 39 PQDATVTRKDPVVLDCQAHGEGPIKVTWLKNGAKLSENKRIQVLSNGSLYISEVEGRRGE 98
Query: 167 ---TGVYICRATTP-GTRNFXXXXXXXXXXXPPSFVEWPESLTRPRAGTARFGCQAEGIP 222
G Y C A G +F P S G ARF C+ P
Sbjct: 99 QSDEGFYQCLAVNKYGA--ILSQKAHLTLSTISAFEVHPVSTEVHEGGVARFSCKISSTP 156
Query: 223 APKVSWLKNGRKVHSN-GRIKMYNSKLV-INQIIPEDDAIYQCLAEN-SQGSVLARARLT 279
++W N + + R+ S ++ I + PED Y+C+A + A LT
Sbjct: 157 PAVITWEFNRTALPTTMDRVTALPSGVLQIYDVGPEDAGNYRCVAATIAHKRKSMEASLT 216
Query: 280 VVLSEDRPS 288
+V + + S
Sbjct: 217 IVAANETRS 225
Score = 85 (35.0 bits), Expect = 0.0016, Sum P(2) = 0.0016
Identities = 22/75 (29%), Positives = 36/75 (48%)
Query: 1 AMPAFELQPLPAKVPEGGVARFACKVSSVPPAVVTWERNRTALPIALDRITALPSGVLQI 60
A P+F P P G ARF C+ +P ++W +N + + RI S ++ I
Sbjct: 319 APPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIH-SNGRIKMYNSKLV-I 376
Query: 61 YGVQPQDAGSYRCVA 75
+ P+D Y+C+A
Sbjct: 377 NQIIPEDDAIYQCMA 391
Score = 72 (30.4 bits), Expect = 9.1e-12, Sum P(2) = 9.1e-12
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 287 PSAPCNVHAETVSSSAILLAWERPQYNADKVIAYSV 322
P P +++A+ +SS+I L W RP + +VI Y++
Sbjct: 716 PPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTI 751
Score = 54 (24.1 bits), Expect = 6.6e-10, Sum P(2) = 6.6e-10
Identities = 17/78 (21%), Positives = 36/78 (46%)
Query: 249 VINQIIPEDDAIYQCLAENSQGSVLARARLTVVLSEDRPSAPCNVHAETVSSSAILLAW- 307
+I+ + P+ + + +A G+ +T ED P P + + S + IL++W
Sbjct: 473 IIDDLEPDSNYTFYIVAYMPLGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILVSWL 532
Query: 308 ERP-QYNADKVIAYSVHY 324
P +Y +V+ Y + +
Sbjct: 533 PIPAKYRRGQVVLYRLSF 550
Score = 42 (19.8 bits), Expect = 1.1e-08, Sum P(2) = 1.1e-08
Identities = 10/43 (23%), Positives = 16/43 (37%)
Query: 282 LSEDRPSAPCNVHAETVSSSAILLAWERPQYNADKVIAYSVHY 324
L E P V + L++W+ P V Y++ Y
Sbjct: 809 LPEAPTGPPVGVKVTLIEDDTALVSWKPPDGPETVVTRYTILY 851
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