Home Search Reports Help

Gene Model: Cs

NomenclatureGenomic Location
SymbolCsChromosomeX
NameCitrate synthase, mitochondrialLinkage mapunknown
SpeciesDracomimus familiarisGenome CoordinatesX: 50 Mbp

Molecular Function

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Molecular Function Terms:

catalytic activity
   transferase activity
      transferase activity, transferring acyl groups
         transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Human Disease Association

No disease association.

Predicted Transcript
     1 AAATATTTACACACCTCCTCTTTTTCCTTACAGAACTCATCATGCATCATTTTTGCTGCA
    61 AGACATGCCAGCGCTTCCACGAATTTGAAAGACGTTCTTGCAAACATGATCCCCAAAGAG
   121 CAAGCAAGACTGAAAAGCTTCAGACAACAATATGGGAGCACAGTTATTGGTCAAATCACT
   181 GTGGATATGCTCTATGGTGGCATGAGAGGCATGAAAGGGCTAATATACGAGACCTCAGTT
   241 TTGGACCCTGATGAGGGCATCCGTTTCCGTGGCTACAGCATTCCCGAGTGCCAGAAGCTG
   301 TTGCCCAAAGCCCCAGGAGGCGCAGAACCTCTTCCTGAAGGACTGTTCTGGTTGCTGGTG
   361 ACAGGAGAAATCCCCTCACAAGAACAGGTGAGCTGGCTGTCTCGAGAGTGGGCCAAGAGG
   421 GCAGCCCTGCCTTCCCATGTGGTGACCATGCTGGACAATTTCCCCACCAATCTTCACCCC
   481 ATGTCACAACTCAGTGCCGCTGTCACCGCCCTCAACAGTGAGAGTACTTTTGCCCGCGCC
   541 TACTCCGAGGGAATCAGTCGGACCAAGTACTGGGAGTTCATCTATGAAGACTCCATGGAC
   601 TTGATTGCCAAGCTGCCATGTATTGCTGCAAAGATCTACCGTAACCTGTACCGTGAGGGC
   661 AGTAGCATTGGCGCCATTGACCCTGCCTTAGACTGGTCACACAACTTCACCAACATGCTG
   721 GGTTACAATGATCCCCAGTTCATTGAACTTATGCGACTCTACCTCACCATTCACAGTGAC
   781 CATGAGGGTGGGAACGTCAGTGCACACACTAGCCATTTGGTGGGCAGTGCCCTCTCCGAT
   841 CCTTACTTGTCTTTTGCTGCAGCCATGAATGGTTTGGCTGGGCCACTCCATGGTCTTGCA
   901 AATCAGGAAGTGCTGGTGTGGTTGACCAGCCTGCAGAAGGAGCTGGGGGAAGATGTGTCT
   961 GATGAAAAGCTGAGGGATTTCATTTGGAACACCTTGAACTCTGGCAGGGTGGTTCCTGGC
  1021 TATGGCCATGCAGTGTTGAGGAAGACGGATCCCCGCTACACTTGCCAGAGAGAATTTGCC
  1081 CTCAAGCACCTTCCCAAAGATCCTCTCTTCAAGCTGGTGGCCCAGCTGTACAAGATTGTC
  1141 CCTAATGTGCTGCTGGAGCAAGGCAAAGCCAAGAACCCTTGGCCCAATGTGGATGCACAT
  1201 AGTGGGGTCCTGTTACAGTACTACGGCATGAAGGAGATGAACTACTACACTGTGCTATTT
  1261 GGTGTGTCTCGGGCCCTAGGTGTTCTCTCGCAACTCATCTGGAGTCGATCCCTTGGCTTC
  1321 CCACTGGAGAGACCGAAGTCCATGAGCACAGATGGGCTGATGGAGCTTGTGGGTGCCAAG
  1381 TCGGGTTAG

Predicted Protein Product
KYLHTSSFSLQNSSCIIFAARHASASTNLKDVLANMIPKEQARLKSFRQQYGSTVIGQIT
VDMLYGGMRGMKGLIYETSVLDPDEGIRFRGYSIPECQKLLPKAPGGAEPLPEGLFWLLV
TGEIPSQEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESTFARA
YSEGISRTKYWEFIYEDSMDLIAKLPCIAAKIYRNLYREGSSIGAIDPALDWSHNFTNML
GYNDPQFIELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLA
NQEVLVWLTSLQKELGEDVSDEKLRDFIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFA
LKHLPKDPLFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMKEMNYYTVLF
GVSRALGVLSQLIWSRSLGFPLERPKSMSTDGLMELVGAKSG
Protein Alignment to Mouse
sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial OS=Mus musculus GN=Cs
            PE=1 SV=1
      MGI:88529 Cs citrate synthase (Chr 10)
        Length = 464

 Score = 2173 (770.0 bits), Expect = 8.1e-226, P = 8.1e-226
 Identities = 403/457 (88%), Positives = 435/457 (95%)

Query:     5 TSSFSLQNSSCIIFAARHASAS-TNLKDVLANMIPKEQARLKSFRQQYGSTVIGQITVDM 63
             T     +NSSC++ AARHASAS TNLKDVL+N+IPKEQAR+K+F+QQ+G TV+GQITVDM
Sbjct:     8 TRLLGAKNSSCLVLAARHASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDM 67

Query:    64 LYGGMRGMKGLIYETSVLDPDEGIRFRGYSIPECQKLLPKAPGGAEPLPEGLFWLLVTGE 123
             +YGGMRGMKGL+YETSVLDPDEGIRFRGYSIPECQK+LPKA GG EPLPEGLFWLLVTG+
Sbjct:    68 MYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQ 127

Query:   124 IPSQEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESTFARAYSE 183
             +P++EQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAA+TALNSES FARAY+E
Sbjct:   128 MPTEEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAE 187

Query:   184 GISRTKYWEFIYEDSMDLIAKLPCIAAKIYRNLYREGSSIGAIDPALDWSHNFTNMLGYN 243
             G++R KYWE IYED MDLIAKLPC+AAKIYRNLYREGSSIGAID  LDWSHNFTNMLGY 
Sbjct:   188 GMNRAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYT 247

Query:   244 DPQFIELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQE 303
             DPQF ELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQE
Sbjct:   248 DPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQE 307

Query:   304 VLVWLTSLQKELGEDVSDEKLRDFIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKH 363
             VLVWLT LQKE+G+DVSDEKLRD+IWNTLNSGRVVPGYGHAVLRKTDPRY+CQREFALKH
Sbjct:   308 VLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH 367

Query:   364 LPKDPLFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVS 423
             LPKDP+FKLVAQLYKIVPN+LLEQGKAKNPWPNVDAHSGVLLQYYGM EMNYYTVLFGVS
Sbjct:   368 LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVS 427

Query:   424 RALGVLSQLIWSRSLGFPLERPKSMSTDGLMELVGAK 460
             RALGVL+QLIWSR+LGFPLERPKSMSTDGLM+ V +K
Sbjct:   428 RALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSK 464