| Nomenclature | Genomic Location |
| Symbol | Mdh2 | Chromosome | 2 |
| Name | Malate dehydrogenase 2,
NAD (mitochondrial) | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | 2: 29 Mbp |
| Molecular Function |
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(S)-malate + NAD+ = oxaloacetate + NADH.
Molecular Function Terms:
binding
protein binding
protein self-association
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
malate dehydrogenase activity
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| Human Disease Association |
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No disease association.
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1 ATGTATTCCCGGCTTTCCCTCCAGGCCGCTGCCTTGACCCTCCGGAGAGGCTTCACTTCC
61 TCCTCCCAGAGCAATGCGAAAGTGGCTGTGCTGGGTGCGTCTGGTGGAATTGGGCAGCCT
121 CTCTCCCTCTTGCTGAAGAACAGCCCCTTGGTCAGTCACCTGAGCCTCTATGATATCGCA
181 CACACTCCTGGTGTGGCTGCCGACCTCAGCCATATCGAAACCAGAGCCGAAGTGAAAGGT
241 TTTTTAGGACCCGAACAACTGCCGGAGTCGCTAAAAGGCTGCGAAGTTGTCGTGATCCCT
301 GCCGGAGTCCCTAGAAAACCAGGCATGACCCGTGATGACCTCTTCAACACAAATGCCACC
361 ATTGTAGCCAACCTGGCCACTGCCTGTGCCAAGCACTGCCCAGAGGCCATGATCTGTGTC
421 ATTGCGAACCCGGTCAATTCCACCATCCCCATTACTTCGGAGGTCTTTAAGAAGCACGGG
481 GTGTACAACCCCAACAGAATCTTTGGGGTCACGACGCTGGACATTGTCCGAGCAAATACT
541 TTTGTGGCACAACTGAAGGGCCTGGATCCAGCTCGAGTTAATGTCCCAGTGATCGGCGGC
601 CATGCAGGGAAGACCATCATCCCCTTGATCTCTCAGTGTACGCCCAAAGTGGAGTTCCCT
661 CAGGACCAGCTGACAGCCCTCACGGGACGGATCCAGGAGGCTGGCACAGAAGTGGTCAAG
721 GCCAAAGCTGGCGCAGGATCCGCCACCCTCTCCATGGCCTACGCCGGAGCCCGCTTCGTT
781 TTCTCCGTCCTGGACGCCATGAACGGGAAGGAAGGAGTCATCGAGTGCTCTTTTGTCCGG
841 TCCGAGGAAACGGAGTGCGCCTATTTCTCCACGCCGCTGCTGCTCGGGAAAAACGGCATT
901 GAGAAGAACCTGGGCATCGGCAAGATCTCTCCCTTCGAAGAGAAGATGGTTGCGGAGGCC
961 ATTTCGGAGCTGAAGGCGTCCATCAAGAAGGGTGAAGACTTTGCCAAGAGCATGAAGTGA
| Predicted Protein Product |
MYSRLSLQAAALTLRRGFTSSSQSNAKVAVLGASGGIGQPLSLLLKNSPLVSHLSLYDIA
HTPGVAADLSHIETRAEVKGFLGPEQLPESLKGCEVVVIPAGVPRKPGMTRDDLFNTNAT
IVANLATACAKHCPEAMICVIANPVNSTIPITSEVFKKHGVYNPNRIFGVTTLDIVRANT
FVAQLKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPQDQLTALTGRIQEAGTEVVK
AKAGAGSATLSMAYAGARFVFSVLDAMNGKEGVIECSFVRSEETECAYFSTPLLLGKNGI
EKNLGIGKISPFEEKMVAEAISELKASIKKGEDFAKSMK
| Protein Alignment to Mouse |
sp|P08249|MDHM_MOUSE Malate dehydrogenase, mitochondrial OS=Mus musculus
GN=Mdh2 PE=1 SV=3
MGI:97050 Mdh2 malate dehydrogenase 2, NAD (mitochondrial) (Chr 5)
Length = 338
Score = 1525 (541.9 bits), Expect = 3.8e-157, P = 3.8e-157
Identities = 294/339 (86%), Positives = 319/339 (94%)
Query: 1 MYSRLSLQAAALTLRRGFTSSSQSNAKVAVLGASGGIGQPLSLLLKNSPLVSHLSLYDIA 60
M S L+ A A LRR F++S+Q+NAKVAVLGASGGIGQPLSLLLKNSPLVS L+LYDIA
Sbjct: 1 MLSALARPAGA-ALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIA 59
Query: 61 HTPGVAADLSHIETRAEVKGFLGPEQLPESLKGCEVVVIPAGVPRKPGMTRDDLFNTNAT 120
HTPGVAADLSHIETRA VKG+LGPEQLP+ LKGC+VVVIPAGVPRKPGMTRDDLFNTNAT
Sbjct: 60 HTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNAT 119
Query: 121 IVANLATACAKHCPEAMICVIANPVNSTIPITSEVFKKHGVYNPNRIFGVTTLDIVRANT 180
IVA L ACA+HCPEAM+C+IANPVNSTIPIT+EVFKKHGVYNPN+IFGVTTLDIVRANT
Sbjct: 120 IVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANT 179
Query: 181 FVAQLKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPQDQLTALTGRIQEAGTEVVK 240
FVA+LKGLDPARVNVPVIGGHAGKTIIPLISQCTPKV+FPQDQL LTGRIQEAGTEVVK
Sbjct: 180 FVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVK 239
Query: 241 AKAGAGSATLSMAYAGARFVFSVLDAMNGKEGVIECSFVRSEETECAYFSTPLLLGKNGI 300
AKAGAGSATLSMAYAGARFVFS++DAMNGKEGV+ECSFV+S+ETEC YFSTPLLLGK G+
Sbjct: 240 AKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVQSKETECTYFSTPLLLGKKGL 299
Query: 301 EKNLGIGKISPFEEKMVAEAISELKASIKKGEDFAKSMK 339
EKNLGIGKI+PFEEKM+AEAI ELKASIKKGEDF K+MK
Sbjct: 300 EKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK 338
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