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Gene Model: Dlst

NomenclatureGenomic Location
SymbolDlstChromosome2
NameDihydrolipoamide S-succinyltransferaseLinkage mapunknown
SpeciesDracomimus familiarisGenome Coordinates2: 8 Mbp

Molecular Function

Molecular Function Terms:

binding
   protein binding
      chaperone binding

catalytic activity
   transferase activity
      transferase activity, transferring acyl groups
         transferase activity, transferring acyl groups other than amino-acyl groups
            S-acyltransferase activity

Human Disease Association

No disease association.

Predicted Transcript
     1 TCTCTGGCTCGGGCTCGTTGCTTCAGCCGGCTGCTGGGCCGCTCGCTCTGCGCTCCGCGA
    61 CAGGGAAACTGTCCACAGGGAAAACGTTCACTCTCTGGTGTCTCTCGATGCCAGGGGCTG
   121 GCTTATGCCAACAGTAGGAAGCATTTGGTAAATAGCTCCCGTGTGTTCACTGTCCGTTAT
   181 TTCAGAAGCACCGCAGCATGTCGGGAGGAAGTTGTTACAGTGAACACACCGGCGTTTGCA
   241 GAATCAGTCACAGAGGGAGATGTCAGGTGGGAGAAAGCTGTGGGAGACACAGTAGCAGAA
   301 GATGAAGTGGTGTGTGAGATTGAAACAGACAAGACATCTGTGCAGGTTCCAGCTCCAGCA
   361 GCTGGTGTAATTGAAGCACTTCTTGTCCCTGATGGAGGGAAAGTCGAAGGAGGTACACCT
   421 TTGTTTAAACTCAGGAAAGGTGGAGCTGCACCTGCCAAGGCCAAACCAGCAGCAGCCCCT
   481 GCACCAGAGCCTGCTGCAGCACCTGCACCACCAATTGCCCCTGCAGCACCAATTCCCACC
   541 GCAATGCCTCCAGTGCCCCCTGTGTCAGCAGTCCCTGTTGATGCTAAACCAGTGTCTGCA
   601 GTAAAGCCAACTGCAGCTCCAGCAGCTGCTCCTGCGGAACCTGGGGTCAGCAAAGGTGCC
   661 AGGTTGGAACAAAGGGTGAAGATGAATCGGATGCGTCAGCGCATAGCCCAGCGCCTGAAA
   721 GAAGCTCAAAATACATGTGCCATGCTGACTACATTCAATGAAATTGATATGAGTAACATC
   781 CAGGAAATGAGAGCCCGACACAGGGACAGTTTCCTAAAGAAGCACAATATGAAACTTGGA
   841 TTTATGTCTGCCTTTGTGAAAGCTTCAGCCTTTGCCCTGCAAGAGCAACCCGTTGTAAAT
   901 GCAGTGATTGATGATACAACCAAAGAGATTGTATACAGGGAATATGTGGATATCAGTGTT
   961 GCAGTTGCAACTCCAAGGGGTCTCGTAGTCCCTGTCATCAGAAATGTAGACACAATGAAT
  1021 TTTGCTGATATTGAAAGAGCAATCAATGAACTGGGAGAAAAGGCCCGCAAGAACGAGCTT
  1081 GCCATTGAAGACATGGATGGTGGTACATTCACTATCAGCAATGGTGGTGTATTCGGATCA
  1141 CTTTTTGGAACGCCCATTATCAACCCACCTCAGTCTGCTATTCTGGGGATGCACGGCATC
  1201 TTTGACAGGCCTGTTGCTATTGGAGGCAAGGTTGAGGTGCGACCAATGATGTTTGTGGCC
  1261 CTGACATATGACCACCGTTTGATTGATGGCAGAGAGGCAGTGACTTTCCTGCGTAAGATC
  1321 AAGGCCGTGGTGGAAGACCCTCGTGTGCTGTTGCTTGACCTGTAA

Predicted Protein Product
SLARARCFSRLLGRSLCAPRQGNCPQGKRSLSGVSRCQGLAYANSRKHLVNSSRVFTVRY
FRSTAACREEVVTVNTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPAPA
AGVIEALLVPDGGKVEGGTPLFKLRKGGAAPAKAKPAAAPAPEPAAAPAPPIAPAAPIPT
AMPPVPPVSAVPVDAKPVSAVKPTAAPAAAPAEPGVSKGARLEQRVKMNRMRQRIAQRLK
EAQNTCAMLTTFNEIDMSNIQEMRARHRDSFLKKHNMKLGFMSAFVKASAFALQEQPVVN
AVIDDTTKEIVYREYVDISVAVATPRGLVVPVIRNVDTMNFADIERAINELGEKARKNEL
AIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMFVA
LTYDHRLIDGREAVTFLRKIKAVVEDPRVLLLDL
Protein Alignment to Mouse
sp|Q9D2G2|ODO2_MOUSE Dihydrolipoyllysine-residue succinyltransferase component
            of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Mus
            musculus GN=Dlst PE=1 SV=1
      MGI:1926170 Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Chr 12)
        Length = 454

 Score = 1131 (403.2 bits), Expect = 3.3e-172, Sum P(2) = 3.3e-172
 Identities = 219/240 (91%), Positives = 231/240 (96%)

Query:   215 GVSKGARLEQRVKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHRDSFLKK 274
             G +KG R E R KMNRMRQRIAQRLKEAQNTCAMLTTFNE+DMSNIQEMRARH+D+FLKK
Sbjct:   215 GAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKK 274

Query:   275 HNMKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEIVYREYVDISVAVATPRGLVVPVIR 334
             HN+KLGFMSAFVKASAFALQEQPVVNAVIDD TKE+VYR+Y+DISVAVATPRGLVVPVIR
Sbjct:   275 HNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIR 334

Query:   335 NVDTMNFADIERAINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAI 394
             NV+TMN+ADIER INELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAI
Sbjct:   335 NVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAI 394

Query:   395 LGMHGIFDRPVAIGGKVEVRPMMFVALTYDHRLIDGREAVTFLRKIKAVVEDPRVLLLDL 454
             LGMH IFDRPVA+GGKVEVRPMM+VALTYDHRLIDGREAVTFLRKIKA VEDPRVLLLDL
Sbjct:   395 LGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL 454

 Score = 558 (201.5 bits), Expect = 3.3e-172, Sum P(2) = 3.3e-172
 Identities = 106/147 (72%), Positives = 124/147 (84%)

Query:     2 LARARCFSRLLGRSLCAPRQGNCPQGKRSLSGVSRCQGLAYANSRKHLVNSSRVFTVRYF 61
             L+R+RC SR   RSL A ++GNCP G+RSL GVS C+G  Y ++RK ++NS  VF VR+F
Sbjct:     2 LSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCRGPGYPDNRKMVINSGSVFRVRFF 61

Query:    62 RSTAACREEVVTVNTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPAPAA 121
             ++TA C+ +V+TV TPAFAESVTEGDVRWEKAVGD VAEDEVVCEIETDKTSVQVP+PA 
Sbjct:    62 QTTAVCKNDVITVQTPAFAESVTEGDVRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPAN 121

Query:   122 GVIEALLVPDGGKVEGGTPLFKLRKGG 148
             G+IEALLVPDGGKVEGGTPLF LRK G
Sbjct:   122 GIIEALLVPDGGKVEGGTPLFTLRKTG 148