| Nomenclature | Genomic Location |
| Symbol | Lama3 | Chromosome | 1 |
| Name | Laminin, alpha 3 | Linkage map | unknown |
| Species | Dracomimus familiaris | Genome Coordinates | 1: 58 Mbp |
| Molecular Function |
|
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment,
migration and organization of cells into tissues during embryonic development by interacting with
other extracellular matrix components.
Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal
adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine
phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Molecular Function Terms:
(none)
|
| Human Disease Association |
|
Defects in LAMA3 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB) [MIM:226700];
also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering
skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement
membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six
months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth
and extensive denudation of skin and mucous membranes that may be hemorrhagic.
Defects in LAMA3 are the cause of laryngoonychocutaneous syndrome (LOCS) [MIM:245660]. LOCS is an
autosomal recessive epithelial disorder confined to the Punjabi Muslim population. The condition is
characterized by cutaneous erosions, nail dystrophy and exuberant vascular granulation tissue in
certain epithelia, especially conjunctiva and larynx.
|
1 ATGGCAGCGGAGGGAAGGAGAGGAGGAGGAGGAAGAGGGGCCCCTTTGGCAGCCCTGGCT
61 GGGCTTCTCTTTCCCCTTTGGCCCGGCTTCCTCGTCCCCTCCGTGGGCGCCCAGCAGGCT
121 CCTTCCCTGGACTTTGGACCGGGCACCAGCAGCAGCCTCCAGCCGCCTTACTTCAACCTG
181 GCCGAGACGGCGGGCATTTGGGCCACAGCCACCTGCGGGCAGGACGAGGGGGGGAAGCCC
241 CGCGCGGAGCTCTATTGCAAGCTGGTGGGGGGGCCCGCCGCTTTCCCCGCCGGAAAGACC
301 ATCCAGGGCCAGTTCTGTGATTATTGTAATGCTGCTGATCCAAAGAAAGCTCACCCAGTA
361 ACCAATGCTATAGATGGGACCGAGCGCTGGTGGCAAAGTCCGTCTCTCTCCTTAGGTCTG
421 AAGTATGATGAAGTCAATGTTACTTTAGATCTAGGACAGCTCTTTCATGTGGCGTATGTC
481 CTCATCAAATTTGCCAATTCACCTCGTCCAGATTTGTGGGTATTAGAAAGATCTGTAGAT
541 TTTGGAAGAACCTACAAACCATGGCAATATTTTGCTCATTCTAAGCTAGATTGTTGGCAA
601 CATTTCGGAAAGGAGGCAAATGTTCGTGTTAAAGAAGATGATGATGTTATTTGTACCATA
661 GAATATTCTAGGATTGTGCCTTTAGAAAATGGAGAGGTTGTGATATCCTTGGTAAATGGC
721 CGCCCAGGAGCGAATAACTTCACCCATTCCCCCACACTTAGAGAATTTACTAAAGCAACG
781 AATATCCGTTTGCATTTCCTCAGAACCAACACACTTCTTGGGCACTTGATATCTAAAGCG
841 CAACGAGATCCCACCGTGACACGCAGATACTTCTACAGTATAAAAGATATCAGTGTGGGT
901 GGGCAATGTGTTTGCCATGGACATGCCGAGGTCTGTGATCCAAAAAAGGACCCAGATTCA
961 TACAGGTACCAGTGTGAATGTCAGCACAACACATGTGGAGAAACATGTGATCGTTGCTGC
1021 CCTGGATATCATCAAAAACATTGGCAGCCAGCAACTACCAGCAGCTCAAACCTCTGTGAA
1081 CCATGCAACTGCCATGGACATGCCACTGACTGCTATTATGACCCTGAGATTGAGCAGCGT
1141 AAAGCAAGCTTAAATATCTATGGGGAATATCAAGGTGGCGGGGTCTGCATTGACTGTCAG
1201 CATAACACGGCTGGTGTAAATTGTGAGAGGTGCGTGAAGGGTTACTATCGTCCTTATGGT
1261 GTTCCGGTGACAGCGGCACATGGATGTATCCCCTGCAACTGCAGTCCAGAGCATTCTGAT
1321 GGCTGTGAAGAAGGATCAGGCAGATGTTATTGCAAACTGAATTATCAGGGTGAAAACTGT
1381 GATGAGTGTGCTGATGGATATCATAGTTTCCCCTTCTGTTACTGGATTCCTGTTTATCCT
1441 GTAATTACTCCAGCTCCAAAAGAGGATCCTTCAGCTGGTCATATAATTGCAAAGTGTGAA
1501 TGCAATTTAGCTGGCACTCTCCCAGAAATGTATGACTTCCAAGGGAGATGCCTTTGTCGT
1561 TCTGAGGTAAATTATGCTGGGCCTAAATGCAGCCAGTGTGCCGCTGGATATTACAGCTAT
1621 CCCAGTTGCTTCCCTTGTAGGTGCTCACCTCAAGGATCCAACCAAGAGTCGTGTGACCCA
1681 GCCACAGGGCAGTGTGAATGCCGACCTGGTGTATCAGGGCAGCAGTGTGACAGATGCCTC
1741 TCAGCAGATAAGCACTTTCCTTATTGTCATCAACCAAAAGGAACAAACCATGAATGTGAC
1801 CCAGCTGGAGCCGTCGATTCATATTCTGACTATTGTCAGTGTCTGCAGAATGTGGAAGGC
1861 CCCACATGTAGCATCTGCAAACCAATCTACTGGAACCTGGCCAGAGAAAACCCTGAGGGA
1921 TGTGTAGAATGTCAGTGCAATGCATCTGGAACACTGAGCGGAGTCAGAGAGTGTCAGCAG
1981 GTTGATGGCGAATGTTATTGTAAACCTAACGTTTGTGGAGATTCTTGTGATATGTGTGAA
2041 GATGGTTATTATGGGTTAGAGGCCAAGAACTACTTTGGATGTCAAGGATGTGAATGTGAT
2101 GTGGGAGGGTCTGTAAGCCAGGTGTGTGATGATCTGTCTGGTGACTGTCAGTGCAGAAAC
2161 CACATGGTTGGGAAAAACTGCAATGAGCCAAAAAAGAACTACTATTTGCCTGATTTACAT
2221 CACATGAAATATGAAATTGAAGATGGAACATCTCCTAATGGAAGAGGGATCCGGTTTGGT
2281 TATGACCCTCAAGAATTTCCCAGCTTTAGTTGGAGAGGTTATGCACAGATGTCCTCAATA
2341 CAAAATGAAGTGAGGATAACTCTGAATGTGAACAAACAAAATCTCTCTTTATTTCGTGTT
2401 ATCTTGAGATATATTAATCCCGGAACATCTGTAATATCTGGCCATATAACTGCGCATCAA
2461 ACTCGTCCTCGGAACGGAACTCATCAGAGGAAAGACATTGTGTTCCCACCAAGTCGTGAG
2521 CCCTCTTTTGTCACTGTCCCAGGGAGGAACCCCGCAGACCCATTTTTGCTGGGTCCTGGA
2581 ACATGGATTCTTAAAATCATGGCTGAGGGAGTCCTTCTGGATTATTTGGTGCTCTTACCA
2641 CGTGACTATTTTGAGGCACCCATCCTGCAGTTACCTGTTAGAGAACCTTGCACATATTCA
2701 AGACATGCCACAACAGATAACTGTTTGCAATATGAGCACTTGCCATTGGAAAGATTTTCG
2761 TGTGTATTTGGCTCCGAAGTAACATTTTTCTTGCAAGGAGGAGAATACAGGAAAGTTGTT
2821 TTCCAACAGCCAAGTGCCAAACATCCACTTATGTCTTACATAAGTGGTCAAGAGGTGGAT
2881 CTTCAAATCAGATTAAATGTTCCCCAAGTGGGCCGCTACGTAATAGTACTTGAGTACGTC
2941 AATGAACACAATAAAATGTATGTTGGTAATGTGGAGATCAAAAGCCTGGGACACATGTCA
3001 GAGGCAAAAATTAATCTATACAATTGCAAGTATAGCTTCCTATGTCGCAGTGTTGTGACT
3061 GATGATCTGAATCGCATTGCAGTTTATGACCTTTTGTCTGATGCAGAGTTCCGTCTCAGG
3121 TTGCCAGAAATACATTTTCTTCTGAATAAAATTTGCATTATTCCAGTGGAAGATTTTTCC
3181 CTAGAATATGTGAAGCCTCAGCTGCATTGCATTGCCACATATGGCCAATCATCAAGTTCA
3241 AGTGCTTCATGCATCCCTTCACAGTATGAAACGCCTCCTTTAACAGTGGTGTTGGATGCT
3301 CTGAGAAATAAAGGCTATCAAGATTCACTGAGGGCTCCCTTTCCAAATGCACACACAGCT
3361 AATGGAGTGACTTTGACATCTTCACAGAACCAAATTACTCTGAGAGGGAGAGTGATACAT
3421 TTGGGCAGATATGTGTTCATCATACATTTTTATCAGCCAGAGAGCCCAATGTTTCCAGTG
3481 GAAGTAACTATAGATGGAGGACAATTCTGGTCAGGTTCTTCTAATGCTTCATTTTGTCCA
3541 CATATTTCTGGATGTCGAGGCCTGGTGATGGCAGAAAGCCAAATTGAACTTGACATCTTC
3601 AAACATGATATCTTGGTCACTGTGAAAATTCCTAATGGAAAAAAAATGGTGTTGGGCCAC
3661 ATTTTGGCTGTTCCTGCTGACAGTTACAGTTACACACTTCTCCATCAAGACACTGTGGAC
3721 AAGTCACTTAATTTCATCTATCAGTGTGGTGAAAACAGTTTTCACATTACCCCTGTAATG
3781 TCCTCAGAATTCTGCAGAAATTCAGTAAGGTCTCTTGTGGCAGCCTACAACAATGGTGCA
3841 CTGCCTTGCAATTGCCACAGAAATGGTGCCGCCAGTCCTACATGTGACCCTATGGGAGGG
3901 CAGTGCCCCTGCAAACAAAACATTATTGGCCTTCAGTGCAATAGGTGCCGAACAGGCTAT
3961 TATGGATTTCCATTTTGCAAACCATGCCGTTGTGGGTGGCGCCTTTGTGATGATATCACT
4021 GGCAAGTGTATTTGTCCTCCTCAAACCGTAAAGCCAAGATGTGAAGTGTGTGTGAGGCAG
4081 CACTTTGGTTACCACCCGCTTGTTGGATGCGTGGGATGCAATTGCTCAAGTCAAGGGGTT
4141 GTTAATGCAGTGAACCCTGAATGTGATAAAAAGAACGGGCAGTGCAGATGCCGCTCAGGA
4201 ATAACAGGCCGACGATGTGATCAGTGCGCTCCTGGTTCCTTTGGTTTTCCAAACTGCAAG
4261 CCCTGCAATTGTAATAGAGGAGGAACAGAACCAAATGTTTGTGATCCACAAACAGGAGTT
4321 TGCCTCTGTAAGGAGAATGTTGAAGGTATTCAGTGTGACATGTGCCGCTCTGGATCATTT
4381 TACTTGGACTCCACTAATCCAAAGGGTTGCACCAATTGCTTTTGTTTCGGAGCAACCGAT
4441 ATTTGTCATAGTACGAATAAAGATAGAATCAAGTTTGTTGAGATGCGGAACTGGCGCCTG
4501 AAAGATGTGGATAACAGTATGAACATCCCAGTCATTTTTAATCCCGGCAGCAACAGTGTT
4561 GTTGCTGATGTCCAAGAGCTCCTTCCCTCTGTGTGCAATTTGTATTGGGTGGCACCTCCA
4621 TCTTACTTGGGAGATAAGCTTTCTTCATATGGGGGCTACTTAATGTATCAGGTTAAAACC
4681 TTTGGATTACCCAGTGAAGGCATGACTTTACTGCAAAAAAGGCCTGATGTGCAGCTGACT
4741 GGGCAACAGATGAAGCTAATCTATGTGGATCCTAACAACCCTTTGCCTGACAAACAGTAT
4801 TATGGTTCTGTTAAACTAGTTGAGGGGAACTTCAGACATGCAAGCAGCAATGACTTGGTA
4861 ACACGGGAGGAGCTGATGATGGTCCTGTCTAGACTAGAAGGATTACAAATCAGAGGACTT
4921 TATTTCACAGAATCTCAGCGGTTAACCTTGGGCGAGGTTGGGCTGGAAGAAGCCACGGGT
4981 ACAGGAAGTGGCAATGCTGCTTATAATGTAGAGACATGCTCCTGCCCCGCTGGATATCTG
5041 GGTGATTCATGCCAGGAGTGCAGCCCTGGATTTTATCGTGAGAACAGAGATCGGCTGACA
5101 GGACGGTGTATTCCTTGCAATTGTAATGGAAATTCAGATAGATGCCTCGATGGTTCTGGA
5161 ATTTGTCTTAACTGTCAGCATAATACTGCTGGTGACAACTGTGAGTATTGCAGAGAAGGT
5221 TACTTCGGTGATGCCAGTCAAGGAAACTGCAGGGCATGTCGCTGCCCTTATACAAACAGT
5281 TTTGCCTCCGGCTGCATAGAAAATGATGGAGATATTCAATGCTTCTGCAGAGAAGGCTAT
5341 ACTGGAGTACATTGTGAAAGCTGTGCTCCTGGTTATTTTGGTAACCCACTGAAATATGGA
5401 GGATTTTGTCAGAAATGTAATTGCCCTAACAATGGCCAGCTACCGAACTGCGATCGTCTG
5461 ACTGGAGAATGTATAAATCAAGAACCAAAAGACATAGATCCTCATGAAGACTGTGATGCT
5521 TGTGATAGCTGTGTGATTACTCTGCTAAAAGATCTGAGTTCAATGCAAGATGAACTCCAA
5581 GTGATTAAGTTCCAGATGCAAAATGTCAATGCCAGTACCCACACACTGGGGCAGATGAAG
5641 CATCTGGAAGACCGGGTCAAACAGCTGAAGAGTCTGTTGAGCCGCTATCGTTCCGTTATT
5701 ACCACTCAGGGCTCCAAAGTGGATGAACTGGATACAGATTTCATTGCCCTTAATCAGAAT
5761 GTTAATGCTCTAAGAGAAAAGGCTGAAAATAATTACAAGAAAGCAGAGACACTGTTCAAT
5821 AATTTTGGTAAGACTAACCAGAGAGGAAAGGATTTGATTTCAAAGATACAGAGTCTTGTC
5881 ATCAATATTAATGTCCTCCTGAATCAGGTACCTGGGACTTCTGGGGAAGGAACTTCTTTG
5941 CCTTCAGGAAATGCTGCTGAAGAGCTGGCTAAAGCTCGGCAAATGGTGAACGAGATGAGA
6001 GACCGCAATTTTGGCCTGCAGCTGAGAGAAGCAGAAAAAGAGAACGGAAAAGCTCAGAAT
6061 TTGCTGGATCGTGTAAAGAATGAACTACAGAAGCACCAAGCAGAAAACCAAGGTCTTATT
6121 AAAATTGTAAGAGATTCATTAAATGAATATGAATTGAAACTGAATGACCTTCGTGAATCT
6181 TTGAAAGAAGCAAAAGAACAAACAAAGTTGGCTGAAACTTTAAATGTAGATAATAAAATC
6241 CTCTTTGAAGATATCAAGAAACGGACTGAGGAGATGTCTAAACAACAGAACGAGATCTTG
6301 GATGTTCTGGATTCTGCTGAAGCATCATTGTCTAAAGCAAATAGTGCATTTGTATTGCTG
6361 CAGAGGAGTAAAGAGGAATATGAAACTTTAGCTGCCCAACTGGATGGTGCAAGGAAAGAG
6421 CTCACTGAAAAACTGAAGAGTCACTCTTTAGCAGCCAGCAAAGAACCTCTGGTAGTCAGA
6481 GCAGAAGAACATGCCATCTCTTTACAGGAGCTAGCAAAAAAGTTGGATGAGATCAAAAGA
6541 AATGCCAGTAATGATGAGCTGGTAGCCTGTGCCATGAAAGCTGCAAGTGCCTATGAGGAC
6601 ATTATTAATGCCATCAAAGCAGCAGAGACCGCGGCCAACAGAGCTGCAGATGCTGCCAAT
6661 TCAGCTGTATCAACAATGGAGAAGAAAGATCTAGCGGGAAGGGCCAACAGACTGAAGACC
6721 AGCAGTGGCAATCTACTAAATCAAGCCCAGGCAGCACAAAAGACACTACAGGAAATCAGT
6781 CCAACTCTTGACAATGTAAAGAGTCGACTTCAAGATGCTGAGCGTAAGAAGAATATGATT
6841 CAAGGAGATCTCACAGACTTCCAAAATCAACTACAAGGGATGAAGAGAGATGACATAGAA
6901 AGCATGATCATGAATGCAAAGAACATGGTCAAAAATGCCAACGATATTACTACTAATGTA
6961 CTTGATGAATTGGACCCAATTAAAACAGATGTTGAAAACATAAAAAACACCTATGGAACC
7021 ATGCAGAGTGCTGACTTCGACAATGCTCTGAAAAAAGCAAACAATACAGTAAACAACTTG
7081 ACAAATATCCTACCTGATCTATTTAACAAGATCACCAGCATCAACCAACAACTTATGCCA
7141 ATAAGCAACATATCTGAAAATATAAATCGTATCAGAGAGCTCATCCAGCAAGCAAGAGAT
7201 GCTGCAAACAAGGTTGCTATTCCCATGAGGTTTGATGGCAGTTCCGGGGTAGAGGTTCGA
7261 CCTCCAGACATTCTTGAAGATCTGAAAGGCTATACGTCCCTGTCCTTATTTCTTCAAAGA
7321 CCTCTCTCACGATTGGACAGTCCACAGCAGACATCTGACATGTTTGTCATGTACTTAGGT
7381 GACAAAGATAGTTCCAAAGACTACATCGGCATGGCTGTTCGGGGTGGCCGTCTTATTTGT
7441 GCCTACAGCTTAGGAGGCAATGAAGCTGAAATAGAAGTTCTTGAAACGGTGTCCGATAGT
7501 GACACCAGGGAAGCGACTATGGATCTTGTGAAATTTGAGAGAATTTACCAATATGCAAAG
7561 CTGAACTACATTAAGGGTGCAACCTCCTCTTCACCATTAAGTCTAGGACCTTATGAGGAC
7621 AGCAGTGGGGATCAGTATACCCTCCTCGACTTGAATCCTGACAATGTGGTCTTCTATGTT
7681 GGAGGATACCCACCAGATTTTACACCCCCTGATACACTGAATCATCCTCGGTATGAAGGC
7741 TGCATTGAATTTGACAGTTTAAATGAGAGAGTTCTAAGCCTGTACAATTTCAAGAGGACT
7801 TTTAATCTCAACACTACTTTAGTACAACCATGCAGAAGATACAAAGAACAGTCTGCCAAA
7861 ATCTATTTTGAAGGCACAGGTTATGCACGTGTTAATGCTGCTCCTCCAAGTGTCTCTCAC
7921 ATACGGTATGAACAAACTATTCAGACTACTGCAGATGAAGGACTGGTATTTTTTGCTGAA
7981 AATCAGGACAAATTCATCAGTTTGAGGATTGAAGAAGGTCATCTAATATTCAGATACAAA
8041 ATAGATTCACAGCCCCCAAAAGAGAAAGAGAGCTCATTGATCATCAACAATGGAATGGAT
8101 CAAGTGGTAAGTGTCTCCCCAACTACCATAACCCAAAAGCAGTTTACTCTGATTGATAAA
8161 TCTACAGTACAAGCAAAGGCAACTACATTTCGGTTTGATTCATATTACTTGGGTGGAGCT
8221 CCAAACTCTTTAAGAGAACGCTTTAATATAACCACACCTCCATTTCGTGGATGCATGATG
8281 AATGTGAGAACTTCATTTGAGTCTTCCATTAGCTTCTCTGAGACTCTTGGTGTCAGCAGA
8341 AAATGCCCTGATGATTGGAAGATTGTGAGAGTTGCAAGTTTTTCCAAGAATGGAGTACTT
8401 GGTTTGAGTGATGAAGGCTTTCAATTTCCGAATGATTTCCAAGTTGGTTTTGGCTTTCAC
8461 ACACTGGCGCTTGATGGAACCTTGTTGAATTACAATTTACGGTCTGATATATTTAGTGTT
8521 ATCCTGAGAAATGGCTCTGTAATTGTAAGGATAGCTGATGAAGAAATCCAGTCTAGCAAA
8581 GGATATGGAGATGGTGTAATTCACTATGTAACAGTGATGAAAGAAGACGACACGCTTAGA
8641 GTGATTATTGATGATGCCTCTGAATTAACAATGTTTCCTCCAGCTGGAAGGAAAATGCTC
8701 AGTCATCCAATAGACCTTGGTGGTAATAATTTTGAAGGTTGCATTTTCAATGTCTTTATA
8761 CAAAGAAAAGGACAATTTCCTCACGTACAAAGTCTAACCAATTATGATAGGAAAACTGAT
8821 GTGTCTTTAGGATTCTGTATGATAAGAAGACAACCACAGCCAATGCTACTGCGAGAATTA
8881 GCAGGGAAGGATAAACATGCAGTAAAGAGAAGTTGGATGATCTTAGTGCCAGATAAACTG
8941 AAGATTGGAACTAAATTCCCTAAAGACACCACTTCCCATCTGATAAGGGTGAGCTCTATC
9001 ACTGGAGCTTATCACTTTGGCAATACCCCTGACACTTATTTGTTATTTACGTCTTCTCAA
9061 ATGTCATCAAGAGGCCGGCACCTAAGGTCACACTTTGCAGTTGATGTTCGTACAACATCA
9121 TCTAGAGGTCTGATCTTCTTCATGGGAGAGAAGCTGGAGAACAGATATATAACTCTTTAC
9181 CTTTCAAAGGGACGTTTTGTCTTTCTGCTTGCTGCTGATGGAAGAAAAATAAAGATCAAG
9241 AGCAAAGCCAAATACAGTGATGGACAATGGCATACAGTGGCGTTCAGCCAGACTGGAGAG
9301 AAGATGCGCCTCATAGTTGATGGCCTGAATGCTCGACAGGGGAATATACCGCCTACTTTC
9361 TCTATCAGGACTGAGTCTCCAATCTACCTAGGAGGAGTTCCTTCATTAAAGATTCAGAAT
9421 ATACCAAAAAAGAGCTTTGTAGGATGCTTAAGAGCTTTTAACGTGGGAGGAAAGCCTGTA
9481 CACACTTACCATCAGAACAGTGGTGTCTTGCCTTGTCTGGATAACACTTTGGAGAAGGGG
9541 ATTGCCTTCTTCAATGAAGGGGGACATGTTGTCATTGAAAGAACTTTCTTGATGAACTTG
9601 GACTATAAGATTGCTTTTAGCATTCGCCCAAGAAGCTCCACTAGCCTGTTAATCCATATT
9661 GGCACCAAGCAAGAAAACTATTTTGCTGTTTACATGGACAAAGGTGTGGTCACTGCCTCT
9721 GGAAATAATGGTGCTGGAGAATTCTTGACGTCACTCACACCTCAGCAATCTCTTTGTGAT
9781 GGAAAATGGCACTCCATAGCAGTAACTCAGAAGAAGAACACAGTGCACCTTGATGTGGAT
9841 ACAATGAGTAATTACACTACTGGACCATCAACTGTACTTTCCACCAGCCATGCTCAACCA
9901 CTTTACTTTGGGAGAGTTCCAGCAAACCTGGAAATGCCATGGCTTCCTGTTCAGGACATG
9961 TTTCTTGGCTGTCTGAAGGATGTTAAAATCAATGACAAACCGGTCTTAATACGCAAAAAT
10021 GCAGACATCCATGGTGGTGTCAGTTTGCAAGGGTGCCCTGTTAATTAA
| Predicted Protein Product |
MAAEGRRGGGGRGAPLAALAGLLFPLWPGFLVPSVGAQQAPSLDFGPGTSSSLQPPYFNL
AETAGIWATATCGQDEGGKPRAELYCKLVGGPAAFPAGKTIQGQFCDYCNAADPKKAHPV
TNAIDGTERWWQSPSLSLGLKYDEVNVTLDLGQLFHVAYVLIKFANSPRPDLWVLERSVD
FGRTYKPWQYFAHSKLDCWQHFGKEANVRVKEDDDVICTIEYSRIVPLENGEVVISLVNG
RPGANNFTHSPTLREFTKATNIRLHFLRTNTLLGHLISKAQRDPTVTRRYFYSIKDISVG
GQCVCHGHAEVCDPKKDPDSYRYQCECQHNTCGETCDRCCPGYHQKHWQPATTSSSNLCE
PCNCHGHATDCYYDPEIEQRKASLNIYGEYQGGGVCIDCQHNTAGVNCERCVKGYYRPYG
VPVTAAHGCIPCNCSPEHSDGCEEGSGRCYCKLNYQGENCDECADGYHSFPFCYWIPVYP
VITPAPKEDPSAGHIIAKCECNLAGTLPEMYDFQGRCLCRSEVNYAGPKCSQCAAGYYSY
PSCFPCRCSPQGSNQESCDPATGQCECRPGVSGQQCDRCLSADKHFPYCHQPKGTNHECD
PAGAVDSYSDYCQCLQNVEGPTCSICKPIYWNLARENPEGCVECQCNASGTLSGVRECQQ
VDGECYCKPNVCGDSCDMCEDGYYGLEAKNYFGCQGCECDVGGSVSQVCDDLSGDCQCRN
HMVGKNCNEPKKNYYLPDLHHMKYEIEDGTSPNGRGIRFGYDPQEFPSFSWRGYAQMSSI
QNEVRITLNVNKQNLSLFRVILRYINPGTSVISGHITAHQTRPRNGTHQRKDIVFPPSRE
PSFVTVPGRNPADPFLLGPGTWILKIMAEGVLLDYLVLLPRDYFEAPILQLPVREPCTYS
RHATTDNCLQYEHLPLERFSCVFGSEVTFFLQGGEYRKVVFQQPSAKHPLMSYISGQEVD
LQIRLNVPQVGRYVIVLEYVNEHNKMYVGNVEIKSLGHMSEAKINLYNCKYSFLCRSVVT
DDLNRIAVYDLLSDAEFRLRLPEIHFLLNKICIIPVEDFSLEYVKPQLHCIATYGQSSSS
SASCIPSQYETPPLTVVLDALRNKGYQDSLRAPFPNAHTANGVTLTSSQNQITLRGRVIH
LGRYVFIIHFYQPESPMFPVEVTIDGGQFWSGSSNASFCPHISGCRGLVMAESQIELDIF
KHDILVTVKIPNGKKMVLGHILAVPADSYSYTLLHQDTVDKSLNFIYQCGENSFHITPVM
SSEFCRNSVRSLVAAYNNGALPCNCHRNGAASPTCDPMGGQCPCKQNIIGLQCNRCRTGY
YGFPFCKPCRCGWRLCDDITGKCICPPQTVKPRCEVCVRQHFGYHPLVGCVGCNCSSQGV
VNAVNPECDKKNGQCRCRSGITGRRCDQCAPGSFGFPNCKPCNCNRGGTEPNVCDPQTGV
CLCKENVEGIQCDMCRSGSFYLDSTNPKGCTNCFCFGATDICHSTNKDRIKFVEMRNWRL
KDVDNSMNIPVIFNPGSNSVVADVQELLPSVCNLYWVAPPSYLGDKLSSYGGYLMYQVKT
FGLPSEGMTLLQKRPDVQLTGQQMKLIYVDPNNPLPDKQYYGSVKLVEGNFRHASSNDLV
TREELMMVLSRLEGLQIRGLYFTESQRLTLGEVGLEEATGTGSGNAAYNVETCSCPAGYL
GDSCQECSPGFYRENRDRLTGRCIPCNCNGNSDRCLDGSGICLNCQHNTAGDNCEYCREG
YFGDASQGNCRACRCPYTNSFASGCIENDGDIQCFCREGYTGVHCESCAPGYFGNPLKYG
GFCQKCNCPNNGQLPNCDRLTGECINQEPKDIDPHEDCDACDSCVITLLKDLSSMQDELQ
VIKFQMQNVNASTHTLGQMKHLEDRVKQLKSLLSRYRSVITTQGSKVDELDTDFIALNQN
VNALREKAENNYKKAETLFNNFGKTNQRGKDLISKIQSLVININVLLNQVPGTSGEGTSL
PSGNAAEELAKARQMVNEMRDRNFGLQLREAEKENGKAQNLLDRVKNELQKHQAENQGLI
KIVRDSLNEYELKLNDLRESLKEAKEQTKLAETLNVDNKILFEDIKKRTEEMSKQQNEIL
DVLDSAEASLSKANSAFVLLQRSKEEYETLAAQLDGARKELTEKLKSHSLAASKEPLVVR
AEEHAISLQELAKKLDEIKRNASNDELVACAMKAASAYEDIINAIKAAETAANRAADAAN
SAVSTMEKKDLAGRANRLKTSSGNLLNQAQAAQKTLQEISPTLDNVKSRLQDAERKKNMI
QGDLTDFQNQLQGMKRDDIESMIMNAKNMVKNANDITTNVLDELDPIKTDVENIKNTYGT
MQSADFDNALKKANNTVNNLTNILPDLFNKITSINQQLMPISNISENINRIRELIQQARD
AANKVAIPMRFDGSSGVEVRPPDILEDLKGYTSLSLFLQRPLSRLDSPQQTSDMFVMYLG
DKDSSKDYIGMAVRGGRLICAYSLGGNEAEIEVLETVSDSDTREATMDLVKFERIYQYAK
LNYIKGATSSSPLSLGPYEDSSGDQYTLLDLNPDNVVFYVGGYPPDFTPPDTLNHPRYEG
CIEFDSLNERVLSLYNFKRTFNLNTTLVQPCRRYKEQSAKIYFEGTGYARVNAAPPSVSH
IRYEQTIQTTADEGLVFFAENQDKFISLRIEEGHLIFRYKIDSQPPKEKESSLIINNGMD
QVVSVSPTTITQKQFTLIDKSTVQAKATTFRFDSYYLGGAPNSLRERFNITTPPFRGCMM
NVRTSFESSISFSETLGVSRKCPDDWKIVRVASFSKNGVLGLSDEGFQFPNDFQVGFGFH
TLALDGTLLNYNLRSDIFSVILRNGSVIVRIADEEIQSSKGYGDGVIHYVTVMKEDDTLR
VIIDDASELTMFPPAGRKMLSHPIDLGGNNFEGCIFNVFIQRKGQFPHVQSLTNYDRKTD
VSLGFCMIRRQPQPMLLRELAGKDKHAVKRSWMILVPDKLKIGTKFPKDTTSHLIRVSSI
TGAYHFGNTPDTYLLFTSSQMSSRGRHLRSHFAVDVRTTSSRGLIFFMGEKLENRYITLY
LSKGRFVFLLAADGRKIKIKSKAKYSDGQWHTVAFSQTGEKMRLIVDGLNARQGNIPPTF
SIRTESPIYLGGVPSLKIQNIPKKSFVGCLRAFNVGGKPVHTYHQNSGVLPCLDNTLEKG
IAFFNEGGHVVIERTFLMNLDYKIAFSIRPRSSTSLLIHIGTKQENYFAVYMDKGVVTAS
GNNGAGEFLTSLTPQQSLCDGKWHSIAVTQKKNTVHLDVDTMSNYTTGPSTVLSTSHAQP
LYFGRVPANLEMPWLPVQDMFLGCLKDVKINDKPVLIRKNADIHGGVSLQGCPVN
| Protein Alignment to Mouse |
tr|E9PUR4|E9PUR4_MOUSE Uncharacterized protein OS=Mus musculus GN=Lama3 PE=4
SV=1
MGI:1344394 Lamc3 laminin gamma 3 (Chr 2)
Length = 3330
Score = 9730 (3430.2 bits), Expect = 0., P = 0.
Identities = 1786/3318 (53%), Positives = 2360/3318 (71%)
Query: 47 PGTSSSLQPPYFNLAETAGIWATATCGQ--DEGGKPRAELYCKLVGGPAAFPAGKTIQGQ 104
P +S SL PPYFNLA+ A IWATATCG+ E +PR EL+CKLVGGPAA +G TIQGQ
Sbjct: 38 PMSSRSLHPPYFNLAQAARIWATATCGERDPEVSRPRPELFCKLVGGPAAQGSGHTIQGQ 97
Query: 105 FCDYCNAADPKKAHPVTNAIDGTERWWQSPSLSLGLKYDEVNVTLDLGQLFHVAYVLIKF 164
FCDYCN+ D +KAHP ++AIDG+ERWWQSP LS G +Y++VN+TLDLGQLFHVAY+LIKF
Sbjct: 98 FCDYCNSEDSRKAHPASHAIDGSERWWQSPPLSSGTQYNQVNLTLDLGQLFHVAYILIKF 157
Query: 165 ANSPRPDLWVLERSVDFGRTYKPWQYFAHSKLDCWQHFGKEANVRVKEDDDVICTIEYSR 224
ANSPRPDLW+LERSVDFG TY PWQYFAHS+ DC + FG+EAN+ + +DD ++C EYSR
Sbjct: 158 ANSPRPDLWILERSVDFGSTYSPWQYFAHSRRDCVEQFGQEANMAITQDDQMLCVTEYSR 217
Query: 225 IVPLENGEVVISLVNGRPGANNFTHSPTLREFTKATNIRLHFLRTNTLLGHLISKAQRDP 284
IVPLENGE+V+SL+NGRPGA F S TLREFTKATNIRL FLRTNTLLGHLISKA+RDP
Sbjct: 218 IVPLENGEIVVSLINGRPGAKKFAFSDTLREFTKATNIRLRFLRTNTLLGHLISKAERDP 277
Query: 285 TVTRRYFYSIKDISVGGQCVCHGHAEVCDPKKDPDSYRYQCECQHNTCGETCDRCCPGYH 344
TVTRRY+YSIKDISVGG+CVC+GHAE C +P+ +++CECQH+TCG+TC+RCC GY+
Sbjct: 278 TVTRRYYYSIKDISVGGRCVCNGHAEACSAD-NPEK-QFRCECQHHTCGDTCNRCCAGYN 335
Query: 345 QKHWQPATTSSSNLCEPCNCHGHATDCYYDPEIEQRKASLNIYGEYQGGGVCIDCQHNTA 404
Q+ WQPA N CE CNCHGHA DCYYDP++E ++ASLN G Y GGGVCI+CQHNTA
Sbjct: 336 QRRWQPAGQEQHNECEACNCHGHAVDCYYDPDVEHQQASLNSKGVYAGGGVCINCQHNTA 395
Query: 405 GVNCERCVKGYYRPYGVPVTAAHGCIPCNCSPEHSDGCEEGSGRCYCKLNYQGENCDECA 464
GVNCE+C KGY+RP+GVPV A HGCIPC+C PE +D C++GSG C+CK N+ G+ C+ CA
Sbjct: 396 GVNCEKCAKGYFRPHGVPVDALHGCIPCSCDPERADDCDQGSGHCHCKPNFSGDYCETCA 455
Query: 465 DGYHSFPFCYWIPVYPVITPAPKEDPSAGHIIAKCECNLAGTLPEMYDFQGRCLCRSEVN 524
DGY++FPFC IPV+P TP+P EDP AG+I C+CNL G LPE+ D +GRCLCR V
Sbjct: 456 DGYYNFPFCLRIPVFPNYTPSP-EDPVAGNIKG-CDCNLEGVLPEICDDRGRCLCRPGVE 513
Query: 525 YAGPKCSQCAAGYYSYPSCFPCRCSPQGSNQESCDPATGQCECRPGVSGQQCDRCLSADK 584
GP+C C +G YS+P C C+CS GS CDP GQC+C PG++G+QCDRCLS
Sbjct: 514 --GPQCDSCRSGSYSFPICQACQCSTIGSYPVPCDPGNGQCDCLPGITGRQCDRCLSGAY 571
Query: 585 HFPYCHQPKGTNHECDPAGAVDSYSDYCQCLQNVEGPTCSICKPIYWNLARENPEGCVEC 644
FPYC +G+ C PAG +DS YCQC Q+V PTCS+CKP+YWNLA+ENP GC EC
Sbjct: 572 DFPYC---QGSGSVCHPAGTLDSSLGYCQCKQHVASPTCSVCKPLYWNLAKENPRGCSEC 628
Query: 645 QCNASGTLSGVRECQQVDGECYCKPNVCGDSCDMCEDGYYGLEAKNYFGCQGCECDVGGS 704
QC+ +GTLSG+ EC Q DG+C CK +V GD+CD CEDG++ LE NYFGCQGC+CD+GG+
Sbjct: 629 QCHEAGTLSGIGECGQEDGDCSCKAHVTGDACDTCEDGFFSLEKSNYFGCQGCQCDIGGA 688
Query: 705 VSQVCDDLSGDCQCRNHMVGKNCNEPKKNYYLPDLHHMKYEIEDGTSPNGRGIRFGYDPQ 764
++ +C SG CQCR H+ GK C P+ NYY PDLHHMKYE+EDGT PNGR +RFG+DP
Sbjct: 689 LTTMCSGPSGVCQCREHVEGKQCQRPENNYYFPDLHHMKYEVEDGTGPNGRNLRFGFDPL 748
Query: 765 EFPSFSWRGYAQMSSIQNEVRITLNVNKQNLSLFRVILRYINPGTSVISGHITAHQTRPR 824
FP FSWRGYA M+S+QNEVR+ L+V + +LSLFR++LRYI+PGT ISG IT + ++
Sbjct: 749 VFPEFSWRGYAPMTSVQNEVRVRLSVRQSSLSLFRIVLRYISPGTEAISGRITLYSSQGD 808
Query: 825 NGTHQRKDIVFPPSREPSFVTVPGRNPADPFLLGPGTWILKIMAEGVLLDYLVLLPRDYF 884
+ Q + I FPPS+EP+FVTVPG A PF + PGTWI I EGVLLDYLVLLPRDY+
Sbjct: 809 SDALQSRKITFPPSKEPAFVTVPGNGFAGPFSITPGTWIACIQVEGVLLDYLVLLPRDYY 868
Query: 885 EAPILQLPVREPCTYSRHATTDNCLQYEHLPLERFSCVFGSEVTFFLQGGEYRKVVFQQP 944
EA LQ+PV EPC ++ + DNCL Y+HLPL FSC E FL GE R + +QP
Sbjct: 869 EAFTLQVPVTEPCAHTG-SPQDNCLLYQHLPLTAFSCTLACEARHFLLDGELRPLAMRQP 927
Query: 945 SAKHPLMSYISGQEVDLQIRLNVPQVGRYVIVLEYVNEHNKMYVGNVEIKSLGHMSEAKI 1004
+ HP M +SG+EV+LQ+RL VPQVG YV++LEY E +++V +V +KS G ++
Sbjct: 928 TPTHPAMVDLSGREVELQLRLRVPQVGHYVVLLEYATEVEQLFVVDVNLKSSGSALAGQV 987
Query: 1005 NLYNCKYSFLCRSVVTDDLNRIAVYDLLSDAEFRLRLPEIHFLLNKICIIPVEDFSLEYV 1064
N+Y+CKYS CRSVV D L+R AV++LL+DA+ +L+ HFLL ICIIP E+FS EY+
Sbjct: 988 NIYSCKYSIPCRSVVIDSLSRTAVHELLADADIQLKAHMAHFLLYHICIIPAEEFSTEYL 1047
Query: 1065 KPQLHCIATYGQXXXXXXXCIPSQYETPPLTVVLDALRNKGYQDSLRAPFPNAHTANGVT 1124
+PQ+HCIA+Y Q C+ +ETPP +LDA ++G +L P + A+GVT
Sbjct: 1048 RPQVHCIASYRQHANPSASCVSLAHETPPTASILDAT-SRGLFSAL--PHEPSSPADGVT 1104
Query: 1125 LTSSQNQITLRGRVIHLGRYVFIIHFYQPESPMFPVEVTIDGGQFWSGSSNASFCPHISG 1184
L + Q+Q+TL+G + HLGR+VF+IHFYQ E P FP EV ++GG+ WSGS ASFCPH+ G
Sbjct: 1105 LKAPQSQVTLKGLIPHLGRHVFVIHFYQAEHPGFPTEVIVNGGRQWSGSFLASFCPHLLG 1164
Query: 1185 CRGLVMAESQIELDIFKHDILVTVKIPNGKKMVLGHILAVPADSYSYTLLHQDTVDKSLN 1244
CR V+++ Q+E DI + ++ VTVKIP+GK + L +L VPA++Y Y +LH+ TVDKS
Sbjct: 1165 CRDQVISDGQVEFDISEAEVAVTVKIPDGKSLTLVRVLVVPAENYDYQILHKTTVDKSSE 1224
Query: 1245 FIYQCGENSFHITPVMSSEFCRNSVRSLVAAYNNGALPCNCHRNGAASPTCDPMGGQCPC 1304
FI CG +SF+I P +S FC+NS RSLVA Y+NGA+PC C G A C P GGQCPC
Sbjct: 1225 FISSCGGDSFYIDPQAASGFCKNSARSLVAFYHNGAIPCECDPAGTAGHHCSPEGGQCPC 1284
Query: 1305 KQNIIGLQCNRCRTGYYGFPFCKPCRCGWRLCDDITGKCICPPQTVKPRCEVCVRQHFGY 1364
+ N+IG QC+RC TGYYGFP+CKPC CG RLC+++TGKC+CPP TV+P+CEVC F +
Sbjct: 1285 RPNVIGRQCSRCATGYYGFPYCKPCNCGRRLCEEVTGKCLCPPHTVRPQCEVCEMNSFNF 1344
Query: 1365 HPLVGCVGCNCSSQGVVNAVNPECDKKNGQCRCRSGITGRRCDQCAPGSFGFPNCKPCNC 1424
HP+ GC CNCS +G + A ECD+ +GQCRC+ +TG++CD+CAPG + FP C PC+C
Sbjct: 1345 HPVAGCDVCNCSRKGTIEAAVSECDRDSGQCRCKPRVTGQQCDKCAPGFYQFPECVPCSC 1404
Query: 1425 NRGGTEPNVCDPQTGVCLCKENVEGIQCDMCRSGSFYLDSTNPKGCTNCFCFGATDICHS 1484
NR GTEP+VCDP+TG C+CKENVEG QC +CR GSFYLD TNPKGCT CFCFG C S
Sbjct: 1405 NRDGTEPSVCDPETGACMCKENVEGPQCQLCREGSFYLDPTNPKGCTKCFCFGVNTDCQS 1464
Query: 1485 TNKDRIKFVEMRNWRLKDVDNSMNIPVIFNPGSNSVVADVQELLPSVCNLYWVAPPSYLG 1544
++K R KFV+M WRL+ D +++PV FNPGSNS+VAD+QEL PSV + WVAPPSYLG
Sbjct: 1465 SHKQRAKFVDMMGWRLETADG-VDVPVSFNPGSNSMVADLQELPPSVHSASWVAPPSYLG 1523
Query: 1545 DKLSSYGGYLMYQVKTFGLPSEGMTLLQKRPDVQLTGQQMKLIYVDPNNPLPDKQYYGSV 1604
DK+SSYGGYL Y K+FGLP + M LL K+PDVQLTGQ M LI+ +P++P PD+ ++G V
Sbjct: 1524 DKVSSYGGYLTYHAKSFGLPGD-MVLLGKQPDVQLTGQHMSLIHKEPSDPRPDRLHHGRV 1582
Query: 1605 KLVEGNFRHASSNDLVTREELMMVLSRLEGLQIRGLYFTESQRLTLGEVGLEEATGTGSG 1664
+++EGNFRH S+ V+REELM VLSRLE L IRGL+FTE+QRLTLGEVGLEEA+ TGSG
Sbjct: 1583 QVIEGNFRHEGSSAPVSREELMTVLSRLERLHIRGLHFTETQRLTLGEVGLEEASDTGSG 1642
Query: 1665 NAAYNVETCSCPAGYLGDSCQECSPGFYRENRDRLTGRCIPCNCNGNSDRCLDGSGICLN 1724
A+ VE C+CP Y GDSCQ C PG+Y +N+ GRC+PCNCNG+S+RC DGSGIC+N
Sbjct: 1643 PRAHLVEMCACPPDYTGDSCQGCRPGYYWDNKSLPVGRCVPCNCNGHSNRCQDGSGICIN 1702
Query: 1725 CQHNTAGDNCEYCREGYFGDASQGNCRACRCPYTNSFASGCIENDGDIQCFCREGYTGVH 1784
CQHNTAG++CE C+ G++G+A G+CR C CP+TNSFA+GC + G ++C C+ GYTG
Sbjct: 1703 CQHNTAGEHCERCQAGHYGNAIHGSCRVCPCPHTNSFATGCAVDGGAVRCACKPGYTGTQ 1762
Query: 1785 CESCAPGYFGNPLKYGGFCQKCNCPNNGQLPNCDRLTGECINQEPKDIDPHEDCDACDSC 1844
CE CAPGYFGNP K+GG CQ CNC +NGQL CD LTG+C+NQEPKD P E+CD CDSC
Sbjct: 1763 CERCAPGYFGNPQKFGGSCQPCNCNSNGQLGPCDPLTGDCVNQEPKDGSPAEECDDCDSC 1822
Query: 1845 VITLLKDLSSMQDELQVIKFQMQNVNASTHTLGQMKHLEDRVKQLKSLLSRYRSVITTQG 1904
V+TLL DL+SM +EL+++K ++Q ++ ST L Q++H+E + K L++ L +RS ++ G
Sbjct: 1823 VMTLLNDLASMGEELRLVKSKLQGLSVSTGALEQIRHMETQAKDLRNQLLGFRSATSSHG 1882
Query: 1905 SKVDELDTDFIALNQNVNALREKAENNYKKAETLFNNFGKTNQRGKDLISKIQSLVININ 1964
SK+D+L+ + LN+ L+EKA+ N +KA+TL+NN +T Q K+L KI+++V N++
Sbjct: 1883 SKMDDLEKELSHLNREFETLQEKAQVNSRKAQTLYNNIDQTIQSAKELDMKIKNIVQNVH 1942
Query: 1965 VLLNQVPGTSGEGTSLPSGNAAEELAKARQMVNEMRDRNFGLQLREAEKENGKAQNLLDR 2024
+LL Q+ GEGT LP G+ + ELA+A++M+ ++R R+F L+EAE E +AQ LL R
Sbjct: 1943 ILLKQMARPGGEGTDLPVGDWSRELAEAQRMMRDLRSRDFKKHLQEAEAEKMEAQLLLHR 2002
Query: 2025 VKNELQKHQAENQGLIKIVRDSLNEYELKLNDLRESLKEAKEQTKLAETLNVDNKILFED 2084
++ L+ HQ EN GL+K +RDSLN+YE KL DLR L+EA Q K A +N +N+ +
Sbjct: 2003 IRTWLESHQVENNGLLKNIRDSLNDYEDKLQDLRSILQEAAAQAKQATGINHENEGVLGA 2062
Query: 2085 IKKRTEEMSKQQNEILDVLDSAEASLSKANSAFVLLQRSKEEYETLAAQLDGARKELTEK 2144
I+++ +EM +N+ L +A++SL + N+ + +S++EYE+LAA L+GAR+EL+++
Sbjct: 2063 IQRQMKEMDSLKNDFTKYLATADSSLLQTNNLLQQMDKSQKEYESLAAALNGARQELSDR 2122
Query: 2145 LKSHSLAASKEPLVVRAEEHAISLQELAKKLDEIKRNASNDELVACAMKAASAYEDXXXX 2204
++ S + K PLVV AE+HA SLQELAK+L+EIKRN S DELV CA+ AA+AYE+
Sbjct: 2123 VRELSRSGGKAPLVVEAEKHAQSLQELAKQLEEIKRNTSGDELVRCAVDAATAYENILNA 2182
Query: 2205 XXXXXXXXXXXXXXXXXXVSTMEKKDLAGRANRLKTSSGNLLNQAQAAQKTLQEISPTLD 2264
T+ K+DL RA L + S LLN+A+ QK LQ++SP L+
Sbjct: 2183 IRAAEDAASKATSASKSAFQTVIKEDLPKRAKTLSSDSEELLNEAKMTQKRLQQVSPALN 2242
Query: 2265 NVKSRLQDAERKKNMIQGDLTDFQNQLQGMKRDDIESMIMNAKNMVKNANDITTNVLDEL 2324
+++ L+ +K+++ +LT ++ L G++R DI+S+++ AK+MV+ AN IT+ VLD L
Sbjct: 2243 SLQQTLKTVSVQKDLLDANLTVARDDLHGIQRGDIDSVVIGAKSMVREANGITSEVLDGL 2302
Query: 2325 DPIKTDVENIKNTYGTMQSADFDNALKKANNTVNNLTNILPDLFNKITSINQQLMPXXXX 2384
+PI+TD+ IK++Y + + DF AL ANN+V LT LPDLF KI SINQQL+P
Sbjct: 2303 NPIQTDLGRIKDSYESARREDFSKALVDANNSVKKLTRKLPDLFIKIESINQQLLPLGNI 2362
Query: 2385 XXXXXXXXXLIQQARDAANKVAIPMRFDGSSGVEVRPPDILEDLKGYTSLSLFLQRPLSR 2444
LIQQARDAANKVAIPMRF+G SGVEVR P+ LEDLKGYTSLSLFLQRP R
Sbjct: 2363 SDNVDRIRELIQQARDAANKVAIPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPDLR 2422
Query: 2445 LDSPQQTSDMFVMYLGDKDSSKDYIGMAVRGGRLICAYSLGGNEAEIEVLETVSDSDTRE 2504
+ T DMFVMYLG+KD+SKDYIGMAV G+L C Y+LG EAE+++ + +++S+++E
Sbjct: 2423 ENGG--TEDMFVMYLGNKDASKDYIGMAVVDGQLTCVYNLGDREAEVQIDQVLTESESQE 2480
Query: 2505 ATMDLVKFERIYQYAKLNYIKGATSSSPLSLGPYEDSSGDQYTLLDLNPDNVVFYVGGYP 2564
A MD VKF+RIYQ+AKLNY K ATS+ P + G Y+ S TLL+L+P+N VFYVGGYP
Sbjct: 2481 AVMDRVKFQRIYQFAKLNYTKEATSTKPKAPGVYDMESASSNTLLNLDPENAVFYVGGYP 2540
Query: 2565 PDFTPPDTLNHPRYEGCIEFDSLNERVLSLYNFKRTFNLNTTLVQPCRRYKEQSAKIYFE 2624
P F P L P Y+GCIE D LNE VLSLYNFK TFNLNTT V+PCRR KE+S K YFE
Sbjct: 2541 PGFELPRRLRFPPYKGCIELDDLNENVLSLYNFKTTFNLNTTEVEPCRRRKEESDKNYFE 2600
Query: 2625 GTGYARVNAAPPSVSHIRYEQTIQTTADEGLVFFAENQDKFISLRIEEGHLIFRYKIDSQ 2684
GTGYAR+ P+ + QTIQTT D GL+FFAENQD FISL IE+G+L+ +YK++S+
Sbjct: 2601 GTGYARI-PTQPNAPFPNFMQTIQTTVDRGLLFFAENQDNFISLNIEDGNLMVKYKLNSE 2659
Query: 2685 PPKEKESSLIINNGMDQVVSVSPTTITQKQFTLIDKSTVQAKATTFRFDSYYLGGAPNSL 2744
PPKEK INNG D ++ +S ++ ++K ++ + F F +YYLGG P ++
Sbjct: 2660 PPKEKGIRDTINNGRDHMILISIGKSQKRMLINMNKHSIIIEGEIFDFSTYYLGGIPIAI 2719
Query: 2745 RERFNITTPPFRGCMMNVRXXXXXXXXXXXXLGVSRKCPDDWKIVRVASFSKNGVLGLSD 2804
RERFNI+TP F+GCM N++ +GV++KC +DWK+VR ASFS+ G + ++
Sbjct: 2720 RERFNISTPAFQGCMKNLKKTSGVVRLNDT-VGVTKKCSEDWKLVRTASFSRGGQMSFTN 2778
Query: 2805 EGFQFPNDFQVGFGFHTLALDGTLLNYNLRSDIFSVILRNGSVIVRIADEE--IQSSKG- 2861
+ FQ+ FGF T GTLLN+ R+ V L +G + + D I S G
Sbjct: 2779 LDVPSLDRFQLSFGFQTFQPSGTLLNHQTRTSSLLVTLEDGHIALSTRDSSSPIFKSPGT 2838
Query: 2862 YGDGVIHYVTVMKEDDTLRVIIDDASELTMFPPAGRKMLSHPIDLGGNNFEGCIFNVFIQ 2921
Y DG++H+V+V+ + LR++IDD A + +GG FEGCI NVF+Q
Sbjct: 2839 YMDGLLHHVSVISDTSGLRLLIDDQVLRRNQRLASFSNAQQSLSMGGGYFEGCISNVFVQ 2898
Query: 2922 RKGQFPHVQSLTNYDRKTDVSLGFCMIRRQPQPMLLRELAGKDKHAVKRSWMI--LVPDK 2979
R Q P V + + K D LG C + + P ML + G +K RS+ + L+ D
Sbjct: 2899 RMSQSPEVLDMASKSTKRDAFLGGCSLNKPPFLMLFKSPKGFNK---ARSFNVNQLLQDA 2955
Query: 2980 LKIGTKFP--KDTTSHL--IRVSSITGAYHFGNTPDTYLLFTSSQMSSRGRHLRSHFAVD 3035
+ +D S L + + A FG++P ++LLF Q + R F++D
Sbjct: 2956 PQAARSIEAWQDGKSCLPPLNTKATHRALQFGDSPTSHLLFKLPQELLKPR---LQFSLD 3012
Query: 3036 VRTTSSRGLIFFMGEKLENRYITLYLSKGRFVFLLAADGRKIKIKSKAKYSDGQWHTVAF 3095
++TTSSRGL+F G + + ++ LYLS+G +F L A G+K++++SK +Y DG+WH+V F
Sbjct: 3013 IQTTSSRGLVFHTGTR--DSFVALYLSEGHVIFALGAGGKKLRLRSKERYHDGKWHSVVF 3070
Query: 3096 SQTGEKMRLIVDGLNARQGNIPPTFSIRTESPIYLGGVPSLKIQNIPKKSFVGCLRAFNV 3155
+G K+ L+VDGL A++G++P +I +YLG PS K +++P+ SFVGCLR F +
Sbjct: 3071 GLSGRKVHLVVDGLRAQEGSLPGNSTISPREQVYLGLSPSRKSKSLPQHSFVGCLRNFQL 3130
Query: 3156 GGKPVHTYHQNSGVLPCLDNTLEKGIAFFNEGGHVVIERTFLMNLDYKIAFSIRPRSSTS 3215
KP+ + SGV PCL +LEKGI F GGHVV+ + + + SIRPRS T
Sbjct: 3131 DSKPLDSPSARSGVSPCLGGSLEKGIYFSQGGGHVVLANSVSLEPALTLTLSIRPRSLTG 3190
Query: 3216 LLIHIGTKQENYFAVYMDKGVVTASGNNGAGEFLTSLTPQQSLCDGKWHSIAVTQKKNTV 3275
+LIHI ++ + +VYM+ G VT S N+ AG +TS+TP++SLCDG+WHS+ V+ K++T+
Sbjct: 3191 VLIHIASQSGEHLSVYMEAGKVTTSMNSEAGGTVTSITPKRSLCDGQWHSVTVSIKQHTL 3250
Query: 3276 HLDVDTMSNYTTGPSTVLSTSHAQPLYFGRVPANLEMPWLPVQDMFLGCLKDVKINDKPV 3335
HL++DT ++YT G + S L+ G VP L+M LPV + F GCLK++++N PV
Sbjct: 3251 HLELDTDNSYTAGQLSFPPNSTRGSLHIGGVPDKLKMLTLPVWNSFFGCLKNIQVNHIPV 3310
Query: 3336 LIRKNADIHGGVSLQGCP 3353
I + D+ G VSL GCP
Sbjct: 3311 PITEATDVQGSVSLNGCP 3328
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